Polygenic risk scores for complex diseases: where are we now? by Loh, Marie, Chambers, John Campbell

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Contribution of lower physical activity levels to higher risk of insulin resistance and associated metabolic disturbances in South Asians compared to Europeans by Afaq, Saima, Kooner, Angad S., Loh, Marie, Kooner, Jaspal S., Chambers, John Campbell

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Active collaboration with primary care providers increases specialist referral in chronic renal disease by Loh Marie, Zhu Ai-Ling, Mondry Adrian, Vo Thuy D, Hahn Kai

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Investigating causal relationships between Body Mass Index and risk of atopic dermatitis : a Mendelian randomization analysis by Yew, Yik Weng, Loh, Marie, Thng, Steven Tien Guan, Chambers, John Campbell

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Comprehensive profiling of DNA methylation in colorectal cancer reveals subgroups with distinct clinicopathological and molecular features by Vaithilingam Aparna, Grieu Fabienne, Lim Pei, Liem Natalia, Loh Marie, Ang Pei, Platell Cameron, Yong Wei, Iacopetta Barry, Soong Richie

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Genetic factors associated with intestinal metaplasia in a high risk Singapore-Chinese population: a cohort study by Salto-Tellez Manuel, Lai Kin, Koh King, Lee Sumarlin, Hill Jeffrey, Loh Marie, Zhu Feng, Iacopetta Barry, Yeoh Khay, Soong Richie

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Systematic evaluation of library preparation methods and sequencing platforms for high-throughput whole genome bisulfite sequencing by Schuster, Stephan C., Beck, Stephan, Kim, Changhoon, Chambers, John Campbell, Loh, Marie, Zhou, Li, Ng, Hong Kiat, Drautz-Moses, Daniela I.

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Investigating causal relationships between obesity and skin barrier function in a multi-ethnic Asian general population cohort by Yew, Yik Weng, Mina, Theresia, Ng, Hong Kiat, Lam, Benjamin Chih Chiang, Riboli, Elio, Lee, Eng Sing, Lee, Jimmy, Ngeow, Joanne, Elliott, Paul, Thng, Steven Tien Guan, Chambers, John Campbell, Loh, Marie

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Impact of BMI and waist circumference on epigenome-wide DNA methylation and identification of epigenetic biomarkers in blood : an EWAS in multi-ethnic Asian individuals by Chen, Yuqing, Kassam, Irfahan, Lau, Suk Hiang, Kooner, Jaspal S., Wilson, Rory, Peters, Annette, Winkelmann, Juliane, Chambers, John C., Chow, Vincent T., Khor, Chiea Chuen, Van Dam, Rob M., Teo, Yik-Ying, Loh, Marie, Sim, Xueling

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Smokeless and combustible tobacco use among 148,944 South Asian adults: a cross-sectional study of South Asia Biobank by Xie, Wubin, Mridha, Malay Kanti, Gupta, Anaya, Kusuma, Dian, Butt, Awais Muhammad, Hasan, Mehedi, Brage, Soren, Loh, Marie, Khawaja, Khadija Irfan, Pradeepa, Rajendra, Jha, Vinita, Kasturiratne, Anuradhani, Katulanda, Prasad, Anjana, Ranjit Mohan, Chambers, John Campbell

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Adiposity impacts cognitive function in Asian populations: an epidemiological and Mendelian Randomization study by Mina, Theresia, Yew, Yik Weng, Ng, Hong Kiat, Sadhu, Nilanjana, Wansaicheong, Gervais, Dalan, Rinkoo, Low, Dorrain Yan Wen, Lam, Benjamin Chih Chiang, Riboli, Elio, Lee, Eng Sing, Ngeow, Joanne, Elliott, Paul, Griva, Konstadina, Loh, Marie, Lee, Jimmy, Chambers, John

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Reversal of Phenotypic Abnormalities by CRISPR/Cas9-Mediated Gene Correction in Huntington Disease Patient-Derived Induced Pluripotent Stem Cells by Augustine, George James, Pouladi, Mahmoud A., Xu, Xiaohong, Tay, Yilin, Sim, Bernice, Yoon, Su-In, Huang, Yihui, Ooi, Jolene, Utami, Kagistia Hana, Ziaei, Amin, Ng, Bryan, Radulescu, Carola, Low, Donovan, Ng, Alvin Yu Jin, Loh, Marie, Venkatesh, Byrappa, Ginhoux, Florent

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Investigation into the origins of an ancient BRCA1 founder mutation identified among Chinese families in Singapore by Shaw, Tarryn, Chan, Sock Hoai, Teo, Jing Xian, Chong, Siao Ting, Li, Shao-Tzu, Courtney, Eliza, Ishak, Diana, Sankar, Haresh, Ang, Zoe Li Ting, Chiang, Jianbang, Loh, Marie, Zhou, Li, Lee, Soo Chin, Yeh, Hui-Yuan, Kolinjivadi, Arun Mouli, Lim, Weng Khong, Ngeow, Joanne

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The iHealth-T2D study: a cluster randomised trial for the prevention of type 2 diabetes amongst South Asians with central obesity and prediabetes-a statistical analysis plan by Muilwijk, Mirthe, Loh, Marie, Mahmood, Sara, Palaniswamy, Saranya, Siddiqui, Samreen, Silva, Wnurinham, Frost, Gary S., Gage, Heather M., Jarvelin, Marjo-Riitta, Rannan-Eliya, Ravindra P., Ahmad, Sajjad, Jha, Sujeet, Kasturiratne, Anuradhani, Katulanda, Prasad, Khawaja, Khadija I., Kooner, Jaspal S., Wickremasinghe, Ananda R., van Valkengoed, Irene G. M., Chambers, John Campbell

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Cohort profile : the diet and healthy aging (DaHA) study in Singapore by Yu, Rongjun, Sun, Ye, Ye, Kaisy Xinhong, Feng, Qiushi, Lim, Su Lin, Mahendran, Rathi, Cheah, Irwin Kee-Mun, Foo, Roger Sik Yin, Chua, Ru Yuan, Gwee, Xinyi, Loh, Marie, Sarmugam, Rani, Khine, Wei Wei Thwe, Chao, Yin Xia, Larbi, Anis, Lee, Yuan Kun, Kumar, Alan Prem, Kennedy, Brian K., Kua, Ee-Heok, Feng, Lei

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Blood-based epigenome-wide analyses of chronic low-grade inflammation across diverse population cohorts by Hillary, Robert F., Ng, Hong Kiat, McCartney, Daniel L., Elliott, Hannah R., Walker, Rosie M., Campbell, Archie, Huang, Felicia, Direk, Kenan, Welsh, Paul, Sattar, Naveed, Corley, Janie, Hayward, Caroline, McIntosh, Andrew M., Sudlow, Cathie, Evans, Kathryn L., Cox, Simon R., Chambers, John Campbell, Loh, Marie, Relton, Caroline L., Marioni, Riccardo E., Yousefi, Paul D., Suderman, Matthew

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Effects of choral singing versus health education on cognitive decline and aging : a randomized controlled trial by Feng, Lei, Romero-Garcia, Rafael, Suckling, John, Tan, Jasmine, Larbi, Anis, Cheah, Irwin, Wong, Glenn, Tsakok, Maurine, Lanskey, Bernard, Lim, Darius, Li, Jialiang, Yang, Joanna, Goh, Benjamin, Teck, Tristan Gwee Chen, Ho, Allan, Wang, Xiu, Yu, Jin-Tai, Zhang, Can, Tan, Crystal, Chua, Michelle, Li, Junhua, Totman, John J., Wong, Caroline, Loh, Marie, Foo, Roger, Tan, Chay Hoon, Goh, Lee Gan, Mahendran, Rathi, Kennedy, Brian K., Kua, Ee-Heok

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DNA methylation and lipid metabolism : an EWAS of 226 metabolic measures by Gomez-Alonso, Monica del C., Kretschmer, Anja, Wilson, Rory, Pfeiffer, Liliane, Karhunen, Ville, Seppälä, Ilkka, Zhang, Weihua, Mittelstraß, Kirstin, Wahl, Simone, Matias-Garcia, Pamela R., Prokisch, Holger, Horn, Sacha, Meitinger, Thomas, Serrano-Garcia, Luis R., Sebert, Sylvain, Raitakari, Olli, Loh, Marie, Rathmann, Wolfgang, Müller-Nurasyid, Martina, Herder, Christian, Roden, Michael, Hurme, Mikko, Jarvelin, Marjo-Riitta, Ala-Korpela, Mika, Kooner, Jaspal S., Peters, Annette, Lehtimäki, Terho, Chambers, John Campbell, Gieger, Christian, Kettunen, Johannes, Waldenberger, Melanie

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The iHealth-T2D study, prevention of type 2 diabetes amongst South Asians with central obesity and prediabetes: study protocol for a randomised controlled trial by Kasturiratne, Anuradhani, Khawaja, Khadija I., Ahmad, Sajjad, Siddiqui, Samreen, Shahzad, Khurram, Athauda, Lathika K., Jayawardena, Ranil, Mahmood, Sara, Muilwijk, Mirthe, Batool, Tayyaba, Burney, Saira, Glover, Matthew, Palaniswamy, Saranya, Bamunuarachchi, Vodathi, Panda, Manju, Madawanarachchi, Suren, Rai, Baldeesh, Sattar, Iqra, Silva, Wnurinham, Waghdhare, Swati, Jarvelin, Marjo-Riitta, Rannan-Eliya, Ravindra P., Gage, Heather M., van Valkengoed, Irene G. M., Valabhji, Jonathan, Frost, Gary S., Loh, Marie, Wickremasinghe, Ananda R., Kooner, Jaspal S., Katulanda, Prasad, Jha, Sujeet, Chambers, John C.

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Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults by Chambers, John Campbell, Parmar, Priyanka, Lowry, Estelle, Cugliari, Giovanni, Suderman, Matthew, Wilson, Rory, Karhunen, Ville, Andrew, Toby, Wiklund, Petri, Wielscher, Matthias, Guarrera, Simonetta, Teumer, Alexander, Lehne, Benjamin, Milani, Lili, de Klein, Niek, Mishra, Pashupati P., Melton, Phillip E., Mandaviya, Pooja R., Kasela, Silva, Nano, Jana, Zhang, Weihua, Zhang, Yan, Mori, Trevor A., Bonnefond, Amelie, Uitterlinden, Andre G., Peters, Annette, Schöttker, Ben, Gieger, Christian, Anderson, Denise, Boomsma, Dorret I., Grabe, Hans J., Panico, Salvatore, Veldink, Jan H., van Meurs, Joyce B.J., van den Berg, Leonard, Heijmans, Bastiaan T., Muka, Taulant, Kooner, Jaspal S., Fischer, Krista, Waldenberger, Melanie, Beilin, Lawrence J., Franke, Lude, Loh, Marie, van Greevenbroek, Marleen M.J., Nauck, Matthias, Kähönen, Mika, Hurme, Mikko A., Raitakari, Olli T., Franco, Oscar H., Slagboom, P.Eline, van der Harst, Pim, Kunze, Sonja, Felix, Stephan B., Zhang, Tao, Chen, Wei, Froguel, Philippe, Huang, Rae-Chi, Lehtimäki, Terho, Rathmann, Wolfgang, Relton, Caroline L., Matullo, Giuseppe, Brenner, Hermann, Verweij, Niek, Li, Shengxu, Järvelin, Marjo-Riitta, Sebert, Sylvain

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