Epoxy-α-lapachone (2,2-Dimethyl-3,4-dihydro-spiro[2H-naphtho[2,3-b]pyran-10,2′-oxirane]-5(10H)-one): a promising molecule to control infections caused by protozoan parasites by Juliana Figueiredo Peixoto, Adriane da Silva Oliveira, Luiz Filipe Gonçalves - Oliveira, Franklin Souza - Silva, Carlos Roberto Alves

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In Silico Insights into the Mechanism of Action of Epoxy-α-Lapachone and Epoxymethyl-Lawsone in <i>Leishmania</i> spp. by Juliana Figueiredo Peixoto, Adriane da Silva Oliveira, Patrícia Queiroz Monteiro, Luiz Filipe Gonçalves-Oliveira, Valter Viana Andrade-Neto, Vitor Francisco Ferreira, Franklin Souza-Silva, Carlos Roberto Alves

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Antileishmanial Activity of 2-Methoxy-4H-spiro-[naphthalene-1,2′-oxiran]-4-one (Epoxymethoxy-lawsone): A Promising New Drug Candidate for Leishmaniasis Treatment by Luiz Filipe Gonçalves Oliveira, Franklin Souza-Silva, Luzia Monteiro de Castro Côrtes, Lea Cysne-Finkelstein, Mirian Cláudia de Souza Pereira, Francisco Odêncio de Oliveira Junior, Rosa Teixeira Pinho, Suzana Corte Real, Saulo Cabral Bourguignon, Vitor Francisco Ferreira, Carlos Roberto Alves

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Efficacy of the treatment using a microemulsion loaded with epoxy-α-lapachone in combination with meglumine antimoniate against murine infection by Leishmania (Leishmania) amazonen... by Juliana Figueiredo Peixoto, Luiz Filipe Gonçalves-Oliveira, Franklin Souza-Silva, Luzia Monteiro de Castro Côrtes, Léa Cysne Finkelstein, Geovane Dias-Lopes, Beatriz Ferreira de Carvalho Patricio, Carolina Guimarães de Souza Lima, Helvécio Vinícius Antunes Rocha, Fernando de Carvalho da Silva, Vitor Francisco Ferreira, Bernardo Acácio Santini Pereira, Carlos Roberto Alves

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The combination therapy of meglumine antimoniate and oxiranes (epoxy-α-lapachone and epoxymethyl-lawsone) enhance the leishmanicidal effect in mice infected by Leishmania (Leishman... by Luiz Filipe Gonçalves-Oliveira, Ph.D., Franklin Souza-Silva, Ph.D., Luzia Monteiro de Castro Côrtes, Ph.D., Laura Barral Veloso, Ph.D., Bernardo Acácio Santini Pereira, Ph.D., Lea Cysne-Finkelstein, Ph.D., Guilherme Curty Lechuga, Ph.D., Saulo Cabral Bourguignon, Ph.D., Fernando Almeida-Souza, Ph.D., Kátia da Silva Calabrese, Ph.D., Vitor Francisco Ferreira, Ph.D., Carlos Roberto Alves, Ph.D.

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