Insights into IGH clonal evolution in BCP-ALL: frequency, mechanisms, associations, and diagnostic implications by Franziska Darzentas, Monika Szczepanowski, Michaela Kotrová, Alina Hartmann, Alina Hartmann, Alina Hartmann, Thomas Beder, Thomas Beder, Nicola Gökbuget, Stefan Schwartz, Stefan Schwartz, Lorenz Bastian, Lorenz Bastian, Lorenz Bastian, Claudia Dorothea Baldus, Claudia Dorothea Baldus, Claudia Dorothea Baldus, Karol Pál, Nikos Darzentas, Monika Brüggemann, Monika Brüggemann, Monika Brüggemann

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IGH Rearrangement Evolution in Adult KMT2A-rearranged B-cell Precursor ALL: Implications for Cell-of-origin and MRD Monitoring by Franziska Darzentas, Monika Szczepanowski, Michaela Kotrová, Miriam Kelm, Alina Hartmann, Thomas Beder, Nicola Gökbuget, Martin Neumann, Lorenz Bastian, Claudia D. Baldus, Karol Pál, Nikos Darzentas, Monika Brüggemann

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Myeloid checkpoint blockade improves killing of T-acute lymphoblastic leukemia cells by an IgA2 variant of daratumumab by Niklas Baumann, Christian Arndt, Judith Petersen, Marta Lustig, Thies Rösner, Katja Klausz, Christian Kellner, Miriam Bultmann, Lorenz Bastian, Fotini Vogiatzi, Jeanette H. W. Leusen, Renate Burger, Denis M. Schewe, Matthias Peipp, Thomas Valerius

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AP-1 Transcription Factor Complex Members FOSB and FOS are Linked With CNS Infiltration and Inferior Prognosis in Childhood T-ALL by Lea Spory, Johannes Zimmermann, Michaela Vossen-Gajcy, Thomas Beder, Lorenz Bastian, Ameera Alsadeq, Dorothee Winterberg, Fotini Vogiatzi, Tim Wirbelauer, Hilal Bhat, Arndt Borkhardt, Sanil Bhatia, Martin Schrappe, Gunnar Cario, Denis M. Schewe, Lennart Lenk

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Chemotherapy‐induced release of ADAM17 bearing EV as a potential resistance mechanism in ovarian cancer by Gerrit Hugendieck, Marcus Lettau, Svenja Andreas, Sabrina Neumann, Natalie Reinhardt, Philipp Arnold, Franziska Theilig, Lorenz Bastian, Christoph Rogmans, Jörg P. Weimer, Inken Flörkemeier, Daniela Wesch, Norbert Arnold, Nicolai Maass, Ottmar Janssen, Dirk Bauerschlag, Nina Hedemann

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An alternative CYB5A transcript is expressed in aneuploid ALL and enriched in relapse by Lorenz Bartsch, Michael P. Schroeder, Sonja Hänzelmann, Lorenz Bastian, Juan Lázaro-Navarro, Cornelia Schlee, Jutta Ortiz Tanchez, Veronika Schulze, Konstandina Isaakidis, Michael A. Rieger, Nicola Gökbuget, Cornelia Eckert, Hubert Serve, Martin Horstmann, Martin Schrappe, Monika Brüggemann, Claudia D. Baldus, Martin Neumann

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FAT1 expression in T-cell acute lymphoblastic leukemia (T-ALL) modulates proliferation and WNT signaling by Sven Liebig, Martin Neumann, Patricia Silva, Jutta Ortiz-Tanchez, Veronika Schulze, Konstandina Isaakidis, Cornelia Schlee, Michael P. Schroeder, Thomas Beder, Luc G. T. Morris, Timothy A. Chan, Lorenz Bastian, Thomas Burmeister, Stefan Schwartz, Nicola Gökbuget, Liliana H. Mochmann, Claudia D. Baldus

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Disruption of the sialic acid/Siglec-9 axis improves antibody-mediated neutrophil cytotoxicity towards tumor cells by Marta Lustig, Chilam Chan, J. H. Marco Jansen, Maria Bräutigam, Max A. Kölling, Carina Lynn Gehlert, Niklas Baumann, Simone Mester, Simone Mester, Stian Foss, Stian Foss, Jan Terje Andersen, Jan Terje Andersen, Lorenz Bastian, Peter Sondermann, Matthias Peipp, Renate Burger, Jeanette H. W. Leusen, Thomas Valerius

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Long non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia by Alva Rani James, Michael P. Schroeder, Martin Neumann, Lorenz Bastian, Cornelia Eckert, Nicola Gökbuget, Jutta Ortiz Tanchez, Cornelia Schlee, Konstandina Isaakidis, Stefan Schwartz, Thomas Burmeister, Arend von Stackelberg, Michael A. Rieger, Stefanie Göllner, Martin Horstman, Martin Schrappe, Renate Kirschner-Schwabe, Monika Brüggemann, Carsten Müller-Tidow, Hubert Serve, Altuna Akalin, Claudia D. Baldus

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The Gene Expression Classifier ALLCatchR Identifies B-cell Precursor ALL Subtypes and Underlying Developmental Trajectories Across Age by Thomas Beder, Björn-Thore Hansen, Alina M. Hartmann, Johannes Zimmermann, Eric Amelunxen, Nadine Wolgast, Wencke Walter, Marketa Zaliova, Željko Antić, Philippe Chouvarine, Lorenz Bartsch, Malwine J. Barz, Miriam Bultmann, Johanna Horns, Sonja Bendig, Jan Kässens, Christoph Kaleta, Gunnar Cario, Martin Schrappe, Martin Neumann, Nicola Gökbuget, Anke Katharina Bergmann, Jan Trka, Claudia Haferlach, Monika Brüggemann, Claudia D. Baldus, Lorenz Bastian

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In vivo inducible reverse genetics in patients’ tumors to identify individual therapeutic targets by Michela Carlet, Kerstin Völse, Jenny Vergalli, Martin Becker, Tobias Herold, Anja Arner, Daniela Senft, Vindi Jurinovic, Wen-Hsin Liu, Yuqiao Gao, Veronika Dill, Boris Fehse, Claudia D. Baldus, Lorenz Bastian, Lennart Lenk, Denis M. Schewe, Johannes W. Bagnoli, Binje Vick, Jan Philipp Schmid, Alexander Wilhelm, Rolf Marschalek, Philipp J. Jost, Cornelius Miething, Kristoffer Riecken, Marc Schmidt-Supprian, Vera Binder, Irmela Jeremias

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