A mixed methods case study investigating how randomised controlled trials (RCTs) are reported, understood and interpreted in practice by Ben E. Byrne, Leila Rooshenas, Helen S. Lambert, Jane M. Blazeby

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74:poster Understanding patients’ views and experiences of NHS services in the context of the Evidence-Based Interventions (EBI) programme in the English National Health Service... by Amanda Owen-Smith, Leila Rooshenas, William Hollingworth, Nicola Farrar, Carmel Conefrey, Josie Morley

Pre-trial qualitative work with health care professionals to refine the design and delivery of a randomised controlled trial on kidney care by Samantha Husbands, Fergus Caskey, Helen Winton, Andy Gibson, Jenny L. Donovan, Leila Rooshenas

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Recruiters’ perspectives and experiences of trial recruitment processes: a qualitative evidence synthesis protocol by Leila Rooshenas, Bridget Young, Jenny Donovan, Marcus Jepson, Daisy Elliott, Nicola Farrar, Catherine Houghton

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129:oral What are commissioners’ experiences of implementing a national programme seeking to reduce non-evidence-based healthcare in the NHS during the COVID-19 pandemic? by Leila Rooshenas, William Hollingworth, Tim Jones, Joel Glynn, Nicola Farrar, Carmel Conefrey, Josie Morley

‘It’s basically ‘have that or die’’: a qualitative study of older patients’ choices between dialysis and conservative kidney management by Joanna Coast, Fergus Caskey, Leila Rooshenas, Barnaby Hole, Lucy Selman, Miranda Scanlon, Rachael Morton

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Longitudinal study of use and cost of subacromial decompression surgery: the need for effective evaluation of surgical procedures to prevent overtreatment and wasted resources by Leila Rooshenas, Jenny Donovan, William Hollingworth, David Beard, Tim Jones, Andrew J Carr, Myles-Jay Linton

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Non-COVID-19 UK clinical trials and the COVID-19 pandemic: impact, challenges and possible solutions by Ava Lorenc, Leila Rooshenas, Carmel Conefrey, Julia Wade, Nicola Farrar, Nicola Mills, Sangeetha Paramasivan, Alba Realpe, Marcus Jepson

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Reducing the carbon footprint of research: experience from the NightLife study by Leila Rooshenas, Niamh Quann, Carla Richardson, James O Burton, Helen Eborall, Carmel Conefrey, Katherine L Hull, Steph Burns, Victoria Cluley, Kateryna MacConaill

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Understanding the perspectives of recruiters is key to improving randomised controlled trial enrolment: a qualitative evidence synthesis by Nicola Farrar, Daisy Elliott, Catherine Houghton, Marcus Jepson, Nicola Mills, Sangeetha Paramasivan, Lucy Plumb, Julia Wade, Bridget Young, Jenny L. Donovan, Leila Rooshenas

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Development of a new adapted QuinteT Recruitment Intervention (QRI-Two) for rapid application to RCTs underway with enrolment shortfalls—to identify previously hidden barriers and... by Jenny L. Donovan, Marcus Jepson, Leila Rooshenas, Sangeetha Paramasivan, Nicola Mills, Daisy Elliott, Julia Wade, Domenic Reda, Jane M. Blazeby, Drew Moghanaki, E. Shelley Hwang, Louise Davies

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What empirical research has been undertaken on the ethics of clinical research in India? A systematic scoping review and narrative synthesis by Leila Rooshenas, Jane M Blazeby, Richard Huxtable, Julia Wade, Philippa Davies, Sangeetha Paramasivan, Jonathan Ives, Jenny L Donovan, Nicola Mills, Alison Richards, Alba Realpe, Jeffrey Pradeep Raj, Supriya Subramani

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What should be included in case report forms? Development and application of novel methods to inform surgical study design: a mixed methods case study in parastomal hernia preventi... by Leila Rooshenas, Timothy Rockall, Neil Smart, Jared Torkington, Natalie S Blencowe, Jane Blazeby, Tom Pinkney, Barnaby Reeves, Charlotte Murkin, Joanne Bennett, I R Daniels, Jamshed Shabbir, Jonathan Randall, H T Brandsma

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The role of healthcare professionals’ communication in trial participation decisions: a qualitative investigation of recruitment consultations and patient interviews across three R... by Nicola Farrar, Daisy Elliott, Marcus Jepson, Bridget Young, Jenny L. Donovan, Carmel Conefrey, Alba X. Realpe, Nicola Mills, Julia Wade, Eric Lim, Robert C. Stein, Fergus J. Caskey, Leila Rooshenas

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Usability of an Automated System for Real-Time Monitoring of Shared Decision-Making for Surgery: Mixed Methods Evaluation by Christin Hoffmann, Kerry Avery, Rhiannon Macefield, Tadeáš Dvořák, Val Snelgrove, Jane Blazeby, Della Hopkins, Shireen Hickey, Ben Gibbison, Leila Rooshenas, Adam Williams, Jonathan Aning, Hilary L Bekker, Angus GK McNair

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Using clinical practice variations as a method for commissioners and clinicians to identify and prioritise opportunities for disinvestment in health care: a cross-sectional study,... by William Hollingworth, Leila Rooshenas, John Busby, Christine E Hine, Padmanabhan Badrinath, Penny F Whiting, Theresa HM Moore, Amanda Owen-Smith, Jonathan AC Sterne, Hayley E Jones, Claire Beynon, Jenny L Donovan

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Development, validation and evaluation of an instrument for active monitoring of men with clinically localised prostate cancer: systematic review, cohort studies and qualitative st... by Andrew J Simpkin, Leila Rooshenas, Julia Wade, Jenny L Donovan, J Athene Lane, Richard M Martin, Chris Metcalfe, Peter C Albertsen, Freddie C Hamdy, Lars Holmberg, David E Neal, Kate Tilling

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‘Overnight, things changed. Suddenly, we were in it’: a qualitative study exploring how surgical teams mitigated risks of COVID-19 by Leila Rooshenas, Jane M Blazeby, David Jayne, Natalie S Blencowe, Anni Skilton, Marcus Jepson, Peter Hutchinson, Sian Cousins, Daisy Elliott, Sangeetha Paramasivan, Jenny L Donovan, Cynthia Ochieng, Martin Birchall, Kerry NL Avery

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147:oral Prioritisation in the United Kingdon national health service during a national emergency: a qualitative case study of surgical teams’ experiences of colorectal cancer surg... by Leila Rooshenas, Baljit Singh, Jane Blazeby, Kerry Avery, Marcus Jepson, Natalie Blencowe, Daisy Elliott, Barry Main, David Messenger, Cynthia Ochieng, James Kinross, Carmel Conefrey, Angus McNair, Jo Bennett, Christin Hoffman, Sarah Squire, Anne Pullybank, Sarah Duff

Did the evidence-based intervention (EBI) programme reduce inappropriate procedures, lessen unwarranted variation or lead to spill-over effects in the National Health Service? by Joel Glynn, Timothy Jones, Mike Bell, Jane Blazeby, Christopher Burton, Carmel Conefrey, Jenny L. Donovan, Nicola Farrar, Josie Morley, Angus McNair, Amanda Owen-Smith, Ellen Rule, Gail Thornton, Victoria Tucker, Iestyn Williams, Leila Rooshenas, William Hollingworth

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