A highly focused antigen receptor repertoire characterizes γδ T cells that are poised to make IL-17 rapidly in naive animals 著者: Yu-Ling eWei, Arnold eHan, Jacob eGlanville, Fengqin eFang, Luis Alejandro Zuniga, Jacob eLee, Daniel eCua, Yueh-Hsiu eChien, Yueh-Hsiu eChien

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Intratumoral delivery of TransCon™ TLR7/8 Agonist promotes sustained anti-tumor activity and local immune cell activation while minimizing systemic cytokine induction 著者: Luis Alejandro Zúñiga, Torben Leßmann, Karan Uppal, Nicola Bisek, Enping Hong, Caroline E. Rasmussen, Jens-Jakob Karlsson, Joachim Zettler, Lars Holten-Andersen, Kathy Bang, Dhruv Thakar, Yu-Chi Lee, Salomon Martinez, Simran Singh Sabharwal, Sebastian Stark, Frank Faltinger, Oliver Kracker, Samuel Weisbrod, Robin Müller, Tobias Voigt, Kornelia Bigott, Mohammad Tabrizifard, Vibeke Miller Breinholt, Amer M. Mirza, David B. Rosen, Kennett Sprogøe, Juha Punnonen

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TransCon IL-2 β/γ: a novel long-acting prodrug with sustained release of an IL-2Rβ/γ-selective IL-2 variant with improved pharmacokinetics and potent activation of cytotoxic immune... 著者: Anne Månsson Kvarnhammar, Juha Punnonen, Enping Hong, Diana Reich, Karan Uppal, Kathy Bang, David B Rosen, Burkhardt Laufer, Thomas Knappe, Jens Jakob Karlsson, Yu-Chi Lee, Dhruv Thakar, Luis Alejandro Zúñiga, Simran Singh Sabharwal, Janne Damm Olling, Kristian Kjaergaard, Thomas Kurpiers, Meike Schnabel, Philipp Glock, Joachim Zettler, Mathias Krusch, Ana Bernhard, Stefan Heinig, Valentino Konjik, Thomas Wegge, Yvonne Hehn, Steffen Killian, Laura Viet, Josefine Runz, Frank Faltinger, Mohammad Tabrizi, Kristin Laura Abel, Vibeke Miller Breinholt, Stina M Singel, Kennett Sprogøe

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