A comparison of Bayesian and frequentist approaches to incorporating clinical and biological information for the prediction of response to standardized pediatric colitis therapy by Zhu Wang, Jia Nie, Xing Song, Lee A. Denson, Jeffrey S. Hyams

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Self-Management assistance for recommended treatment (SMART) IBD app randomized control trial in adolescents with IBD: Design and methodology by Caroline M. Roberts, Jill M. Plevinsky, Kaitlyn L. Gamwell, Amy E. Noser, Lee A. Denson, Kevin A. Hommel

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Reduced LHFPL3-AS2 lncRNA expression is linked to altered epithelial polarity and proliferation, and to ileal ulceration in Crohn disease by Katya E. Sosnovski, Tzipi Braun, Amnon Amir, Marina BenShoshan, Haya Abbas-Egbariya, Rakefet Ben-Yishay, Liat Anafi, Camilla Avivi, Iris Barshack, Lee A. Denson, Yael Haberman

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Interleukin-22 levels are increased in gastrointestinal graft-versus-host disease in children by Dana T. Lounder, Pooja Khandelwal, Nicholas J. Gloude, Christopher E. Dandoy, Sonata Jodele, Mario Medvedovic, Lee A. Denson, Adam Lane, Kelly Lake, Bridget Litts, Alyss Wilkey, Stella M. Davies

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Ileal Crohn’s Disease Exhibits Reduced Activity of Phospholipase C-β3-Dependent Wnt/β-Catenin Signaling Pathway by Tomoaki Ando, Ikuo Takazawa, Zachary T. Spencer, Ryoji Ito, Yoshiaki Tomimori, Zbigniew Mikulski, Kenji Matsumoto, Tohru Ishitani, Lee A. Denson, Yu Kawakami, Yuko Kawakami, Jiro Kitaura, Yashi Ahmed, Toshiaki Kawakami

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Longitudinal DNA methylation profiling of the rectal mucosa identifies cell-specific signatures of disease status, severity and clinical outcomes in ulcerative colitis cell-specifi... by Suresh Venkateswaran, Hari K. Somineni, Jason D. Matthews, Varun Kilaru, Jeffrey S. Hyams, Lee A. Denson, Richard Kellamayer, Greg Gibson, David J. Cutler, Karen N. Conneely, Alicia K. Smith, Subra Kugathasan

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Methylation quantitative trait loci are largely consistent across disease states in Crohn’s disease by Suresh Venkateswaran, Hari K Somineni, Varun Kilaru, Seyma Katrinli, Jarod Prince, David T Okou, Jeffrey S Hyams, Lee A Denson, Richard Kellermayer, Greg Gibson, David J Cutler, Alicia K Smith, Subra Kugathasan, Karen N Conneely

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Transcriptome analysis in acute gastrointestinal graft-<i>versus</i> host disease reveals a unique signature in children and shared biology with pediatric inflammatory bowel diseas... by Pooja Khandelwal, Dana T Lounder, Allison Bartlett, Yael Haberman, Anil G. Jegga, Sudhir Ghandikota, Jane Koo, Nathan Luebbering, Daniel Leino, Sheyar Abdullah, Michaela Loveless, Phillip Minar, Kelly Lake, Bridget Litts, Rebekah Karns, Adam S. Nelson, Lee A. Denson, Stella M. Davies

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Serum Matrix Metalloproteinase 7 Is a Diagnostic Biomarker of Biliary Injury and Fibrosis in Pediatric Autoimmune Liver Disease by Simon Lam, Ruchi Singh, Jonathan R. Dillman, Andrew T. Trout, Suraj D. Serai, Divya Sharma, Rachel Sheridan, Weizhe Su, Lin Fei, Rebekah Karns, Marija M. Haramija, Ged Ridgway, Marc Goldfinger, James E. Squires, Lee A. Denson, Jeffery S. Hyams, Alexander G. Miethke

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Deriving Human Intestinal Organoids with Functional Tissue-Resident Macrophages All From Pluripotent Stem CellsSummary by Kentaro Tominaga, Daniel O. Kechele, J. Guillermo Sanchez, Simon Vales, Ingrid Jurickova, Lizza Roman, Akihiro Asai, Jacob R. Enriquez, Heather A. McCauley, Keishi Kishimoto, Kentaro Iwasawa, Akaljot Singh, Yuko Horio, Jorge O. Múnera, Takanori Takebe, Aaron M. Zorn, Michael A. Helmrath, Lee A. Denson, James M. Wells

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Machine-learning-based integrative –‘omics analyses reveal immunologic and metabolic dysregulation in environmental enteric dysfunction by Fatima Zulqarnain, Xueheng Zhao, Kenneth D.R. Setchell, Yash Sharma, Phillip Fernandes, Sanjana Srivastava, Aman Shrivastava, Lubaina Ehsan, Varun Jain, Shyam Raghavan, Christopher Moskaluk, Yael Haberman, Lee A. Denson, Khyati Mehta, Najeeha T. Iqbal, Najeeb Rahman, Kamran Sadiq, Zubair Ahmad, Romana Idress, Junaid Iqbal, Sheraz Ahmed, Aneeta Hotwani, Fayyaz Umrani, Beatrice Amadi, Paul Kelly, Donald E. Brown, Sean R. Moore, Syed Asad Ali, Sana Syed

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Mucosal transcriptomics highlight lncRNAs implicated in ulcerative colitis, Crohn’s disease, and celiac disease by Tzipi Braun, Katya E. Sosnovski, Amnon Amir, Marina BenShoshan, Kelli L. VanDussen, Rebekah Karns, Nina Levhar, Haya Abbas-Egbariya, Rotem Hadar, Gilat Efroni, David Castel, Camila Avivi, Michael J. Rosen, Anne M. Grifiths, Thomas D. Walters, David R. Mack, Brendan M. Boyle, Syed Asad Ali, Sean R. Moore, Melanie Schirmer, Ramnik J. Xavier, Subra Kugathasan, Anil G. Jegga, Batya Weiss, Chen Mayer, Iris Barshack, Shomron Ben-Horin, Igor Ulitsky, Anthony Beucher, Jorge Ferrer, Jeffrey S. Hyams, Lee A. Denson, Yael Haberman

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Identifying high-impact variants and genes in exomes of Ashkenazi Jewish inflammatory bowel disease patients by Yiming Wu, Kyle Gettler, Meltem Ece Kars, Mamta Giri, Dalin Li, Cigdem Sevim Bayrak, Peng Zhang, Aayushee Jain, Patrick Maffucci, Ksenija Sabic, Tielman Van Vleck, Girish Nadkarni, Lee A. Denson, Harry Ostrer, Adam P. Levine, Elena R. Schiff, Anthony W. Segal, Subra Kugathasan, Peter D. Stenson, David N. Cooper, L. Philip Schumm, Scott Snapper, Mark J. Daly, Talin Haritunians, Richard H. Duerr, Mark S. Silverberg, John D. Rioux, Steven R. Brant, Dermot P. B. McGovern, Judy H. Cho, Yuval Itan

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