Understanding the Spatial Topology of Artificial Immunological Synapses Assembled in T Cell-Redirecting Strategies: A Major Issue in Cancer Immunotherapy by Pedro Roda-Navarro, Pedro Roda-Navarro, Luis Álvarez-Vallina, Luis Álvarez-Vallina

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Engineered mRNA and the Rise of Next-Generation Antibodies by Laura Sanz, Luis Álvarez-Vallina

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Engineering Immune Cells for in vivo Secretion of Tumor-Specific T Cell-Redirecting Bispecific Antibodies by Belén Blanco, Belén Blanco, Ángel Ramírez-Fernández, Ángel Ramírez-Fernández, Luis Alvarez-Vallina, Luis Alvarez-Vallina

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Bi- and trispecific immune cell engagers for immunotherapy of hematological malignancies by Antonio Tapia-Galisteo, Luis Álvarez-Vallina, Laura Sanz

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Lymphocyte display: a novel antibody selection platform based on T cell activation. by Vanesa Alonso-Camino, David Sánchez-Martín, Marta Compte, Laura Sanz, Luis Alvarez-Vallina

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Bispecific Antibody Format and the Organization of Immunological Synapses in T Cell-Redirecting Strategies for Cancer Immunotherapy by Carlos Carrasco-Padilla, Alicia Hernaiz-Esteban, Luis Álvarez-Vallina, Oscar Aguilar-Sopeña, Pedro Roda-Navarro

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CARbodies: Human Antibodies Against Cell Surface Tumor Antigens Selected From Repertoires Displayed on T Cell Chimeric Antigen Receptors by Vanesa Alonso-Camino, David Sánchez-Martín, Marta Compte, Natalia Nuñez-Prado, Rosa M Diaz, Richard Vile, Luis Alvarez-Vallina

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In vivo tumor targeting and imaging with engineered trivalent antibody fragments containing collagen-derived sequences. by Angel M Cuesta, David Sánchez-Martín, Laura Sanz, Jaume Bonet, Marta Compte, Leonor Kremer, Francisco J Blanco, Baldomero Oliva, Luis Alvarez-Vallina

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Synapse topology and downmodulation events determine the functional outcome of anti-CD19 T cell-redirecting strategies by Ángel Ramírez-Fernández, Óscar Aguilar-Sopeña, Laura Díez-Alonso, Alejandro Segura-Tudela, Carmen Domínguez-Alonso, Pedro Roda-Navarro, Luis Álvarez-Vallina, Belén Blanco

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The heterotrimeric laminin coiled-coil domain exerts anti-adhesive effects and induces a pro-invasive phenotype. by Patricia Santos-Valle, Irene Guijarro-Muñoz, Angel M Cuesta, Vanesa Alonso-Camino, Maider Villate, Ana Alvarez-Cienfuegos, Francisco J Blanco, Laura Sanz, Luis Alvarez-Vallina

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Programmable half-life and anti-tumour effects of bispecific T-cell engager-albumin fusions with tuned FcRn affinity by Ole A. Mandrup, Sui Ching Ong, Simon Lykkemark, Anders Dinesen, Imke Rudnik-Jansen, Niels Frederik Dagnæs-Hansen, Jan Terje Andersen, Luis Alvarez-Vallina, Kenneth A. Howard

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Combination of T cell-redirecting strategies with a bispecific antibody blocking TGF-β and PD-L1 enhances antitumor responses by Antonio Tapia-Galisteo, Iñigo Sánchez-Rodríguez, Javier Narbona, Patricia Iglesias-Hernández, Saray Aragón-García, Anaïs Jiménez-Reinoso, Marta Compte, Shaukat Khan, Takeshi Tsuda, Patrick Chames, Javier Lacadena, Luis Álvarez-Vallina, Laura Sanz

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TGF‐β‐induced IGFBP‐3 is a key paracrine factor from activated pericytes that promotes colorectal cancer cell migration and invasion by Rocío Navarro, Antonio Tapia‐Galisteo, Laura Martín‐García, Carlos Tarín, Cesáreo Corbacho, Gonzalo Gómez‐López, Esther Sánchez‐Tirado, Susana Campuzano, Araceli González‐Cortés, Paloma Yáñez‐Sedeño, Marta Compte, Luis Álvarez‐Vallina, Laura Sanz

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Efficient preclinical treatment of cortical T cell acute lymphoblastic leukemia with T lymphocytes secreting anti-CD1a T cell engagers by Pablo Menendez, Diego Sánchez Martínez, Néstor Tirado, Alba Martínez-Moreno, Anaïs Jiménez-Reinoso, Víctor M Díaz, Marina García-Peydró, Oana Hangiu, Laura Díez-Alonso, Ángela Albitre, Petronila Penela, Maria L Toribio, Luis Álvarez-Vallina

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Basement membrane-rich organoids with functional human blood vessels are permissive niches for human breast cancer metastasis. by Rodrigo Fernández-Periáñez, Irene Molina-Privado, Federico Rojo, Irene Guijarro-Muñoz, Vanesa Alonso-Camino, Sandra Zazo, Marta Compte, Ana Alvarez-Cienfuegos, Angel M Cuesta, David Sánchez-Martín, Ana M Alvarez-Méndez, Laura Sanz, Luis Alvarez-Vallina

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Trispecific T-cell engagers for dual tumor-targeting of colorectal cancer by Antonio Tapia-Galisteo, Íñigo Sánchez Rodríguez, Oscar Aguilar-Sopeña, Seandean Lykke Harwood, Javier Narbona, Mariola Ferreras Gutierrez, Rocío Navarro, Laura Martín-García, Cesáreo Corbacho, Marta Compte, Javier Lacadena, Francisco J. Blanco, Patrick Chames, Pedro Roda-Navarro, Luis Álvarez-Vallina, Laura Sanz

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ATTACK, a novel bispecific T cell-recruiting antibody with trivalent EGFR binding and monovalent CD3 binding for cancer immunotherapy by Seandean Lykke Harwood, Ana Alvarez-Cienfuegos, Natalia Nuñez-Prado, Marta Compte, Sara Hernández-Pérez, Nekane Merino, Jaume Bonet, Rocio Navarro, Paul M. P. Van Bergen en Henegouwen, Simon Lykkemark, Kasper Mikkelsen, Kasper Mølgaard, Frederic Jabs, Laura Sanz, Francisco J. Blanco, Pedro Roda-Navarro, Luis Alvarez-Vallina

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Tumor targeted 4-1BB agonist antibody-albumin fusions with high affinity to FcRn induce anti-tumor immunity without toxicity by Oana Hangiu, Marta Compte, Anders Dinesen, Rocio Navarro, Antonio Tapia-Galisteo, Ole A. Mandrup, Ainhoa Erce-Llamazares, Rodrigo Lázaro-Gorines, Daniel Nehme-Álvarez, Carmen Domínguez-Alonso, Seandean L. Harwood, Carlos Alfonso, Belen Blanco, Laura Rubio-Pérez, Anaïs Jiménez-Reinoso, Laura Díez-Alonso, Francisco J. Blanco, Laura Sanz, Kenneth A. Howard, Luis Álvarez-Vallina

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10th antibody industrial symposium: new developments in antibody and adoptive cell therapies by Ana Antunes, Luis Alvarez-Vallina, Federico Bertoglio, Nicolas Bouquin, Stéphanie Cornen, Francis Duffieux, Pierre Ferré, Raphaëlle Gillet, Christian Jorgensen, Mark B Leick, Bernard Maillère, Hélène Negre, Mireia Pelegrin, Nicolas Poirier, Dietmar Reusch, Bruno Robert, Guy Serre, Alain Vicari, Martin Villalba, Christoph Volpers, Gavin Vuddamalay, Hervé Watier, Thierry Wurch, Lennart Zabeau, Stefan Zielonka, Baolin Zhang, Alain Beck, Pierre Martineau

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A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity by Marta Compte, Seandean Lykke Harwood, Ines G. Muñoz, Rocio Navarro, Manuela Zonca, Gema Perez-Chacon, Ainhoa Erce-Llamazares, Nekane Merino, Antonio Tapia-Galisteo, Angel M. Cuesta, Kasper Mikkelsen, Eduardo Caleiras, Natalia Nuñez-Prado, M. Angela Aznar, Simon Lykkemark, Jorge Martínez-Torrecuadrada, Ignacio Melero, Francisco J. Blanco, Jorge Bernardino de la Serna, Juan M. Zapata, Laura Sanz, Luis Alvarez-Vallina

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