Modeling Nonalcoholic Fatty Liver Disease in the Dish Using Human-Specific Platforms: Strategies and LimitationsSummary by Milad Rezvani, Ludovic Vallier, Adrien Guillot

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Monogenic Diabetes Modeling: In Vitro Pancreatic Differentiation From Human Pluripotent Stem Cells Gains Momentum by Juan Ignacio Burgos, Ludovic Vallier, Santiago A. Rodríguez-Seguí

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International Coordination of Large-Scale Human Induced Pluripotent Stem Cell Initiatives: Wellcome Trust and ISSCR Workshops White Paper by Filipa A.C. Soares, Michael Sheldon, Mahendra Rao, Christine Mummery, Ludovic Vallier

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GMP-grade neural progenitor derivation and differentiation from clinical-grade human embryonic stem cells by Loriana Vitillo, Catherine Durance, Zoe Hewitt, Harry Moore, Austin Smith, Ludovic Vallier

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Simultaneous depletion of RB, RBL1 and RBL2 affects endoderm differentiation of human embryonic stem cells by Shota Nakanoh, Juned Kadiwala, Laetitia Pinte, Carola Maria Morell, An-Sofie Lenaerts, Ludovic Vallier

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Simultaneous depletion of RB, RBL1 and RBL2 affects endoderm differentiation of human embryonic stem cells. by Shota Nakanoh, Juned Kadiwala, Laetitia Pinte, Carola Maria Morell, An-Sofie Lenaerts, Ludovic Vallier

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Genetic background drives transcriptional variation in human induced pluripotent stem cells. by Foad Rouhani, Natsuhiko Kumasaka, Miguel Cardoso de Brito, Allan Bradley, Ludovic Vallier, Daniel Gaffney

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Assessing motile cilia coverage and beat frequency in mammalian in vitro cell culture tissues by Ricardo Fradique, Erika Causa, Clara Delahousse, Jurij Kotar, Laetitia Pinte, Ludovic Vallier, Marta Vila-Gonzalez, Pietro Cicuta

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Analysis of endothelial-to-haematopoietic transition at the single cell level identifies cell cycle regulation as a driver of differentiation by Giovanni Canu, Emmanouil Athanasiadis, Rodrigo A. Grandy, Jose Garcia-Bernardo, Paulina M. Strzelecka, Ludovic Vallier, Daniel Ortmann, Ana Cvejic

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Multiple roles of Activin/Nodal, bone morphogenetic protein, fibroblast growth factor and Wnt/β-catenin signalling in the anterior neural patterning of adherent human embryonic ste... by Giuseppe Lupo, Claire Novorol, Joseph R. Smith, Ludovic Vallier, Elena Miranda, Morgan Alexander, Stefano Biagioni, Roger A. Pedersen, William A. Harris

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Mutational History of a Human Cell Lineage from Somatic to Induced Pluripotent Stem Cells. by Foad J Rouhani, Serena Nik-Zainal, Arthur Wuster, Yilong Li, Nathalie Conte, Hiroko Koike-Yusa, Natsuhiko Kumasaka, Ludovic Vallier, Kosuke Yusa, Allan Bradley

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Maturation of induced pluripotent stem cell derived hepatocytes by 3D-culture. by Richard L Gieseck, Nicholas R F Hannan, Roque Bort, Neil A Hanley, Rosemary A L Drake, Grant W W Cameron, Thomas A Wynn, Ludovic Vallier

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Early cell fate decisions of human embryonic stem cells and mouse epiblast stem cells are controlled by the same signalling pathways. by Ludovic Vallier, Thomas Touboul, Zhenzhi Chng, Minodora Brimpari, Nicholas Hannan, Enrique Millan, Lucy E Smithers, Matthew Trotter, Peter Rugg-Gunn, Anne Weber, Roger A Pedersen

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Successful Generation of Human Induced Pluripotent Stem Cell Lines from Blood Samples Held at Room Temperature for up to 48 hr by Chukwuma A. Agu, Filipa A.C. Soares, Alex Alderton, Minal Patel, Rizwan Ansari, Sharad Patel, Sally Forrest, Fengtang Yang, Jonathan Lineham, Ludovic Vallier, Christopher M. Kirton

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Combined single-cell profiling of expression and DNA methylation reveals splicing regulation and heterogeneity by Stephanie M. Linker, Lara Urban, Stephen J. Clark, Mariya Chhatriwala, Shradha Amatya, Davis J. McCarthy, Ingo Ebersberger, Ludovic Vallier, Wolf Reik, Oliver Stegle, Marc Jan Bonder

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Non-CG DNA methylation is a biomarker for assessing endodermal differentiation capacity in pluripotent stem cells by Lee M. Butcher, Mitsuteru Ito, Minodora Brimpari, Tiffany J. Morris, Filipa A. C. Soares, Lars Ährlund-Richter, Nessa Carey, Ludovic Vallier, Anne C. Ferguson-Smith, Stephan Beck

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An in vitro stem cell model of human epiblast and yolk sac interaction by Kirsty ML Mackinlay, Bailey AT Weatherbee, Viviane Souza Rosa, Charlotte E Handford, George Hudson, Tim Coorens, Lygia V Pereira, Sam Behjati, Ludovic Vallier, Marta N Shahbazi, Magdalena Zernicka-Goetz

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GATA6 Cooperates with EOMES/SMAD2/3 to Deploy the Gene Regulatory Network Governing Human Definitive Endoderm and Pancreas Formation by Crystal Y. Chia, Pedro Madrigal, Simon L.I.J. Denil, Iker Martinez, Jose Garcia-Bernardo, Ranna El-Khairi, Mariya Chhatriwala, Maggie H. Shepherd, Andrew T. Hattersley, N. Ray Dunn, Ludovic Vallier

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HNF4A Haploinsufficiency in MODY1 Abrogates Liver and Pancreas Differentiation from Patient-Derived Induced Pluripotent Stem Cells by Natasha Hui Jin Ng, Joanita Binte Jasmen, Chang Siang Lim, Hwee Hui Lau, Vidhya Gomathi Krishnan, Juned Kadiwala, Rohit N. Kulkarni, Helge Ræder, Ludovic Vallier, Shawn Hoon, Adrian Kee Keong Teo

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TGFβ signalling is required to maintain pluripotency of human naïve pluripotent stem cells by Anna Osnato, Stephanie Brown, Christel Krueger, Simon Andrews, Amanda J Collier, Shota Nakanoh, Mariana Quiroga Londoño, Brandon T Wesley, Daniele Muraro, A Sophie Brumm, Kathy K Niakan, Ludovic Vallier, Daniel Ortmann, Peter J Rugg-Gunn

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