Selective Killing of K-ras Mutant Cancer Cells by Novel Small Molecule Inducers of Oxidative Stress by Shaw, Alice, Winslow, Monte Meier, Magendantz, Margaret, Ouyang, Chensi, Dowdle, James, Subramanian, Aravind, Lewis, Timothy A., Maglathin, Rebecca L., Tolliday, Nicola, Jacks, Tyler E

Get full text
Get full text

Chemical perturbation of an intrinsically disordered region of TFIID distinguishes two modes of transcription initiation by Zhang, Zhengjian, Boskovic, Zarko, Hu, Wenxin, Inouye, Carla, Kim, Han-Je, Tjian, Robert, Hussain, Mahmud M., Abole, A. Katherine, Doud, Mary K., Lewis, Timothy A., Koehler, Angela Nicole, Schreiber, Stuart L.

Get full text

A Small Molecule That Binds and Inhibits the ETV1 Transcription Factor Oncoprotein by Pop, Marius S., Stransky, Nicolas, Garvie, Colin W., Theurillat, Jean-Philippe, Hartman, Emily C., Lewis, Timothy A., Zhong, Cheng, Culyba, Elizabeth K., Lin, Fallon, Daniels, Douglas S., Pagliarini, Raymond, Ronco, Lucienne, Koehler, Angela Nicole, Garraway, Levi A.

Get full text

Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells by Kubicek, Stefan, Gilbert, Joshua C., Fomina-Yadlin, Dina, Gitlin, Alexander D., Yuan, Yuan, Wagner, Florence F., Holson, Edward B., Luo, Tuoping, Lewis, Timothy A., Taylor, Bradley, Gupta, Supriya, Shamji, Alykhan F., Wagner, Bridget K., Clemons, Paul A., Schreiber, Stuart L.

Get full text

A Mitotic Phosphorylation Feedback Network Connects Cdk1, Plk1, 53BP1, and Chk2 to Inactivate the G2/M DNA Damage Checkpoint by Yaffe, Michael B., Brummelkamp, Thijn R., Reinhardt, Hans, Ostheimer, Gerard, Gardino, Alexandra Kate, van Vugt, Marcel A. T. M., Smerdon, Stephen J., Carr, Steven A., Lewis, Timothy A., Pawson, Tony, Li, Jeijin, Keezer, Susan M., Miao, Hua, Tan, Chris S., Ong, Shao-En, Linding, Rune

Get full text
Get full text
Get full text

Indolinyl-Thiazole Based Inhibitors of Scavenger Receptor-BI (SR-BI)-Mediated Lipid Transport by Dockendorff, Chris, Faloon, Patrick W., Youngsaye, Willmen, Nag, Partha P., Lewis, Timothy A., Pu, Jun, Bennion, Melissa, Negri, Joseph, Paterson, Conor, Lam, Garrett, Dandapani, Sivaraman, Perez, José R., Munoz, Benito, Palmer, Michelle A., Schreiber, Stuart L., Yu, Miao, Penman, Marsha L, Nieland, Thomas J, Krieger, Monty

Get full text
Get full text
Get full text

Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics by de Waal, Luc, Lewis, Timothy A, Rees, Matthew G, Tsherniak, Aviad, Wu, Xiaoyun, Choi, Peter S, Gechijian, Lara, Hartigan, Christina, Faloon, Patrick W, Hickey, Mark J, Tolliday, Nicola, Carr, Steven A, Clemons, Paul A, Munoz, Benito, Wagner, Bridget K, Shamji, Alykhan F, Schenone, Monica, Burgin, Alex B, Schreiber, Stuart L, Greulich, Heidi, Meyerson, Matthew, Koehler, Angela Nicole

Get full text

Stabilization of the Max Homodimer with a Small Molecule Attenuates Myc-Driven Transcription by Struntz, Nicholas B., Chen, Andrew I, Deutzmann, Anja, Wilson, Robert M., Stefan, Eric, Evans, Helen L, Ramirez, Maricela A., Liang, Tong, Caballero, Francisco, Wildschut, Mattheus H.E., Neel, Dylan V, Freeman, David B., Pop, Marius S, McConkey, Marie, Muller, Sandrine, Curtin, Brice Harrison, Tseng, Hanna, Frombach, Kristen R., Butty, Vincent L G, Levine, Stuart S., Feau, Clementine, Elmiligy, Sarah, Hong, Jiyoung A., Lewis, Timothy A., Vetere, Amedeo, Clemons, Paul A., Malstrom, Scott E., Ebert, Benjamin L., Lin, Charles Y., Felsher, Dean W., Koehler, Angela Nicole

Get full text