Targeting of GFP-Cre to the mouse Cyp11a1 locus both drives cre recombinase expression in steroidogenic cells and permits generation of Cyp11a1 knock out mice. by Laura O'Hara, Jean Philippe York, Pumin Zhang, Lee B Smith

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New Insights into Testosterone Biosynthesis: Novel Observations from HSD17B3 Deficient Mice by Ben M. Lawrence, Liza O’Donnell, Lee B. Smith, Diane Rebourcet

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Specific Transcriptomic Signatures and Dual Regulation of Steroidogenesis Between Fetal and Adult Mouse Leydig Cells by Pauline Sararols, Isabelle Stévant, Yasmine Neirijnck, Diane Rebourcet, Annalucia Darbey, Michael K. Curley, Françoise Kühne, Emmanouil Dermitzakis, Emmanouil Dermitzakis, Lee B. Smith, Lee B. Smith, Serge Nef

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Modelling steroidogenesis: a framework model to support hypothesis generation and testing across endocrine studies by Laura O’Hara, Peter J. O’Shaughnessy, Tom C. Freeman, Lee B. Smith

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Pituitary androgen receptor signalling regulates prolactin but not gonadotrophins in the male mouse. by Laura O'Hara, Michael Curley, Maria Tedim Ferreira, Lyndsey Cruickshanks, Laura Milne, Lee B Smith

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Influence of Androgen Receptor in Vascular Cells on Reperfusion following Hindlimb Ischaemia. by Junxi Wu, Patrick W F Hadoke, Kaloyan Takov, Agnieszka Korczak, Martin A Denvir, Lee B Smith

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LKB1 is an essential regulator of spermatozoa release during spermiation in the mammalian testis. by Fiona C Denison, Lee B Smith, Phillip J Muckett, Laura O'Hara, David Carling, Angela Woods

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Androgen Receptor Is Dispensable for X-Zone Regression in the Female Adrenal but Regulates Post-Partum Corticosterone Levels and Protects Cortex Integrity by Anne-Louise Gannon, Anne-Louise Gannon, Laura O’Hara, Laura O’Hara, Ian J. Mason, Anne Jørgensen, Anne Jørgensen, Hanne Frederiksen, Hanne Frederiksen, Michael Curley, Laura Milne, Sarah Smith, Rod T. Mitchell, Lee B. Smith, Lee B. Smith

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Androgen action via testicular arteriole smooth muscle cells is important for Leydig cell function, vasomotion and testicular fluid dynamics. by Michelle Welsh, Richard M Sharpe, Lindsey Moffat, Nina Atanassova, Philippa T K Saunders, Sigrid Kilter, Anders Bergh, Lee B Smith

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Germ cell-specific targeting of DICER or DGCR8 reveals a novel role for endo-siRNAs in the progression of mammalian spermatogenesis and male fertility. by Céline Zimmermann, Yannick Romero, Maria Warnefors, Adem Bilican, Christelle Borel, Lee B Smith, Noora Kotaja, Henrik Kaessmann, Serge Nef

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Relationship of transcriptional markers to Leydig cell number in the mouse testis. by Diane Rebourcet, Ana Monteiro, Lyndsey Cruickshanks, Nathan Jeffery, Sarah Smith, Laura Milne, Peter J O'Shaughnessy, Lee B Smith

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Acute versus chronic loss of mammalian Azi1/Cep131 results in distinct ciliary phenotypes. by Emma A Hall, Margaret Keighren, Matthew J Ford, Tracey Davey, Andrew P Jarman, Lee B Smith, Ian J Jackson, Pleasantine Mill

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Fertility Preservation in Childhood Cancer: Endocrine Activity in Prepubertal Human Testis Xenografts Exposed to a Pubertal Hormone Environment by Marsida Hutka, Prashant Kadam, Dorien Van Saen, Natalie Z. M. Homer, Jaime Onofre, W. Hamish B. Wallace, Lee B. Smith, Jan-Bernd Stukenborg, Ellen Goossens, Rod T. Mitchell

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A Novel Model Using AAV9-Cre to Knockout Adult Leydig Cell Gene Expression Reveals a Physiological Role of Glucocorticoid Receptor Signalling in Leydig Cell Function by Anne-Louise Gannon, Annalucia L. Darbey, Grace Chensee, Ben M. Lawrence, Liza O’Donnell, Joanna Kelso, Natalie Reed, Shanmathi Parameswaran, Sarah Smith, Lee B. Smith, Diane Rebourcet

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Low-dose tamoxifen treatment in juvenile males has long-term adverse effects on the reproductive system: implications for inducible transgenics by Saloni H. Patel, Laura O’Hara, Nina Atanassova, Sarah E. Smith, Michael K. Curley, Diane Rebourcet, Annalucia L. Darbey, Anne-Louise Gannon, Richard M. Sharpe, Lee B. Smith

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A role for steroid 5 alpha-reductase 1 in vascular remodeling during endometrial decidualization by Isaac W. Shaw, Phoebe M. Kirkwood, Diane Rebourcet, Fiona L. Cousins, Rebecca J. Ainslie, Dawn E. W. Livingstone, Lee B. Smith, Philippa T.K. Saunders, Douglas A. Gibson

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Diethylstilboestrol exposure does not reduce testosterone production in human fetal testis xenografts. by Rod T Mitchell, Richard M Sharpe, Richard A Anderson, Chris McKinnell, Sheila Macpherson, Lee B Smith, W Hamish B Wallace, Christopher J H Kelnar, Sander van den Driesche

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Sertoli cell-enriched proteins in mouse and human testicular interstitial fluid by Liza O’Donnell, Laura F. Dagley, Michael Curley, Annalucia Darbey, Peter J. O’Shaughnessy, Thorsten Diemer, Adrian Pilatz, Daniela Fietz, Peter G. Stanton, Lee B. Smith, Diane Rebourcet

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Modelling the Structure and Dynamics of Biological Pathways. by Laura O'Hara, Alessandra Livigni, Thanos Theo, Benjamin Boyer, Tim Angus, Derek Wright, Sz-Hau Chen, Sobia Raza, Mark W Barnett, Paul Digard, Lee B Smith, Tom C Freeman

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Proposed role for COUP-TFII in regulating fetal Leydig cell steroidogenesis, perturbation of which leads to masculinization disorders in rodents. by Sander van den Driesche, Marion Walker, Chris McKinnell, Hayley M Scott, Sharon L Eddie, Rod T Mitchell, Jonathan R Seckl, Amanda J Drake, Lee B Smith, Richard A Anderson, Richard M Sharpe

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