Louise Showe

Louise C. Showe is an American biomedical researcher who was scientific director of the Genomics Facility and the Bioinformatics Facility at The Wistar Institute in Philadelphia. Her research focused on functional genomics and how they can be used to better understand the immune system and cancer. She retired in 2024.

Showe has said that being able to "globally screen gene expression patterns using genomics and proteomics appears to have injected a new level of enthusiasm for learning what is going on in complex cancers that have been particularly recalcitrant to therapy." Recently, Showe's research led to the creation of a blood test that could be used to test for lung cancer using a 29-gene assay. The company OncoCyte has partnered with Wistar to develop lung cancer diagnostic tests. Provided by Wikipedia
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  1. 1
    GediNET for discovering gene associations across diseases using knowledge based machine learning approach

    GediNET for discovering gene associations across diseases using knowledge based machine learning approach by Emma Qumsiyeh, Louise Showe, Malik Yousef

    Published 2022-11-01
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  2. 2
    Lack of Atorvastatin Effect on Monocyte Gene Expression and Inflammatory Markers in HIV-1- infected ART-suppressed Individuals at Risk of non-AIDS Comorbidities

    Lack of Atorvastatin Effect on Monocyte Gene Expression and Inflammatory Markers in HIV-1- infected ART-suppressed Individuals at Risk of non-AIDS Comorbidities by Anjana Yadav, Andrew Kossenkov, Louise Showe, Sarah Ratcliffe, Grace Choi, Luis Montaner, Pablo Tebas, Pamela Shaw, Ronald Collman

    Published 2021-08-01
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  3. 3
    Constitutive gene expression in monocytes from chronic HIV-1 infection overlaps with acute Toll-like receptor induced monocyte activation profiles.

    Constitutive gene expression in monocytes from chronic HIV-1 infection overlaps with acute Toll-like receptor induced monocyte activation profiles. by Bethsebah Gekonge, Malavika S Giri, Andrew V Kossenkov, Michael Nebozyhn, Malik Yousef, Karam Mounzer, Louise Showe, Luis J Montaner

    Published 2012-01-01
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  4. 4
    A multi-omics approach to Epstein-Barr virus immortalization of B-cells reveals EBNA1 chromatin pioneering activities targeting nucleotide metabolism.

    A multi-omics approach to Epstein-Barr virus immortalization of B-cells reveals EBNA1 chromatin pioneering activities targeting nucleotide metabolism. by R Jason Lamontagne, Samantha S Soldan, Chenhe Su, Andreas Wiedmer, Kyoung Jae Won, Fang Lu, Aaron R Goldman, Jayamanna Wickramasinghe, Hsin-Yao Tang, David W Speicher, Louise Showe, Andrew V Kossenkov, Paul M Lieberman

    Published 2021-01-01
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