The clinical and cost effectiveness of splints for thumb base osteoarthritis: a randomized controlled clinical trial de réir Adams, J, Barratt, P, Rombach, I, Arden, N, Barbosa Bouças, S, Bradley, S, Doherty, M, Dutton, SJ, Gooberman-Hill, R, Hislop-Lennie, K, Hutt-Greenyer, C, Jansen, V, Luengo-Fernadez, R, Williams, M, Dziedzic, K