The 2-oxoglutarate-dependent oxygenase JMJD6 catalyses oxidation of lysine residues to give 5S-hydroxylysine residues. nork Mantri, M, Loik, N, Hamed, R, Claridge, T, McCullagh, J, Schofield, C

Investigating the contribution of the active site environment to the slow reaction of hypoxia-inducible factor prolyl hydroxylase domain 2 with oxygen. nork Tarhonskaya, H, Chowdhury, R, Leung, I, Loik, N, McCullagh, J, Claridge, T, Schofield, C, Flashman, E

Comparison of the substrate selectivity and biochemical properties of human and bacterial γ-butyrobetaine hydroxylase. nork Rydzik, A, Leung, I, Kochan, G, Loik, N, Henry, L, McDonough, M, Claridge, T, Schofield, C

Non-enzymatic chemistry enables 2-hydroxyglutarate-mediated activation of 2-oxoglutarate oxygenases. nork Tarhonskaya, H, Rydzik, A, Leung, I, Loik, N, Chan, M, Kawamura, A, McCullagh, J, Claridge, T, Flashman, E, Schofield, C

Substrate selectivity analyses of factor inhibiting hypoxia-inducible factor. nork Yang, M, Hardy, A, Chowdhury, R, Loik, N, Scotti, J, McCullagh, J, Claridge, T, McDonough, M, Ge, W, Schofield, C

Self-hydroxylation of the splicing factor lysyl hydroxylase, JMJD6 nork Mantri, M, Webby, C, Loik, N, Hamed, R, Nielsen, M, McDonough, M, McCullagh, J, Boettger, A, Schofield, C, Wolf, A

Non-competitive cyclic peptides for targeting enzyme-substrate complexes nork Mcallister, T, Yeh, T, Abboud, M, Leung, I, Hookway, E, King, O, Bhushan, B, Williams, S, Hopkinson, R, Muenzel, M, Loik, N, Chowdhury, R, Oppermann, U, Claridge, T, Goto, Y, Suga, H, Schofield, C, Kawamura, A

Human oxygen sensing may have origins in prokaryotic elongation factor Tu prolyl-hydroxylation. nork Scotti, J, Leung, I, Ge, W, Bentley, M, Paps, J, Kramer, H, Lee, J, Aik, W, Choi, H, Paulsen, S, Bowman, L, Loik, N, Horita, S, Ho, C, Kershaw, N, Tang, C, Claridge, T, Preston, G, McDonough, M, Schofield, C

Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans nork Ge, W, Wolf, A, Feng, T, Ho, C, Sekirnik, R, Zayer, A, Granatino, N, Cockman, M, Loenarz, C, Loik, N, Hardy, A, Claridge, T, Hamed, R, Chowdhury, R, Gong, L, Robinson, C, Trudgian, D, Jiang, M, Mackeen, M, Mccullagh, J, Gordiyenko, Y, Thalhammer, A, Yamamoto, A, Yang, M, Liu-Yi, P

Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans. nork Ge, W, Wolf, A, Feng, T, Ho, C, Sekirnik, R, Zayer, A, Granatino, N, Cockman, M, Loenarz, C, Loik, N, Hardy, A, Claridge, T, Hamed, R, Chowdhury, R, Gong, L, Robinson, C, Trudgian, D, Jiang, M, Mackeen, M, McCullagh, J, Gordiyenko, Y, Thalhammer, A, Yamamoto, A, Yang, M, Liu-Yi, P