Characterizing Features of Human Circulating B Cells Carrying CLL-Like Stereotyped Immunoglobulin Rearrangements by Davide Bagnara, Monica Colombo, Daniele Reverberi, Serena Matis, Rosanna Massara, Niccolò Cardente, Gianluca Ubezio, Vanessa Agostini, Luca Agnelli, Luca Agnelli, Antonino Neri, Martina Cardillo, Stefano Vergani, Fabio Ghiotto, Fabio Ghiotto, Andrea Nicola Mazzarello, Fortunato Morabito, Fortunato Morabito, Giovanna Cutrona, Manlio Ferrarini, Franco Fais, Franco Fais

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Management of BRCA Tumour Testing in an Integrated Molecular Tumour Board Multidisciplinary Model by Jacopo Azzollini, Andrea Vingiani, Andrea Vingiani, Luca Agnelli, Luca Agnelli, Elena Tamborini, Federica Perrone, Elena Conca, Iolanda Capone, Adele Busico, Bernard Peissel, Erica Rosina, Monika Ducceschi, Mara Mantiero, Salvatore Lopez, Francesco Raspagliesi, Monica Niger, Matteo Duca, Silvia Damian, Claudia Proto, Filippo de Braud, Filippo de Braud, Giancarlo Pruneri, Giancarlo Pruneri, Siranoush Manoukian

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Prevalence of BRCA homopolymeric indels in an ION Torrent-based tumour-to-germline testing workflow in high-grade ovarian carcinoma by Jacopo Azzollini, Luca Agnelli, Elena Conca, Tommaso Torelli, Adele Busico, Iolanda Capone, Marta Angelini, Elena Tamborini, Federica Perrone, Andrea Vingiani, Daniele Lorenzini, Bernard Peissel, Giancarlo Pruneri, Siranoush Manoukian

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Expression Pattern and Biological Significance of the lncRNA ST3GAL6-AS1 in Multiple Myeloma by Domenica Ronchetti, Katia Todoerti, Cristina Vinci, Vanessa Favasuli, Luca Agnelli, Martina Manzoni, Francesca Pelizzoni, Raffaella Chiaramonte, Natalia Platonova, Nicola Giuliani, Pierfrancesco Tassone, Nicola Amodio, Antonino Neri, Elisa Taiana

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P830: IDENTIFICATION OF NOVEL TARGET GENES CORRELATED WITH 1Q21 AMPLIFICATION IN PATIENTS WITH SMOLDERING MYELOMA AND MULTIPLE MYELOMA by Nicolas Thomas Iannozzi, Jessica Burroughs Garcia, Paola Storti, Denise Toscani, Valentina Marchica, Valentina Franceschi, Luca Agnelli, Vincenzo Raimondi, Giannalisa Todaro, Oxana Lungu, Matia Bernardi, Gabriella Sammarelli, Gaetano Donofrio, Benedetta Dalla Palma, Nicola Giuliani

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ESR1 gene amplification and MAP3K mutations are selected during adjuvant endocrine therapies in relapsing Hormone Receptor-positive, HER2-negative breast cancer (HR+ HER2- BC). by Lorenzo Ferrando, Andrea Vingiani, Anna Garuti, Claudio Vernieri, Antonino Belfiore, Luca Agnelli, Gianpaolo Dagrada, Diana Ivanoiu, Giuseppina Bonizzi, Elisabetta Munzone, Luana Lippolis, Martina Dameri, Francesco Ravera, Marco Colleoni, Giuseppe Viale, Luca Magnani, Alberto Ballestrero, Gabriele Zoppoli, Giancarlo Pruneri

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Tracing CLL-biased stereotyped immunoglobulin gene rearrangements in normal B cell subsets using a high-throughput immunogenetic approach by Monica Colombo, Davide Bagnara, Daniele Reverberi, Serena Matis, Martina Cardillo, Rosanna Massara, Luca Mastracci, Jean Louis Ravetti, Luca Agnelli, Antonino Neri, Michela Mazzocco, Margherita Squillario, Andrea Nicola Mazzarello, Giovanna Cutrona, Andreas Agathangelidis, Kostas Stamatopoulos, Manlio Ferrarini, Franco Fais

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A2AR Expression and Immunosuppressive Environment Independent of <i>KRAS</i> and <i>GNAS</i> Mutations in Pseudomyxoma Peritonei by Shigeki Kusamura, Adele Busico, Elena Conca, Iolanda Capone, Luca Agnelli, Daniele Lorenzini, Silvia Brich, Marta Angelini, Chiara Costanza Volpi, Desirè Viola Trupia, Vincenzo Lagano, Tommaso Torelli, Annunziata Gloghini, Dario Baratti, Marcello Guaglio, Massimo Milione, Marcello Deraco, Federica Perrone

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Evidence of distinct tumour-propagating cell populations with different properties in primary human hepatocellular carcinoma. by Federico Colombo, Francesca Baldan, Silvia Mazzucchelli, Ines Martin-Padura, Paola Marighetti, Alessandra Cattaneo, Barbara Foglieni, Marta Spreafico, Silvana Guerneri, Marco Baccarin, Francesco Bertolini, Giorgio Rossi, Vincenzo Mazzaferro, Massimiliano Cadamuro, Marco Maggioni, Luca Agnelli, Paolo Rebulla, Daniele Prati, Laura Porretti

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Targeted RNA-sequencing analysis for fusion transcripts detection in tumor diagnostics: assessment of bioinformatic tools reliability in FFPE samples by Iolanda Capone, Fabio Bozzi, Gian Paolo Dagrada, Paolo Verderio, Elena Conca, Adele Busico, Maria Adele Testi, Valentina Monti, Matteo Duca, Claudia Proto, Silvia Damian, Alberta Piccolo, Federica Perrone, Elena Tamborini, Andrea Devecchi, Paola Collini, Daniele Lorenzini, Andrea Vingiani, Luca Agnelli, Giancarlo Pruneri

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Relevance of stereotyped B-cell receptors in the context of the molecular, cytogenetic and clinical features of chronic lymphocytic leukemia. by Francesco Maura, Giovanna Cutrona, Sonia Fabris, Monica Colombo, Giacomo Tuana, Luca Agnelli, Serena Matis, Marta Lionetti, Massimo Gentile, Anna Grazia Recchia, Francesco Di Raimondo, Caterina Musolino, Fiorella Ilariucci, Nicola Di Renzo, Emanuela Pesce, Stefano Molica, Massimo Federico, Agostino Cortelezzi, Fortunato Morabito, Manlio Ferrarini, Antonino Neri

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Insulin growth factor 1 receptor expression is associated with NOTCH1 mutation, trisomy 12 and aggressive clinical course in chronic lymphocytic leukaemia. by Francesco Maura, Laura Mosca, Sonia Fabris, Giovanna Cutrona, Serena Matis, Marta Lionetti, Luca Agnelli, Marzia Barbieri, Marianna D'Anca, Martina Manzoni, Monica Colombo, Carlotta Massucco, Daniele Reverberi, Massimo Gentile, Anna Grazia Recchia, Sabrina Bossio, Fiorella Ilariucci, Caterina Musolino, Francesco Di Raimondo, Agostino Cortelezzi, Fortunato Morabito, Manlio Ferrarini, Antonino Neri

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Myeloma Cells Deplete Bone Marrow Glutamine and Inhibit Osteoblast Differentiation Limiting Asparagine Availability by Martina Chiu, Denise Toscani, Valentina Marchica, Giuseppe Taurino, Federica Costa, Massimiliano G. Bianchi, Roberta Andreoli, Valentina Franceschi, Paola Storti, Jessica Burroughs-Garcia, Rosa Alba Eufemiese, Benedetta Dalla Palma, Nicoletta Campanini, Eugenia Martella, Cristina Mancini, Jixiu Shan, Michael S. Kilberg, Giovanna D’Amico, Erica Dander, Luca Agnelli, Giancarlo Pruneri, Gaetano Donofrio, Ovidio Bussolati, Nicola Giuliani

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MGMT inactivation as a new biomarker in patients with advanced biliary tract cancers by Monica Niger, Federico Nichetti, Andrea Casadei‐Gardini, Federica Morano, Chiara Pircher, Elena Tamborini, Federica Perrone, Matteo Canale, Daniel B. Lipka, Andrea Vingiani, Luca Agnelli, Anna Dobberkau, Jennifer Hüllein, Felix Korell, Christoph E. Heilig, Sara Pusceddu, Francesca Corti, Michele Droz, Paola Ulivi, Michele Prisciandaro, Maria Antista, Marta Bini, Laura Cattaneo, Massimo Milione, Hanno Glimm, Bruno C. Köhler, Giancarlo Pruneri, Daniel Hübschmann, Stefan Fröhling, Vincenzo Mazzaferro, Filippo Pietrantonio, Maria Di Bartolomeo, Filippo deBraud

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PEOPLE (NTC03447678), a phase II trial to test pembrolizumab as first-line treatment in patients with advanced NSCLC with PD-L1 by Filippo de Braud, Valter Torri, Giuseppe Lo Russo, Claudia Proto, Roberto Ferrara, Monica Ganzinelli, Marina Chiara Garassino, Giuseppe Viscardi, Giorgio Trinchieri, Mario Occhipinti, Rita Leporati, Marta Brambilla, Luca Agnelli, Silvia Brich, Francesco Sgambelluri, Roberta Mortarini, Andrea Anichini, Leonardo Provenzano, Daniele Lorenzini, Arsela Prelaj, James Dolezal, Teresa Beninato, Tiziana Triulzi, Alessandra Fabbri, Laura Mazzeo, Andrea Spagnoletti, Vanja Miskovic, Alessandra Laura Giulia Pedrocchi, Francesco Trovo', Sara Manglaviti, Claudia Giani, Paolo Ambrosini, Andrea Franza, John McCulloch, Tommaso Torelli, Giancarlo Pruneri

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