Runx1 shapes the chromatin landscape via a cascade of direct and indirect targets. by Matthew R Hass, Daniel Brissette, Sreeja Parameswaran, Mario Pujato, Omer Donmez, Leah C Kottyan, Matthew T Weirauch, Raphael Kopan

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502 The epigenetics of the now known 330 lupus genetic risk loci in two ancestries are independently consonant with causal regulatory mechanisms involving epstein-barr virus (EBV)-... by John B Harley, Viktoryia Laurynenka, Sreeja Parameswaran, Xiaoting Chen, Leah C Kottyan, Matthew T Weirauch, Kenneth M Kaufman, Iouri Chepelev

4277 Functional consequences of the juvenile idiopathic arthritis risk variant at 1q24.3 by Halima Moncrieffe, Katelyn Dunn, Yongbo Huang, Xiaoting Chen, Carl D. Langefeld, Matthew T. Weirauch, John B. Harley, Leah C. Kottyan, Susan D. Thompson

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CASCADE: high-throughput characterization of regulatory complex binding altered by non-coding variants by David Bray, Heather Hook, Rose Zhao, Jessica L. Keenan, Ashley Penvose, Yemi Osayame, Nima Mohaghegh, Xiaoting Chen, Sreeja Parameswaran, Leah C. Kottyan, Matthew T. Weirauch, Trevor Siggers

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Genome-wide epigenetic profiling and transcriptome analysis in pediatric Obstructive Sleep Apnea: A focus on Black female children by Bala S.C. Koritala, Sreeja Parameswaran, Omer A. Donmez, Carmy Forney, Hope Rowden, Charles A. Moore, Angela L. Duggins, Alexandra Sestito, Brittany A. Leader, Matthew T. Weirauch, Leah C. Kottyan, David F. Smith

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A functional mechanism for a non-coding variant near AGTR2 associated with risk for preterm birth by Li Wang, Robert M. Rossi, Xiaoting Chen, Jing Chen, Jilian Runyon, Mehak Chawla, Daniel Miller, Carmy Forney, Arthur Lynch, Xuzhe Zhang, Fansheng Kong, Bo Jacobsson, Leah C. Kottyan, Matthew T. Weirauch, Ge Zhang, Louis J. Muglia

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maxATAC: Genome-scale transcription-factor binding prediction from ATAC-seq with deep neural networks. by Tareian A Cazares, Faiz W Rizvi, Balaji Iyer, Xiaoting Chen, Michael Kotliar, Anthony T Bejjani, Joseph A Wayman, Omer Donmez, Benjamin Wronowski, Sreeja Parameswaran, Leah C Kottyan, Artem Barski, Matthew T Weirauch, V B Surya Prasath, Emily R Miraldi

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Epigenetic and transcriptional dysregulation in CD4+ T cells in patients with atopic dermatitis. by Amy A Eapen, Sreeja Parameswaran, Carmy Forney, Lee E Edsall, Daniel Miller, Omer Donmez, Katelyn Dunn, Xiaoming Lu, Marissa Granitto, Hope Rowden, Adam Z Magier, Mario Pujato, Xiaoting Chen, Kenneth Kaufman, David I Bernstein, Ashley L Devonshire, Marc E Rothenberg, Matthew T Weirauch, Leah C Kottyan

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Risk factors affecting polygenic score performance across diverse cohorts by Daniel Hui, Scott Dudek, Krzysztof Kiryluk, Theresa L Walunas, Iftikhar J Kullo, Wei-Qi Wei, Hemant Tiwari, Josh F Peterson, Wendy K Chung, Brittney H Davis, Atlas Khan, Leah C Kottyan, Nita A Limdi, Qiping Feng, Megan J Puckelwartz, Chunhua Weng, Johanna L Smith, Elizabeth W Karlson, Regeneron Genetics Center, Penn Medicine BioBank, Gail P Jarvik, Marylyn D Ritchie

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Genome-wide meta-analysis identifies novel risk loci for uterine fibroids within and across multiple ancestry groups by Jeewoo Kim, Ariel Williams, Hannah Noh, Elizabeth A. Jasper, Sarah H. Jones, James A. Jaworski, Megan M. Shuey, Edward A. Ruiz-Narváez, Lauren A. Wise, Julie R. Palmer, John Connolly, Jacob M. Keaton, Joshua C. Denny, Atlas Khan, Mohammad A. Abbass, Laura J. Rasmussen-Torvik, Leah C. Kottyan, Purnima Madhivanan, Karl Krupp, Wei-Qi Wei, Todd L. Edwards, Digna R. Velez Edwards, Jacklyn N. Hellwege

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Shared and distinct interactions of type 1 and type 2 Epstein-Barr Nuclear Antigen 2 with the human genome by Kenyatta C. M. F. Viel, Sreeja Parameswaran, Omer A. Donmez, Carmy R. Forney, Matthew R. Hass, Cailing Yin, Sydney H. Jones, Hayley K. Prosser, Arame A. Diouf, Olivia E. Gittens, Lee E. Edsall, Xiaoting Chen, Hope Rowden, Katelyn A. Dunn, Rui Guo, Andrew VonHandorf, Merrin Man Long Leong, Kevin Ernst, Kenneth M. Kaufman, Lucinda P. Lawson, Ben Gewurz, Bo Zhao, Leah C. Kottyan, Matthew T. Weirauch

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Genome-wide association and multi-trait analyses characterize the common genetic architecture of heart failure by Michael G. Levin, Noah L. Tsao, Pankhuri Singhal, Chang Liu, Ha My T. Vy, Ishan Paranjpe, Joshua D. Backman, Tiffany R. Bellomo, William P. Bone, Kiran J. Biddinger, Qin Hui, Ozan Dikilitas, Benjamin A. Satterfield, Yifan Yang, Michael P. Morley, Yuki Bradford, Megan Burke, Nosheen Reza, Brian Charest, Regeneron Genetics Center, Renae L. Judy, Megan J. Puckelwartz, Hakon Hakonarson, Atlas Khan, Leah C. Kottyan, Iftikhar Kullo, Yuan Luo, Elizabeth M. McNally, Laura J. Rasmussen-Torvik, Sharlene M. Day, Ron Do, Lawrence S. Phillips, Patrick T. Ellinor, Girish N. Nadkarni, Marylyn D. Ritchie, Zoltan Arany, Thomas P. Cappola, Kenneth B. Margulies, Krishna G. Aragam, Christopher M. Haggerty, Jacob Joseph, Yan V. Sun, Benjamin F. Voight, Scott M. Damrauer

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Author Correction: Genetic regulation of serum IgA levels and susceptibility to common immune, infectious, kidney, and cardio-metabolic traits by Lili Liu, Atlas Khan, Elena Sanchez-Rodriguez, Francesca Zanoni, Yifu Li, Nicholas Steers, Olivia Balderes, Junying Zhang, Priya Krithivasan, Robert A. LeDesma, Clara Fischman, Scott J. Hebbring, John B. Harley, Halima Moncrieffe, Leah C. Kottyan, Bahram Namjou-Khales, Theresa L. Walunas, Rachel Knevel, Soumya Raychaudhuri, Elizabeth W. Karlson, Joshua C. Denny, Ian B. Stanaway, David Crosslin, Thomas Rauen, Jürgen Floege, Frank Eitner, Zina Moldoveanu, Colin Reily, Barbora Knoppova, Stacy Hall, Justin T. Sheff, Bruce A. Julian, Robert J. Wyatt, Hitoshi Suzuki, Jingyuan Xie, Nan Chen, Xujie Zhou, Hong Zhang, Lennart Hammarström, Alexander Viktorin, Patrik K. E. Magnusson, Ning Shang, George Hripcsak, Chunhua Weng, Tatjana Rundek, Mitchell S. V. Elkind, Elizabeth C. Oelsner, R. Graham Barr, Iuliana Ionita-Laza, Jan Novak, Ali G. Gharavi, Krzysztof Kiryluk

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Genetic regulation of serum IgA levels and susceptibility to common immune, infectious, kidney, and cardio-metabolic traits by Lili Liu, Atlas Khan, Elena Sanchez-Rodriguez, Francesca Zanoni, Yifu Li, Nicholas Steers, Olivia Balderes, Junying Zhang, Priya Krithivasan, Robert A. LeDesma, Clara Fischman, Scott J. Hebbring, John B. Harley, Halima Moncrieffe, Leah C. Kottyan, Bahram Namjou-Khales, Theresa L. Walunas, Rachel Knevel, Soumya Raychaudhuri, Elizabeth W. Karlson, Joshua C. Denny, Ian B. Stanaway, David Crosslin, Thomas Rauen, Jürgen Floege, Frank Eitner, Zina Moldoveanu, Colin Reily, Barbora Knoppova, Stacy Hall, Justin T. Sheff, Bruce A. Julian, Robert J. Wyatt, Hitoshi Suzuki, Jingyuan Xie, Nan Chen, Xujie Zhou, Hong Zhang, Lennart Hammarström, Alexander Viktorin, Patrik K. E. Magnusson, Ning Shang, George Hripcsak, Chunhua Weng, Tatjana Rundek, Mitchell S. V. Elkind, Elizabeth C. Oelsner, R. Graham Barr, Iuliana Ionita-Laza, Jan Novak, Ali G. Gharavi, Krzysztof Kiryluk

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Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets by Kelsey M. Haas, Michael J. McGregor, Mehdi Bouhaddou, Benjamin J. Polacco, Eun-Young Kim, Thong T. Nguyen, Billy W. Newton, Matthew Urbanowski, Heejin Kim, Michael A. P. Williams, Veronica V. Rezelj, Alexandra Hardy, Andrea Fossati, Erica J. Stevenson, Ellie Sukerman, Tiffany Kim, Sudhir Penugonda, Elena Moreno, Hannes Braberg, Yuan Zhou, Giorgi Metreveli, Bhavya Harjai, Tia A. Tummino, James E. Melnyk, Margaret Soucheray, Jyoti Batra, Lars Pache, Laura Martin-Sancho, Jared Carlson-Stevermer, Alexander S. Jureka, Christopher F. Basler, Kevan M. Shokat, Brian K. Shoichet, Leah P. Shriver, Jeffrey R. Johnson, Megan L. Shaw, Sumit K. Chanda, Dan M. Roden, Tonia C. Carter, Leah C. Kottyan, Rex L. Chisholm, Jennifer A. Pacheco, Maureen E. Smith, Steven J. Schrodi, Randy A. Albrecht, Marco Vignuzzi, Lorena Zuliani-Alvarez, Danielle L. Swaney, Manon Eckhardt, Steven M. Wolinsky, Kris M. White, Judd F. Hultquist, Robyn M. Kaake, Adolfo García-Sastre, Nevan J. Krogan

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