CHK1 inhibition as a strategy for targeting fanconi anemia (FA) DNA repair pathway deficient tumors by Look A Thomas, Sidi Samuel, Kennedy Richard D, Chen Clark C, D'Andrea Alan

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TRIB2 reinforces the oncogenic transcriptional program controlled by the TAL1 complex in T-cell acute lymphoblastic leukemia by Tan, S H, Yam, A W Y, Lawton, L N, Wong, R W J, Young, R A, Look, A T, Sanda, T, Young, Richard A.

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Retinoic acid rewires the adrenergic core regulatory circuitry of childhood neuroblastoma by Zimmerman, Mark W, Durbin, Adam D, He, Shuning, Oppel, Felix, Shi, Hui, Tao, Ting, Li, Zhaodong, Berezovskaya, Alla, Liu, Yu, Zhang, Jinghui, Young, Richard A, Abraham, Brian J, Look, A Thomas

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APOBEC signature mutation generates an oncogenic enhancer that drives LMO1 expression in T-ALL by Li, Z, Abraham, B J, Berezovskaya, A, Farah, N, Liu, Y, Leon, T, Fielding, A, Tan, S H, Sanda, T, Weintraub, A S, Li, B, Shen, S, Zhang, J, Mansour, M R, Look, A T, Young, Richard A.

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An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element by Mansour, M. R., Abraham, B. J., Anders, L., Berezovskaya, A., Gutierrez, A., Durbin, A. D., Etchin, J., Lawton, L., Sallan, S. E., Silverman, L. B., Loh, M. L., Hunger, S. P., Sanda, T., Look, A. T., Young, Richard A.

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The TAL1 complex targets the FBXW7 tumor suppressor by activating miR-223 in human T cell acute lymphoblastic leukemia by Mansour, Marc R., Sanda, Takaomi, Lawton, Lee N., Li, Xiaoyu, Kreslavsky, Taras, Novina, Carl D., Brand, Marjorie, Gutierrez, Alejandro, Kelliher, Michelle A., Jamieson, Catriona H. M., von Boehmer, Harald, Young, Richard A., Look, A. Thomas

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Core Transcriptional Regulatory Circuit Controlled by the TAL1 Complex in Human T Cell Acute Lymphoblastic Leukemia by Sanda, Takaomi, Lawton, Lee N., Barrasa, M. Inmaculada, Fan, Zi Peng, Kohlhammer, Holger, Gutierrez, Alejandro, Ma, Wenxue, Tatarek, Jessica, Ahn, Yebin, Kelliher, Michelle A., Jamieson, Catriona H. M., Staudt, Louis M., Young, Richard A., Look, A. Thomas

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LIN28B regulates transcription and potentiates MYCN-induced neuroblastoma through binding to ZNF143 at target gene promotors by Tao, Ting, Shi, Hui, Mariani, Luca, Abraham, Brian J, Durbin, Adam D, Zimmerman, Mark W, Powers, John T, Missios, Pavlos, Ross, Kenneth N, Perez-Atayde, Antonio R, Bulyk, Martha L, Young, Richard A, Daley, George Q, Look, A Thomas

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LIN28B regulates transcription and potentiates MYCN-induced neuroblastoma through binding to ZNF143 at target gene promotors by Tao, Ting, Shi, Hui, Mariani, Luca, Abraham, Brian J., Durbin, Adam D., Zimmerman, Mark W., Powers, John T., Missios, Pavlos, Ross, Kenneth N., Perez-Atayde, Antonio R., Bulyk, Martha L., Young, Richard A., Daley, George Q., Look, A. Thomas

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Small genomic insertions form enhancers that misregulate oncogenes by Hnisz, Denes, Li, Zhaodong, Weichert-Leahey, Nina, Rahman, Sunniyat, Liu, Yu, Etchin, Julia, Li, Benshang, Shen, Shuhong, Zhang, Jinghui, Look, A. Thomas, Mansour, Marc R., Abraham, Brian Joseph, Weintraub, Abraham Selby, Kwiatkowski, Nick, Li, Charles Han, Lee, Tong Ihn, Young, Richard A.

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Aberrant AKT activation drives well-differentiated liposarcoma by Gutierrez, Alejandro, Snyder, Eric, Marino-Enriquez, Adrian, Zhang, Yi-Xiang, Sioletic, Stefano, Kozakewich, Elena, Grebliunaite, Ruta, Ou, Wen-bin, Sicinska, Ewa, Raut, Chandrajit P., Demetri, George D., Perez-Atayde, Antonio R., Wagner, Andrew J., Fletcher, Jonathan A., Fletcher, Christopher D. M., Look, A. Thomas

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Activation of the LMO2 oncogene through a somatically acquired neomorphic promoter in T-cell acute lymphoblastic leukemia by Rahman, Sunniyat, Magnussen, Michael, León, Theresa E., Farah, Nadine, Li, Zhaodong, Alapi, Krisztina Z., Mitchell, Rachel J., Naughton, Tom, Fielding, Adele K., Pizzey, Arnold, Bustraan, Sophia, Popa, Teodora, Pike-Overzet, Karin, Garcia-Perez, Laura, Gale, Rosemary E., Linch, David C., Staal, Frank J. T., Look, A. Thomas, Mansour, Marc R., Abraham, Brian Joseph, Allen, Christopher D, Young, Richard A.

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Targeting transcription regulation in cancer with a covalent CDK7 inhibitor by Kwiatkowski, Nicholas P., Zhang, Tinghu, Rahl, Peter B., Abraham, Brian J., Reddy, Jessica, Ficarro, Scott B., Dastur, Anahita, Amzallag, Arnaud, Ramaswamy, Sridhar, Tesar, Bethany, Jenkins, Catherine E., Hannett, Nancy M., McMillin, Douglas, Sanda, Takaomi, Sim, Taebo, Kim, Nam Doo, Look, A. Thomas, Mitsiades, Constantine S., Weng, Andrew P., Brown, Jennifer R., Benes, Cyril H., Marto, Jarrod A., Young, Richard A., Gray, Nathanael S.

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JDP2: An oncogenic bZIP transcription factor in T cell acute lymphoblastic leukemia by Mansour, Marc R., He, Shuning, Li, Zhaodong, Lobbardi, Riadh, Abraham, Brian J., Hug, Clemens, Rahman, Sunniyat, Leon, Theresa E., Kuang, You-Yi, Zimmerman, Mark W., Blonquist, Traci, Gjini, Evisa, Gutierrez, Alejandro, Tang, Qin, Garcia-Perez, Laura, Pike-Overzet, Karin, Anders, Lars, Berezovskaya, Alla, Zhou, Yi, Zon, Leonard I., Neuberg, Donna, Fielding, Adele K., Staal, Frank J.T., Langenau, David M., Sanda, Takaomi, Look, A. Thomas, Young, Richard A.

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Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism by Oldridge, Derek A., Wood, Andrew C., Weichert-Leahey, Nina, Crimmins, Ian, Sussman, Robyn, Winter, Cynthia, McDaniel, Lee D., Diamond, Maura, Hart, Lori S., Zhu, Shizhen, Durbin, Adam D., Anders, Lars, Tian, Lifeng, Zhang, Shile, Wei, Jun S., Khan, Javed, Bramlett, Kelli, Rahman, Nazneen, Capasso, Mario, Iolascon, Achille, Gerhard, Daniela S., Guidry Auvil, Jaime M., Hakonarson, Hakon, Diskin, Sharon J., Thomas Look, A., Maris, John M., Abraham, Brian Joseph, Young, Richard A.

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Cross-Cohort Analysis Identifies a TEAD4–MYCN Positive Feedback Loop as the Core Regulatory Element of High-Risk Neuroblastoma by Rajbhandari, Presha, Lopez, Gonzalo, Capdevila, Claudia, Salvatori, Beatrice, Yu, Jiyang, Rodriguez-Barrueco, Ruth, Martinez, Daniel, Yarmarkovich, Mark, Weichert-Leahey, Nina, Alvarez, Mariano J., Iyer, Archana, Harenza, Jo Lynne, Oldridge, Derek, De Preter, Katleen, Koster, Jan, Asgharzadeh, Shahab, Seeger, Robert C., Wei, Jun S., Khan, Javed, Vandesompele, Jo, Mestdagh, Pieter, Versteeg, Rogier, Look, A. Thomas, Iavarone, Antonio, Lasorella, Anna, Silva, Jose M., Maris, John M., Califano, Andrea, Abraham, Brian Joseph, Young, Richard A.

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