PATHOPHISIOLOGY OF SICKLE CELL DISEASE AND NEW DRUGS FOR THE TREATMENT by Lucia De Franceschi

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NEW THERAPEUTIC OPTIONS FOR THE TREATMENT OF SICKLE CELL DISEASE by Alessandro Matte, Filippo Mazzi, Enrica Federti, Oliviero Olivieri, Lucia De Franceschi

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Pharmacological Induction of Fetal Hemoglobin in β-Thalassemia and Sickle Cell Disease: An Updated Perspective by Rayan Bou-Fakhredin, Lucia De Franceschi, Irene Motta, Maria Domenica Cappellini, Ali T. Taher

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Redox Balance in β-Thalassemia and Sickle Cell Disease: A Love and Hate Relationship by Rayan Bou-Fakhredin, Lucia De Franceschi, Irene Motta, Assaad A. Eid, Ali T. Taher, Maria Domenica Cappellini

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Oxidation Impacts the Intracellular Signaling Machinery in Hematological Disorders by Elena Tibaldi, Enrica Federti, Alessandro Matte, Iana Iatcenko, Anand B. Wilson, Veronica Riccardi, Mario Angelo Pagano, Lucia De Franceschi

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NCOA4 Deficiency Impairs Systemic Iron Homeostasis by Roberto Bellelli, Giorgia Federico, Alessandro Matte’, David Colecchia, Achille Iolascon, Mario Chiariello, Massimo Santoro, Lucia De Franceschi, Francesca Carlomagno

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EHA Research Roadmap on Hemoglobinopathies and Thalassemia: An Update by Achille Iolascon, Lucia De Franceschi, Martina Muckenthaler, Ali Taher, David Rees, Mariane de Montalembert, Stefano Rivella, Androulla Eleftheriou, Maria Domenica Cappellini

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K-CL co-transport plays an important role in normal and β thalassemic erythropoiesis by Lucia De Franceschi, Luisa Ronzoni, Maria Domenica Cappellini, Flora Cimmino, Angela Siciliano, Seth L. Alper, Veronica Servedio, Christian Pozzobon, Achille Iolascon

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Low-dose anti-IL 5 treatment in idiopathic hypereosinophilic syndrome: towards a precision medicine approach for remission maintenance by Marco Caminati, Matteo Maule, Roberto Benoni, Claudio Micheletto, Cristina Tecchio, Rachele Vaia, Lucia De Franceschi, Gabriella Guarnieri, Andrea Vianello, Gianenrico Senna

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P1458: MITAPIVAT AMELIORATES IN VITRO HUMAN Β THALASSEMIC ERYTHROID MATURATION INDEX AND MODULATES THE EXPRESSION OF THE CYTOPROTECTOR PEROXIREDOXIN-2. by Alessandro Matte’, Richard Pozzetto Huot, Andrea Mattarei, Alberto Ongaro, Alice Passarini, Angela Siciliano, Roberta Russo, Achille Iolascon, Carlo Brugnara, Lucia De Franceschi

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P1449: SAFETY PROFILE OF KETOROLAC CONTINUOUS INFUSION IN SICKLE CELL RELATED ACUTE VASO-OCCLUSIVE CRISIS by Valeria Maria Pinto, Barbara Gianesin, Salvatore Sardo, Filippo Mazzi, Giammarco Baiardi, Sofia Menotti, Fabio Piras, Gabriele Finco, Gian Luca Forni, Lucia De Franceschi

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Abnormal modulation of cell protective systems in response to ischemic/reperfusion injury is important in the development of mouse sickle cell hepatopathy by Angela Siciliano, Giorgio Malpeli, Orah S. Platt, Christophe Lebouef, Anne Janin, Aldo Scarpa, Oliviero Olivieri, Eliana Amato, Roberto Corrocher, Yves Beuzard, Lucia De Franceschi

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Two-photon microscopy imaging of thy1GFP-M transgenic mice: a novel animal model to investigate brain dendritic cell subsets in vivo. by Claudia Laperchia, Anna L Allegra Mascaro, Leonardo Sacconi, Anna Andrioli, Alessandro Mattè, Lucia De Franceschi, Gigliola Grassi-Zucconi, Marina Bentivoglio, Mario Buffelli, Francesco S Pavone

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Oxidative stress modulates heme synthesis and induces peroxiredoxin-2 as a novel cytoprotective response in β-thalassemic erythropoiesis by Lucia De Franceschi, Mariarita Bertoldi, Luigia De Falco, Sara Santos Franco, Luisa Ronzoni, Franco Turrini, Alessandra Colancecco, Clara Camaschella, Maria Domenica Cappellini, Achille Iolascon

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Medicinal plants used by "Passo da Ilha" rural community in the city of Pato Branco, southern Brazil by José A. Marchese, Lin C. Ming, Lucia de Franceschi, Rubia C. Camochena, Greice D.R. Gomes, Marcos V. Paladini, Diogo Capelin, Cristine F. Marchese

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Adaptative Up-Regulation of PRX2 and PRX5 Expression Characterizes Brain from a Mouse Model of Chorea-Acanthocytosis by Enrica Federti, Alessandro Matte, Veronica Riccardi, Kevin Peikert, Seth L. Alper, Adrian Danek, Ruth H. Walker, Angela Siciliano, Iana Iatcenko, Andreas Hermann, Lucia De Franceschi

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PIEZO1-R1864H rare variant accounts for a genetic phenotype-modifier role in dehydrated hereditary stomatocytosis by Immacolata Andolfo, Francesco Manna, Gianluca De Rosa, Barbara Eleni Rosato, Antonella Gambale, Giovanna Tomaiuolo, Antonio Carciati, Roberta Marra, Lucia De Franceschi, Achille Iolascon, Roberta Russo

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Abnormal red cell structure and function in neuroacanthocytosis. by Judith C A Cluitmans, Carlo Tomelleri, Zuhal Yapici, Sip Dinkla, Petra Bovee-Geurts, Venkatachalam Chokkalingam, Lucia De Franceschi, Roland Brock, Giel J G C M Bosman

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A novel erythroid anion exchange variant (Gly796Arg) of hereditary stomatocytosis associated with dyserythropoiesis by Achille Iolascon, Luigia De Falco, Franck Borgese, Maria Rosaria Esposito, Rosa Anna Avvisati, Pietro Izzo, Carmelo Piscopo, Helene Guizouarn, Andrea Biondani, Antonella Pantaleo, Lucia De Franceschi

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Dietary ω-3 fatty acids protect against vasculopathy in a transgenic mouse model of sickle cell disease by Brian T. Kalish, Alessandro Matte, Immacolata Andolfo, Achille Iolascon, Olga Weinberg, Alessandra Ghigo, James Cimino, Angela Siciliano, Emilio Hirsch, Enrica Federti, Mark Puder, Carlo Brugnara, Lucia De Franceschi

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