Antiviral lectin Q-Griffithsin suppresses fungal infection in murine models of vaginal candidiasis by Henry W. Nabeta, Henry W. Nabeta, Amanda B. Lasnik, Joshua L. Fuqua, Joshua L. Fuqua, Lin Wang, Lisa C. Rohan, Lisa C. Rohan, Lisa C. Rohan, Kenneth E. Palmer, Kenneth E. Palmer, Kenneth E. Palmer

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Tenofovir vaginal film as a potential MPT product against HIV-1 and HSV-2 acquisition: formulation development and preclinical assessment in non-human primates by Sravan Kumar Patel, Sravan Kumar Patel, Hrushikesh Agashe, Hrushikesh Agashe, Dorothy L. Patton, Yvonne Sweeney, May A. Beamer, Craig W. Hendrix, Sharon L. Hillier, Sharon L. Hillier, Lisa C. Rohan, Lisa C. Rohan, Lisa C. Rohan

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2519 by Sheila Grab, Yvonne Cosgrove Sweeney, Dorothy L. Patton, Lisa C. Rohan

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Design of Poly(lactic-<i>co</i>-glycolic Acid) (PLGA) Nanoparticles for Vaginal Co-Delivery of Griffithsin and Dapivirine and Their Synergistic Effect for HIV Prophylaxis by Haitao Yang, Jing Li, Sravan Kumar Patel, Kenneth E. Palmer, Brid Devlin, Lisa C. Rohan

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Label-free analysis of tenofovir delivery to vaginal tissue using co-registered confocal Raman spectroscopy and optical coherence tomography. by Oranat Chuchuen, Jason R Maher, Marcus H Henderson, Michael Desoto, Lisa C Rohan, Adam Wax, David F Katz

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Transport and Permeation Properties of Dapivirine: Understanding Potential Drug-Drug Interactions by Ruohui Zheng, Guru R. Valicherla, Junmei Zhang, Jeremy Nuttall, Peter Silvera, Leslie J. Marshall, Philip E. Empey, Lisa C. Rohan

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Development of HIV-1 rectal-specific microbicides and colonic tissue evaluation. by Charlene S Dezzutti, Julie Russo, Lin Wang, Kaleab Z Abebe, Jie Li, David R Friend, Ian M McGowan, Lisa C Rohan

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A compensatory mutation provides resistance to disparate HIV fusion inhibitor peptides and enhances membrane fusion. by Matthew P Wood, Amy L Cole, Piotr Ruchala, Alan J Waring, Lisa C Rohan, Preston Marx, Patrick M Tarwater, Phalguni Gupta, Alexander M Cole

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Development and Evaluation of Nanoparticles-in-Film Technology to Achieve Extended In Vivo Exposure of MK-2048 for HIV Prevention by Xin Tong, Sravan Kumar Patel, Jing Li, Dorothy Patton, Elaine Xu, Peter L. Anderson, Urvi Parikh, Yvonne Sweeney, Julie Strizki, Sharon L. Hillier, Lisa C. Rohan

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Development, Characterization and In Vivo Pharmacokinetic Assessment of Rectal Suppositories Containing Combination Antiretroviral Drugs for HIV Prevention by Kunal Jhunjhunwala, Charles W. Dobard, Sunita Sharma, Natalia Makarova, Angela Holder, Chuong Dinh, James Mitchell, Lin Wang, Junmei Zhang, Sravan Kumar Patel, Walid Heneine, Lisa C. Rohan

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Is wetter better? An evaluation of over-the-counter personal lubricants for safety and anti-HIV-1 activity. by Charlene S Dezzutti, Elizabeth R Brown, Bernard Moncla, Julie Russo, Marilyn Cost, Lin Wang, Kevin Uranker, Ratiya P Kunjara Na Ayudhya, Kara Pryke, Jim Pickett, Marc-André Leblanc, Lisa C Rohan

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A topical rectal douche product containing Q-Griffithsin does not disrupt the epithelial border or alter CD4+ cell distribution in the human rectal mucosa by Mathias Franzén Boger, Nora Benhach, Tyra Hasselrot, Rhonda M. Brand, Lisa C. Rohan, Lin Wang, Ian McGowan, Stacey Edick, Ken Ho, Leslie Meyn, Nobuyuki Matoba, Kenneth E. Palmer, Kristina Broliden, Annelie Tjernlund

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Hypo-osmolar rectal douche tenofovir formulation prevents simian/human immunodeficiency virus acquisition in macaques by Peng Xiao, Sanjeev Gumber, Mark A. Marzinke, Thuy Hoang, Rohan Myers, Abhijit A. Date, Justin Hanes, Laura M. Ensign, Lin Wang, Lisa C. Rohan, Richard Cone, Edward J. Fuchs, Craig W. Hendrix, Francois Villinger

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In vitro and ex vivo testing of tenofovir shows it is effective as an HIV-1 microbicide. by Lisa C Rohan, Bernard J Moncla, Ratiya Pamela Kunjara Na Ayudhya, Marilyn Cost, Yunda Huang, Fang Gai, Nicole Billitto, J D Lynam, Kara Pryke, Phillip Graebing, Nicole Hopkins, James F Rooney, David Friend, Charlene S Dezzutti

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The formulated microbicide RC-101 was safe and antivirally active following intravaginal application in pigtailed macaques. by Alexander M Cole, Dorothy L Patton, Lisa C Rohan, Amy L Cole, Yvonne Cosgrove-Sweeney, Nicole A Rogers, Deena Ratner, Alexandra B Sassi, Carol Lackman-Smith, Patrick Tarwater, Bharat Ramratnam, Piotr Ruchala, Robert I Lehrer, Alan J Waring, Phalguni Gupta

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A Phase 1 Randomized, Open Label, Rectal Safety, Acceptability, Pharmacokinetic, and Pharmacodynamic Study of Three Formulations of Tenofovir 1% Gel (the CHARM-01 Study). by Ian Mcgowan, Ross D Cranston, Kathryn Duffill, Aaron Siegel, Jarret C Engstrom, Alexyi Nikiforov, Cindy Jacobson, Khaja K Rehman, Julie Elliott, Elena Khanukhova, Kaleab Abebe, Christine Mauck, Hans M L Spiegel, Charlene S Dezzutti, Lisa C Rohan, Mark A Marzinke, Hiwot Hiruy, Craig W Hendrix, Nicola Richardson-Harman, Peter A Anton

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Cryopreservation of human mucosal tissues. by Sean M Hughes, April L Ferre, Sarah E Yandura, Cory Shetler, Chris A R Baker, Fernanda Calienes, Claire N Levy, Rena D Astronomo, Zhiquan Shu, Gretchen M Lentz, Michael Fialkow, Anna C Kirby, M Juliana McElrath, Elizabeth Sinclair, Lisa C Rohan, Peter L Anderson, Barbara L Shacklett, Charlene S Dezzutti, Dayong Gao, Florian Hladik

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