Luigi Naldini
Luigi Naldini (born 1959 in Turin) is an Italian gene therapist, professor of cell and tissue biology and of gene and cell therapy at Vita-Salute San Raffaele University, and the director of San Raffaele Telethon Institute for Gene Therapy in Milan, Italy. Often considered as ''"the father of the lentivirus gene therapy"'', he is globally known as the pioneer of "the development and applications of lentiviral vectors for gene transfer" that allowed the gene therapy treatment of several genetic diseases. He is also a scientific co-founder of three biotech start-up companies, Genenta in Milan and New York, Chroma Medicine in Milan and Boston, Genespire in Milan. He is also the former president of European Society of Gene and Cell Therapy (ESGCT) and an elected member of European Molecular Biology Organization (EMBO). In 2019, he was awarded Louis-Jeantet Prize for Medicine "for taking gene therapy from the bench to the bedside". Provided by Wikipedia
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Genetic engineering of hematopoiesis: current stage of clinical translation and future perspectives by Luigi Naldini
Published 2019-03-01
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Dynamic Activity of miR-125b and miR-93 during Murine Neural Stem Cell Differentiation In Vitro and in the Subventricular Zone Neurogenic Niche. by Annalisa Lattanzi, Bernhard Gentner, Daniela Corno, Tiziano Di Tomaso, Pieter Mestdagh, Frank Speleman, Luigi Naldini, Angela Gritti
Published 2013-01-01
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Design of a regulated lentiviral vector for hematopoietic stem cell gene therapy of globoid cell leukodystrophy by Silvia Ungari, Annita Montepeloso, Francesco Morena, Fabienne Cocchiarella, Alessandra Recchia, Sabata Martino, Bernhard Gentner, Luigi Naldini, Alessandra Biffi
Published 2015-01-01
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S255: CELLULAR SENESCENCE AND INFLAMMATORY PROGRAMS ARE UNINTENDED CONSEQUENCES OF CRISPR-CAS9 GENE EDITING IN HEMATOPOIETIC STEM AND PROGENITOR CELLS by Anastasia Conti, Teresa Tavella, Rosaria De Marco, Federico Midena, Samuele Ferrari, Stefano Beretta, Chiara Brombin, Ivan Merelli, Luigi Naldini, Raffaella DI Micco
Published 2023-08-01
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Lentiviral vectors escape innate sensing but trigger p53 in human hematopoietic stem and progenitor cells by Francesco Piras, Michela Riba, Carolina Petrillo, Dejan Lazarevic, Ivan Cuccovillo, Sara Bartolaccini, Elia Stupka, Bernhard Gentner, Davide Cittaro, Luigi Naldini, Anna Kajaste‐Rudnitski
Published 2017-09-01
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Efficient Ex Vivo Engineering and Expansion of Highly Purified Human Hematopoietic Stem and Progenitor Cell Populations for Gene Therapy by Erika Zonari, Giacomo Desantis, Carolina Petrillo, Francesco E. Boccalatte, Maria Rosa Lidonnici, Anna Kajaste-Rudnitski, Alessandro Aiuti, Giuliana Ferrari, Luigi Naldini, Bernhard Gentner
Published 2017-04-01
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miR-511-3p Modulates Genetic Programs of Tumor-Associated Macrophages by Mario Leonardo Squadrito, Ferdinando Pucci, Laura Magri, Davide Moi, Gregor D. Gilfillan, Anna Ranghetti, Andrea Casazza, Massimiliano Mazzone, Robert Lyle, Luigi Naldini, Michele De Palma
Published 2012-02-01
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P1405: IN-DEPTH GENOME INTEGRITY EVALUATION AND GMP-COMPLIANT MANUFACTURING OF HDR GENE EDITED CD4+ T CELLS FOR THE TREATMENT OF HYPER IGM 1 by Daniele Canarutto, Claudia Asperti, Valentina Vavassori, Simona Porcellini, Elisabetta Rovelli, Marianna Paulis, Samuele Ferrari, Tiziana Plati, Lucia Sergi Sergi, Anna Villa, Marina Radrizzani, Luigi Naldini
Published 2023-08-01
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TIM-3, LAG-3, or 2B4 gene disruptions increase the anti-tumor response of engineered T cells by Beatrice Claudia Cianciotti, Zulma Irene Magnani, Alessia Ugolini, Barbara Camisa, Barbara Camisa, Ivan Merelli, Valentina Vavassori, Alessia Potenza, Antonio Imparato, Francesco Manfredi, Danilo Abbati, Laura Perani, Antonello Spinelli, Eric Shifrut, Eric Shifrut, Eric Shifrut, Fabio Ciceri, Fabio Ciceri, Luca Vago, Luca Vago, Raffaella Di Micco, Luigi Naldini, Luigi Naldini, Pietro Genovese, Pietro Genovese, Eliana Ruggiero, Chiara Bonini, Chiara Bonini
Published 2024-02-01
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Monitoring disease evolution and treatment response in lysosomal disorders by the peripheral benzodiazepine receptor ligand PK11195 by Ilaria Visigalli, Rosa Maria Moresco, Sara Belloli, Letterio S. Politi, Angela Gritti, Daniela Ungaro, Mario Matarrese, Elia Turolla, Andrea Falini, Giuseppe Scotti, Luigi Naldini, Ferruccio Fazio, Alessandra Biffi
Published 2009-04-01
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IFNα gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment by Mario Catarinella, Andrea Monestiroli, Giulia Escobar, Amleto Fiocchi, Ngoc Lan Tran, Roberto Aiolfi, Paolo Marra, Antonio Esposito, Federica Cipriani, Luca Aldrighetti, Matteo Iannacone, Luigi Naldini, Luca G Guidotti, Giovanni Sitia
Published 2016-02-01
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Interferon gene therapy reprograms the leukemia microenvironment inducing protective immunity to multiple tumor antigens by Giulia Escobar, Luigi Barbarossa, Giulia Barbiera, Margherita Norelli, Marco Genua, Anna Ranghetti, Tiziana Plati, Barbara Camisa, Chiara Brombin, Davide Cittaro, Andrea Annoni, Attilio Bondanza, Renato Ostuni, Bernhard Gentner, Luigi Naldini
Published 2018-07-01
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Myeloid cell‐based delivery of IFN‐γ reprograms the leukemia microenvironment and induces anti‐tumoral immune responses by Adele Mucci, Gabriele Antonarelli, Carolina Caserta, Francesco Maria Vittoria, Giacomo Desantis, Riccardo Pagani, Beatrice Greco, Monica Casucci, Giulia Escobar, Laura Passerini, Nico Lachmann, Francesca Sanvito, Matteo Barcella, Ivan Merelli, Luigi Naldini, Bernhard Gentner
Published 2021-10-01
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Laboratory-Scale Lentiviral Vector Production and Purification for Enhanced Ex Vivo and In Vivo Genetic Engineering by Monica Soldi, Lucia Sergi Sergi, Giulia Unali, Thomas Kerzel, Ivan Cuccovillo, Paola Capasso, Andrea Annoni, Mauro Biffi, Paola Maria Vittoria Rancoita, Alessio Cantore, Angelo Lombardo, Luigi Naldini, Mario Leonardo Squadrito, Anna Kajaste-Rudnitski
Published 2020-12-01
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P1373: UNCOVERING UPSIDES AND PITFALLS OF BASE AND PRIME EDITING IN HEMATOPOIETIC STEM CELLS by Martina Fiumara, Samuele Ferrari, Attya Omer-Javed, Stefano Beretta, Luisa Albano, Daniele Canarutto, Angelica Varesi, Chiara Gaddoni, Chiara Brombin, Federica Cugnata, Erika Zonari, Matteo Maria Naldini, Matteo Barcella, Bernhard Gentner, Ivan Merelli, Luigi Naldini
Published 2023-08-01
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Liver-directed lentiviral gene therapy corrects hemophilia A mice and achieves normal-range factor VIII activity in non-human primates by Michela Milani, Cesare Canepari, Tongyao Liu, Mauro Biffi, Fabio Russo, Tiziana Plati, Rosalia Curto, Susannah Patarroyo-White, Douglas Drager, Ilaria Visigalli, Chiara Brombin, Paola Albertini, Antonia Follenzi, Eduard Ayuso, Christian Mueller, Andrea Annoni, Luigi Naldini, Alessio Cantore
Published 2022-05-01
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Multiple Integrated Non-clinical Studies Predict the Safety of Lentivirus-Mediated Gene Therapy for β-Thalassemia by Maria Rosa Lidonnici, Ylenia Paleari, Francesca Tiboni, Giacomo Mandelli, Claudia Rossi, Michela Vezzoli, Annamaria Aprile, Carsten Werner Lederer, Alessandro Ambrosi, Franck Chanut, Francesca Sanvito, Andrea Calabria, Valentina Poletti, Fulvio Mavilio, Eugenio Montini, Luigi Naldini, Patrizia Cristofori, Giuliana Ferrari
Published 2018-12-01
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