Cell and tissue specific functional genomics of psoriasis and psoriatic arthritis od Lledo Lara, A

Ex vivo mass cytometry analysis reveals a profound myeloid proinflammatory signature in psoriatic arthritis synovial fluid od Yager, N, Cole, S, Lledo Lara, A, Maroof, A, Penkava, F, Knight, JC, Bowness, P, Al-Mossawi, H

Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis od Penkava, F, Del Castillo Velasco-Herrera, M, Young, M, Yager, N, Nwosu, L, Pratt, A, Lledo Lara, A, Guzzo, C, Mamanova, L, Cole, S, Efremova, M, Simone, D, Filer, A, Brown, C, Croxford, A, Isaacs, J, Teichmann, S, Bowness, P, Behjati, S, Al-Mossawi, M

Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis od Brown, AC, Cohen, CJ, Mielczarek, O, Migliorini, G, Costantino, F, Allcock, A, Davidson, C, Elliott, KS, Fang, H, Lledó Lara, A, Martin, AC, Osgood, JA, Sanniti, A, Scozzafava, G, Vecellio, M, Zhang, P, Black, MH, Li, S, Truong, D, Molineros, J, Howe, T, Wordsworth, BP, Bowness, P, Knight, JC

A genetics-led approach defines the drug target landscape of 30 immune-related traits od Fang, H, De Wolf, H, Knezevic, B, Burnham, K, Osgood, J, Sanniti, A, Lledó Lara, A, Kasela, S, De Cesco, S, Wegner, J, Handunnetthi, L, McCann, F, Chen, L, Sekine, T, Brennan, P, Marsden, B, Damerell, D, O’Callaghan, C, Bountra, C, Bowness, P, Sundström, Y, Milani, L, Berg, L, Göhlmann, H, Peeters, P, Fairfax, B, Sundström, M, Knight, J