Small molecule tools for structural and functional studies of 2OG oxygenases by Lesniak, R

Human carnitine biosynthesis proceeds via (2S,3S)-3-hydroxy-N(ε)-trimethyllysine by Leśniak, R, Markolovic, S, Tars, K, Schofield, C

Development and application of ligand-based NMR screening assays for γ-butyrobetaine hydroxylase by Claridge, T, Schofield, C, Brem, J, Rydzik, A, Khan, A, Lesniak, R, Choi, H, Leung, I, McDonough, M

Small-molecules that covalently react with a human prolyl hydroxylase – towards activity modulation and substrate capture by Bush, J, Lesniak, R, Yeh, T, Belle, R, Kramer, H, Tumber, A, Chowdhury, R, Flashman, E, Mecinovic, J, Schofield, C

Crystallographic analyses of isoquinoline complexes reveal a new mode of metallo-β-lactamase inhibition by Li, G, Brem, J, Lesniak, R, Abboud, M, Lohans, C, Clifton, I, Yang, S, Jiménez-Castellanos, J, Avison, M, Spencer, J, McDonough, M, Schofield, C

High-throughput crystallography reveals boron-containing inhibitors of a penicillin-binding protein with di- and tricovalent binding modes by Newman, H, Krajnc, A, Bellini, D, Eyermann, CJ, Boyle, GA, Paterson, NG, McAuley, KE, Lesniak, R, Gangar, M, Brem, J, Schofield, CJ, von Delft, F, Chibale, K, Dowson, CG

Discovery and characterization of GSK2801, a selective chemical probe for the bromodomains BAZ2A and BAZ2B by Chen, P, Chaikuad, A, Bamborough, P, Bantscheff, M, Bountra, C, Chung, C, Fedorov, O, Grandi, P, Jung, D, Lesniak, R, Lindon, M, Müller, S, Philpott, M, Prinjha, R, Rogers, C, Selenski, C, Tallant, C, Werner, T, Willson, T, Knapp, S, Drewry, D

The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases by Markolovic, S, Zhuang, Q, Wilkins, SE, Eaton, CD, Abboud, MI, Katz, MJ, McNeil, HE, Leśniak, R, Hall, C, Struwe, WB, Konietzny, R, Davis, S, Yang, M, Ge, W, Benesch, JLP, Kessler, BM, Ratcliffe, PJ, Cockman, ME, Fischer, R, Wappner, P, Chowdhury, R, Coleman, M, Schofield, CJ