The Impact of Tumor Heterogeneity on Diagnostics and Novel Therapeutic Strategies in Multiple Myeloma by Leo Rasche, K. Martin Kortüm, Marc S. Raab, Niels Weinhold

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Toxicities of Chimeric Antigen Receptor T Cell Therapy in Multiple Myeloma: An Overview of Experience From Clinical Trials, Pathophysiology, and Management Strategies by Xiang Zhou, Leo Rasche, K. Martin Kortüm, Sophia Danhof, Michael Hudecek, Hermann Einsele

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The natural human IgM antibody PAT-SM6 induces apoptosis in primary human multiple myeloma cells by targeting heat shock protein GRP78. by Leo Rasche, Johannes Duell, Charlotte Morgner, Manik Chatterjee, Frank Hensel, Andreas Rosenwald, Hermann Einsele, Max S Topp, Stephanie Brändlein

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Erdheim-Chester disease with Rosai-Dorfman-like lesions: treatment with methotrexate, anakinra and upadacitinib by Andreas Rosenwald, Marc Schmalzing, Matthias Fröhlich, Jan Portegys, Anke Heidemeier, Michael Gernert, Sebastian Hueper, Patrick Pascal Strunz, Leo Rasche

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Clinical and Biological Characteristics of Medullary and Extramedullary Plasma Cell Dyscrasias by Snjezana Janjetovic, Philipp Lohneis, Axel Nogai, Derya Balci, Leo Rasche, Doris Jähne, Carsten Bokemeyer, Georgia Schilling, Igor Wolfgang Blau, Martin Schmidt-Hieber

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Multiagent therapy with pomalidomide, bortezomib, doxorubicin, dexamethasone, and daratumumab (“Pom‐PAD‐Dara”) in relapsed/refractory multiple myeloma by Xiang Zhou, Maximilian J. Steinhardt, Denise Grathwohl, Katharina Meckel, Katharina Nickel, Hans‐Benno Leicht, Franziska Krummenast, Hermann Einsele, Leo Rasche, Klaus M. Kortüm

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Extramedullary disease in multiple myeloma: a systematic literature review by Joan Bladé, Meral Beksac, Jo Caers, Artur Jurczyszyn, Marie von Lilienfeld-Toal, Philippe Moreau, Leo Rasche, Laura Rosiñol, Saad Z. Usmani, Elena Zamagni, Paul Richardson

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Adverse effects and non-relapse mortality of BCMA directed T cell therapies in multiple myeloma: an FAERS database study by Zimu Gong, Godsfavour Umoru, Jorge Monge, Nishi Shah, Ghulam Rehman Mohyuddin, Sabarinath Venniyil Radhakrishnan, Rajshekhar Chakraborty, Leo Rasche, Carolina Schinke, Anita D’Souza, Meera Mohan

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P836: ANTIBODY-DRUG CONJUGATES AS POTENTIAL CAR-T CELL SPECIFIC OFF-SWITCH IN MULTIPLE MYELOMA by Anna Bielowski, Teresa Kilian, Sarah Rümpeler Calheiros Vera-Cruz, Zeno Riester, Sabrina Prommersberger, Julia Beckmann, Martin Kortüm, Leo Rasche, Hermann Einsele, Michael Hudecek, Sophia Danhof

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Patient selection for CAR T or BiTE therapy in multiple myeloma: Which treatment for each patient? by David Kegyes, Catalin Constantinescu, Louise Vrancken, Leo Rasche, Celine Gregoire, Bogdan Tigu, Diana Gulei, Delia Dima, Alina Tanase, Hermann Einsele, Stefan Ciurea, Ciprian Tomuleasa, Jo Caers

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Gene Expression Profiling in Multiple Myeloma: Redefining the Paradigm of Risk-Adapted Treatment by Claudio Cerchione, Saad Z. Usmani, A. Keith Stewart, Martin Kaiser, Martin Kaiser, Leo Rasche, Martin Kortüm, María-Victoria Mateos, Andrew Spencer, Pieter Sonneveld, Kenneth C. Anderson

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P814: ANALYSIS OF TP53 ALTERATIONS BY WGS REVEALS BIALLELIC 17P DELETIONS IN MULTIPLE MYELOMA by Marietta Truger, Stephan Hutter, Wencke Walter, Xiang Zhou, Christine Riedhammer, Manja Meggendorfer, Heiko Müller, Wolfgang Kern, Torsten Haferlach, Hermann Einsele, K Martin Kortum, Claudia Haferlach, Leo Rasche

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Carfilzomib Based Treatment Strategies in the Management of Relapsed/Refractory Multiple Myeloma with Extramedullary Disease by Xiang Zhou, Patricia Flüchter, Katharina Nickel, Katharina Meckel, Janin Messerschmidt, David Böckle, Sebastian Knorz, Maximilian Johannes Steinhardt, Franziska Krummenast, Sophia Danhof, Hermann Einsele, K. Martin Kortüm, Leo Rasche

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Lymphocyte and neutrophil count combined with intestinal bacteria abundance predict the severity of COVID-19 by Liuying Chen, Zhongwei Yin, Dan Zhou, Xin Li, Cheng Yu, Chang Luo, Yu Jin, Lei Zhang, Jun Song, Leo Rasche, Hermann Einsele, Lei Tu, Xiang Zhou, Tao Bai, Xiaohua Hou

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¹⁸F-FDG and ¹¹C-Methionine PET/CT in Newly Diagnosed Multiple Myeloma Patients: Comparison of Volume-Based PET Biomarkers by Maria I Morales-Lozano, Oliver Viering, Samuel Samnick, Paula Rodriguez-Otero, Andreas K Buck, Maria Marcos-Jubilar, Leo Rasche, Elena Prieto, K Martin Kortüm, Jesus San-Miguel, Maria J. Garcia-Velloso, Constantin Lapa

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18F-FDG, 11C-Methionine, and 68Ga-Pentixafor PET/CT in Patients with Smoldering Multiple Myeloma: Imaging Pattern and Clinical Features by Xiang Zhou, Alexander Dierks, Olivia Kertels, Malte Kircher, Andreas Schirbel, Samuel Samnick, Andreas K. Buck, Sebastian Knorz, David Böckle, Lukas Scheller, Janin Messerschmidt, Mohammad Barakat, K. Martin Kortüm, Leo Rasche, Hermann Einsele, Constantin Lapa

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Reliable and Interpretable Mortality Prediction With Strong Foresight in COVID-19 Patients: An International Study From China and Germany by Tao Bai, Xue Zhu, Xiang Zhou, Denise Grathwohl, Pengshuo Yang, Yuguo Zha, Yu Jin, Hui Chong, Qingyang Yu, Nora Isberner, Dongke Wang, Lei Zhang, K. Martin Kortüm, Jun Song, Leo Rasche, Hermann Einsele, Kang Ning, Xiaohua Hou

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The Link between Cytogenetics/Genomics and Imaging Patterns of Relapse and Progression in Patients with Relapsed/Refractory Multiple Myeloma: A Pilot Study Utilizing 18F-FDG PET/CT by Xiang Zhou, Alexander Dierks, Olivia Kertels, Samuel Samnick, Malte Kircher, Andreas K. Buck, Larissa Haertle, Sebastian Knorz, David Böckle, Lukas Scheller, Janin Messerschmidt, Mohammad Barakat, Marietta Truger, Claudia Haferlach, Hermann Einsele, Leo Rasche, K. Martin Kortüm, Constantin Lapa

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The spatio-temporal evolution of multiple myeloma from baseline to relapse-refractory states by Leo Rasche, Carolina Schinke, Francesco Maura, Michael A. Bauer, Cody Ashby, Shayu Deshpande, Alexandra M. Poos, Maurizio Zangari, Sharmilan Thanendrarajan, Faith E. Davies, Brian A. Walker, Bart Barlogie, Ola Landgren, Gareth J. Morgan, Frits van Rhee, Niels Weinhold

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P890: COMBINING SKY92 GENE EXPRESSION PROFILING WITH CYTOGENETICS ACCORDING TO R2-ISS FOR MULTIPLE MYELOMA RISK CLASSIFICATION: THE FIRST PROSPECTIVE EVIDENCE by Xiang Zhou, Benedict Engel, Annika Hofmann, Cornelia Vogt, Silvia Nerreter, Eva Teufel, Emilia Stanojkovska, Marietta Truger, Philipp Weis, Xianghui Xiao, Florian Eisele, Christine Riedhammer, Maximilian Johannes Steinhardt, Umair Munawar, Seungbin Han, Larissa Haertle, Claudia Haferlach, Hermann Einsele, K Martin Kortum, Leo Rasche

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