Lipids on trial: the search for the offending metabolite in Niemann-Pick type C disease. by Lloyd-Evans, E, Platt, F

Lysosomal Ca(2+) homeostasis: role in pathogenesis of lysosomal storage diseases. by Lloyd-Evans, E, Platt, F

LYSOSOMAL SPHINGOSINE STORAGE INDUCED BY MYCOLIC ACID MEDIATED INHIBITION OF THE NPC1 PROTEIN IS CENTRAL TO Mycobacterium tuberculosis INDUCED PATHOGENESIS by Lloyd-Evans, E, Fineran, P, Platt, F

Molecular mechanisms of endolysosomal Ca2+ signalling in health and disease. by Morgan, A, Platt, F, Lloyd-Evans, E, Galione, A

Endolysosomal calcium regulation and disease. by Lloyd-Evans, E, Waller-Evans, H, Peterneva, K, Platt, F

Inhibition of phago-lysosome fusion and foam cell formation by Mycobacterium bovis BCG induces a Niemann-Pick type C1 like phenotype by Lloyd-Evans, E, Lack, N, Williams, I, Churchill, G, Sim, E, Platt, F

Inhibition of calcium uptake via the sarco/endoplasmic reticulum Ca2+-ATPase in a mouse model of Sandhoff disease and prevention by treatment with N-butyldeoxynojirimycin. by Pelled, D, Lloyd-Evans, E, Riebeling, C, Jeyakumar, M, Platt, F, Futerman, A

Accumulation of glycosphingolipids in Niemann-Pick C disease disrupts endosomal transport. by te Vruchte, D, Lloyd-Evans, E, Veldman, R, Neville, D, Dwek, R, Platt, F, van Blitterswijk, W, Sillence, D

Treatment with miglustat reverses the lipid-trafficking defect in Niemann-Pick disease type C. by Lachmann, R, te Vruchte, D, Lloyd-Evans, E, Reinkensmeier, G, Sillence, D, Fernandez-Guillen, L, Dwek, R, Butters, T, Cox, T, Platt, F

Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium. by Lloyd-Evans, E, Morgan, A, He, X, Smith, D, Elliot-Smith, E, Sillence, D, Churchill, G, Schuchman, E, Galione, A, Platt, F

Beneficial effects of substrate reduction therapy in a mouse model of GM1 gangliosidosis. by Elliot-Smith, E, Speak, A, Lloyd-Evans, E, Smith, D, van der Spoel, A, Jeyakumar, M, Butters, T, Dwek, R, d'Azzo, A, Platt, F

Purified TPC isoforms form NAADP receptors with distinct roles for Ca(2+) signaling and endolysosomal trafficking. by Ruas, M, Rietdorf, K, Arredouani, A, Davis, L, Lloyd-Evans, E, Koegel, H, Funnell, T, Morgan, A, Ward, J, Watanabe, K, Cheng, X, Churchill, G, Zhu, M, Platt, F, Wessel, G, Parrington, J, Galione, A

Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway by Fineran, P, Lloyd-Evans, E, Lack, N, Platt, N, Davis, L, Morgan, A, Höglinger, D, Tatituri, R, Clark, S, Williams, I, Tynan, P, Al Eisa, N, Nazarova, E, Williams, A, Galione, A, Ory, D, Besra, G, Russell, D, Brenner, M, Sim, E, Platt, F