Rapid Optimization of Mcl-1 Inhibitors using Stapled Peptide Libraries Including Non-Natural Side Chains by Letai, Anthony, Rezaei Araghi, Raheleh, Ryan, Jeremy Adam, Keating, Amy E.

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Potent and Specific Peptide Inhibitors of Human Pro-Survival Protein Bcl-xL by Ryan, Jeremy, Letai, Anthony, Dutta, Sanjib, Chen, T. Scott, Kougentakis, Christos, Keating, Amy E.

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Designed BH3 Peptides with High Affinity and Specificity for Targeting Mcl-1 in Cells by Ryan, Jeremy A., Letai, Anthony, Foight, Glenna W., Gulla, Stefano V., Keating, Amy E.

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Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1 by Ryan, Jeremy A., Letai, Anthony, Jenson, Justin Michael, Grant, Robert A., Keating, Amy E.

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Iterative optimization yields Mcl-1–targeting stapled peptides with selective cytotoxicity to Mcl-1–dependent cancer cells by Bird, Gregory H., Ryan, Jeremy A., Godes, Marina, Pritz, Jonathan R., Letai, Anthony, Walensky, Loren D., Rezaei Araghi, Raheleh, Jenson, Justin Michael, Grant, Robert A, Keating, Amy E.

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Mitochondrial apoptotic priming is a key determinant of cell fate upon p53 restoration by Sánchez-Rivera, Francisco J, Ryan, Jeremy, Soto-Feliciano, Yadira M, Clare Beytagh, Mary, Xuan, Lucius, Feldser, David M, Hemann, Michael T, Zamudio, Jesse, Dimitrova, Nadya, Letai, Anthony, Jacks, Tyler

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Aneuploidy increases resistance to chemotherapeutics by antagonizing cell division by Replogle, John Michael, Zhou, Wen, Amaro, Adrianna E, McFarland, James M, Villalobos-Ortiz, Mariana, Ryan, Jeremy, Letai, Anthony, Yilmaz, Omer, Sheltzer, Jason, Lippard, Stephen J, Ben-David, Uri, Amon, Angelika

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Synergistic interactions with PI3K inhibition that induce apoptosis by Zwang, Yaara, Chen, Casandra, Rinne, Mikael L, Doench, John G, Piccioni, Federica, Tan, Li, Huang, Hai-Tsang, Wang, Jinhua, Ham, Young Jin, O'Connell, Joyce, Bhola, Patrick, Doshi, Mihir, Whitman, Matthew, Letai, Anthony, Root, David E, Gray, Nathanael, Hahn, William C, Jonas, Oliver H., Langer, Robert S, Cima, Michael J.

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Multiple screening approaches reveal HDAC6 as a novel regulator of glycolytic metabolism in triple-negative breast cancer by Dowling, Catríona M, Hollinshead, Kate ER, Di Grande, Alessandra, Pritchard, Justin, Zhang, Hua, Dillon, Eugene T, Haley, Kathryn, Papadopoulos, Eleni, Mehta, Anita K, Bleach, Rachel, Lindner, Andreas U, Mooney, Brian, Düssmann, Heiko, O’Connor, Darran, Prehn, Jochen HM, Wynne, Kieran, Hemann, Michael, Bradner, James E, Kimmelman, Alec C, Guerriero, Jennifer L, Cagney, Gerard, Wong, Kwok-Kin, Letai, Anthony G, Chonghaile, Tríona Ní

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Multiple screening approaches reveal HDAC6 as a novel regulator of glycolytic metabolism in triple-negative breast cancer by Dowling, Catríona M., Hollinshead, Kate E. R., Di Grande, Alessandra, Pritchard, Justin, Zhang, Hua, Dillon, Eugene T., Haley, Kathryn, Papadopoulos, Eleni, Mehta, Anita K., Bleach, Rachel, Lindner, Andreas U., Mooney, Brian, Düssmann, Heiko, O’Connor, Darran, Prehn, Jochen H. M., Wynne, Kieran, Hemann, Michael, Bradner, James E., Kimmelman, Alec C., Guerriero, Jennifer L., Cagney, Gerard, Wong, Kwok-Kin, Letai, Anthony G., Chonghaile, Tríona Ní

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