Human effector CD8+ T cells with an activated and exhausted-like phenotype control tumour growth in vivo in a humanized tumour modelResearch in context by Juliane Mietz, Meike Kaulfuss, Lukas Egli, Lennart Opitz, Christian Münz, Obinna Chijioke

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Individualized Pooled CRISPR/Cas9 Screenings Identify CDK2 as a Druggable Vulnerability in a Canine Mammary Carcinoma Patient by Marine Inglebert, Martina Dettwiler, Chang He, Enni Markkanen, Lennart Opitz, Arunasalam Naguleswaran, Sven Rottenberg

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Correction to: Limited utility of tissue micro-arrays in detecting intra-tumoral heterogeneity in stem cell characteristics and tumor progression markers in breast cancer by Pascale Kündig, Charlotte Giesen, Hartland Jackson, Bernd Bodenmiller, Bärbel Papassotirolopus, Sandra Nicole Freiberger, Catharine Aquino, Lennart Opitz, Zsuzsanna Varga

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Transcriptome profiles of latently- and reactivated HIV-1 infected primary CD4+ T cells: A pooled data-analysis by Anne Inderbitzin, Anne Inderbitzin, Anne Inderbitzin, Tom Loosli, Tom Loosli, Tom Loosli, Lennart Opitz, Peter Rusert, Karin J. Metzner, Karin J. Metzner

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Large-Scale Integrative Analysis of Epigenetic Modifications Induced by Isotretinoin, Doxycycline and Metronidazole in Murine Colonic Intestinal Epithelial Cells by Eugenia Becker, Susan Bengs, Sirisha Aluri, Lennart Opitz, Kirstin Atrott, Felix Rost, Irina Leonardi, Claudia Stanzel, Tina Raselli, Stephanie Kasper, Pedro A. Ruiz, Gerhard Rogler

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Transcriptomic and proteomic profiling identifies feline fibrosarcoma as clinically amenable model for aggressive sarcoma subtypes by Mikiyo Weber, Daniel Fuchs, Amiskwia Pöschel, Erin Beebe, Zuzana Garajova, Armin Jarosch, Laura Kunz, Witold Wolski, Lennart Opitz, Franco Guscetti, Mirja C. Nolff, Enni Markkanen

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Concurrent Activation of Both Survival-Promoting and Death-Inducing Signaling by Chloroquine in Glioblastoma Stem Cells: Implications for Potential Risks and Benefits of Using Chlo... by Andreas Müller, Patrick Weyerhäuser, Nancy Berte, Fitriasari Jonin, Bogdan Lyubarskyy, Bettina Sprang, Sven Rainer Kantelhardt, Gabriela Salinas, Lennart Opitz, Walter Schulz-Schaeffer, Alf Giese, Ella L. Kim

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Intrabiliary infusion of naked DNA vectors targets periportal hepatocytes in mice by Sereina Deplazes, Andrea Schlegel, Zhuolun Song, Gabriella Allegri, Nicole Rimann, Tanja Scherer, Melanie Willimann, Lennart Opitz, Sharon C. Cunningham, Ian E. Alexander, Anja Kipar, Johannes Häberle, Beat Thöny, Hiu Man Grisch-Chan

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Large-scale microRNA functional high-throughput screening identifies miR-515-3p and miR-519e-3p as inducers of human cardiomyocyte proliferation by Harsha V. Renikunta, Katina Lazarow, Yiqi Gong, Praphulla Chandra Shukla, Vanasa Nageswaran, Hector Giral, Adelheid Kratzer, Lennart Opitz, Felix B. Engel, Arash Haghikia, Sarah Costantino, Francesco Paneni, Jens Peter von Kries, Katrin Streckfuss-Bömeke, Ulf Landmesser, Philipp Jakob

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Transcriptional profile of Mycobacterium tuberculosis infection in people living with HIV by Burcu Tepekule, Lisa Jörimann, Corinne D. Schenkel, Lennart Opitz, Jasmin Tschumi, Rebekka Wolfensberger, Kathrin Neumann, Katharina Kusejko, Marius Zeeb, Lucas Boeck, Marisa Kälin, Julia Notter, Hansjakob Furrer, Matthias Hoffmann, Hans H. Hirsch, Alexandra Calmy, Matthias Cavassini, Niklaus D. Labhardt, Enos Bernasconi, Gabriela Oesch, Karin J. Metzner, Dominique L. Braun, Huldrych F. Günthard, Roger D. Kouyos, Fergal Duffy, Johannes Nemeth

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Lymphadenopathy driven by TCR-Vγ8Vδ1 T-cell expansion in FAS-related autoimmune lymphoproliferative syndrome by Stefano Vavassori, Jacob D. Galson, Johannes Trück, Anke van den Berg, Rienk Y.J. Tamminga, Aude Magerus-Chatinet, Olivier Pellé, Ulrike Camenisch Gross, Ewerton Marques Maggio, Seraina Prader, Lennart Opitz, Ursina Nüesch, Andrea Mauracher, Benjamin Volkmer, Oliver Speer, Luzia Suda, Benno Röthlisberger, Dieter Robert Zimmermann, Rouven Müller, Arjan Diepstra, Lydia Visser, Eugenia Haralambieva, Bénédicte Neven, Frédéric Rieux-Laucat, Jana Pachlopnik Schmid

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