Structure and assembly properties of the N-terminal domain of the prion Ure2p in isolation and in its natural context. Autor Luc Bousset, Jonathan Bonnefoy, Yannick Sourigues, Frank Wien, Ronald Melki

Získat plný text

The prion-like domain of Drosophila Imp promotes axonal transport of RNP granules in vivo Autor Jeshlee Vijayakumar, Charlène Perrois, Marjorie Heim, Luc Bousset, Simon Alberti, Florence Besse

Získat plný text

Unlike twins: an NMR comparison of two α-synuclein polymorphs featuring different toxicity. Autor Julia Gath, Luc Bousset, Birgit Habenstein, Ronald Melki, Anja Böckmann, Beat H Meier

Získat plný text

Peripheral Inflammation Regulates CNS Immune Surveillance Through the Recruitment of Inflammatory Monocytes Upon Systemic α-Synuclein Administration Autor Javier María Peralta Ramos, Pablo Iribarren, Luc Bousset, Ronald Melki, Veerle Baekelandt, Anke Van der Perren

Získat plný text

Detection of alpha-synuclein aggregates in gastrointestinal biopsies by protein misfolding cyclic amplification Autor Alexis Fenyi, Laurène Leclair-Visonneau, Thomas Clairembault, Emmanuel Coron, Michel Neunlist, Ronald Melki, Pascal Derkinderen, Luc Bousset

Získat plný text

Prion Amyloid Polymorphs – The Tag Might Change It All Autor Luc Bousset, Nina Luckgei, Mehdi Kabani, Carole Gardiennet, Anne K. Schütz, Ronald Melki, Beat H. Meier, Anja Böckmann

Získat plný text

Propagation of α-Synuclein Strains within Human Reconstructed Neuronal Network Autor Simona Gribaudo, Philippe Tixador, Luc Bousset, Alexis Fenyi, Patricia Lino, Ronald Melki, Jean-Michel Peyrin, Anselme L. Perrier

Získat plný text

Seeding Propensity and Characteristics of Pathogenic αSyn Assemblies in Formalin-Fixed Human Tissue from the Enteric Nervous System, Olfactory Bulb, and Brainstem in Cases Staged f... Autor Alexis Fenyi, Charles Duyckaerts, Luc Bousset, Heiko Braak, Kelly Del Tredici, Ronald Melki, on behalf of the Brainbank Neuro-CEB Neuropathology Network

Získat plný text

α-Synuclein conformational strains spread, seed and target neuronal cells differentially after injection into the olfactory bulb Autor Nolwen L. Rey, Luc Bousset, Sonia George, Zachary Madaj, Lindsay Meyerdirk, Emily Schulz, Jennifer A. Steiner, Ronald Melki, Patrik Brundin

Získat plný text

Dopamine D2 Long Receptors Are Critical for Caveolae-Mediated α-Synuclein Uptake in Cultured Dopaminergic Neurons Autor Ichiro Kawahata, Tomoki Sekimori, Haoyang Wang, Yanyan Wang, Toshikuni Sasaoka, Luc Bousset, Ronald Melki, Tomohiro Mizobata, Yasushi Kawata, Kohji Fukunaga

Získat plný text

Long term worsening of amyloid pathology, cerebral function, and cognition after a single inoculation of beta-amyloid seeds with Osaka mutation Autor Marina Célestine, Muriel Jacquier-Sarlin, Eve Borel, Fanny Petit, Jean-Baptiste Perot, Anne-Sophie Hérard, Luc Bousset, Alain Buisson, Marc Dhenain

Získat plný text

Phenotypic manifestation of α-synuclein strains derived from Parkinson’s disease and multiple system atrophy in human dopaminergic neurons Autor Benedict Tanudjojo, Samiha S. Shaikh, Alexis Fenyi, Luc Bousset, Devika Agarwal, Jade Marsh, Christos Zois, Sabrina Heman-Ackah, Roman Fischer, David Sims, Ronald Melki, George K. Tofaris

Získat plný text

Data in support of the identification of neuronal and astrocyte proteins interacting with extracellularly applied oligomeric and fibrillar α-synuclein assemblies by mass spectromet... Autor Amulya Nidhi Shrivastava, Virginie Redeker, Nicolas Fritz, Laura Pieri, Leandro G. Almeida, Maria Spolidoro, Thomas Liebmann, Luc Bousset, Marianne Renner, Clément Léna, Anita Aperia, Ronald Melki, Antoine Triller

Získat plný text

Intranasal administration of α-synuclein preformed fibrils triggers microglial iron deposition in the substantia nigra of Macaca fascicularis Autor Jian-Jun Guo, Feng Yue, Dong-Yan Song, Luc Bousset, Xin Liang, Jing Tang, Lin Yuan, Wen Li, Ronald Melki, Yong Tang, Piu Chan, Chuang Guo, Jia-Yi Li

Získat plný text

Functional and neuropathological changes induced by injection of distinct alpha-synuclein strains: A pilot study in non-human primates Autor Audrey Fayard, Alexis Fenyi, Sonia Lavisse, Sandra Dovero, Luc Bousset, Tracy Bellande, Sophie Lecourtois, Christophe Jouy, Martine Guillermier, Caroline Jan, Pauline Gipchtein, Benjamin Dehay, Erwan Bezard, Ronald Melki, Philippe Hantraye, Romina Aron Badin

Získat plný text

TNF-α and α-synuclein fibrils differently regulate human astrocyte immune reactivity and impair mitochondrial respiration Autor Kaspar Russ, Gabriel Teku, Luc Bousset, Virginie Redeker, Sara Piel, Ekaterina Savchenko, Yuriy Pomeshchik, Jimmy Savistchenko, Tina C. Stummann, Carla Azevedo, Anna Collin, Stefano Goldwurm, Karina Fog, Eskil Elmer, Mauno Vihinen, Ronald Melki, Laurent Roybon

Získat plný text

Neurons with Cat’s Eyes: A Synthetic Strain of α-Synuclein Fibrils Seeding Neuronal Intranuclear Inclusions Autor Francesca De Giorgi, Muhammed Bilal Abdul-Shukkoor, Marianna Kashyrina, Leslie-Ann Largitte, Francesco De Nuccio, Brice Kauffmann, Alons Lends, Florent Laferrière, Sébastien Bonhommeau, Dario Domenico Lofrumento, Luc Bousset, Erwan Bezard, Thierry Buffeteau, Antoine Loquet, François Ichas

Získat plný text

Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy Autor Ricardo Guerrero-Ferreira, Nicholas MI Taylor, Ana-Andreea Arteni, Pratibha Kumari, Daniel Mona, Philippe Ringler, Markus Britschgi, Matthias E Lauer, Ali Makky, Joeri Verasdonck, Roland Riek, Ronald Melki, Beat H Meier, Anja Böckmann, Luc Bousset, Henning Stahlberg

Získat plný text