Comparison of ALitretinoin with PUVA as the first-line treatment in patients with severe chronic HAnd eczema (ALPHA): study protocol for a randomised controlled trial by Catherine Smith, Miriam Wittmann, Fiona Cowdell, Sarah Brown, Catherine Reynolds, Catherine Fernandez, Sandy Tubeuf, Jane Nixon, Rachael Gilberts, Mark Goodfield, Isabelle L Smith, John T Lear, Lesley Sunderland, Cathy Green, Philip Hampton, Amy Barker, Armando Vargas-Palacios

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