Rocking the world of innate immunity: an interview with Luke O'Neill by Luke A. J. O'Neill

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A Metabolic Roadblock in Inflammatory Macrophages by Luke A.J. O’Neill

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Can NLRP3 inhibitors improve on dexamethasone for the treatment of COVID-19? by Alexander Hooftman, Luke A.J. O'Neill

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Targeting mitochondrial metabolites and nucleic acids as an anti-inflammatory strategy by Yukun Min, Luke A. J. O’Neill

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A Role for the Krebs Cycle Intermediate Citrate in Metabolic Reprogramming in Innate Immunity and Inflammation by Niamh C. Williams, Luke A. J. O’Neill

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Correction: The Cytokine Release Inhibitory Drug CRID3 Targets ASC Oligomerisation in the NLRP3 and AIM2 Inflammasomes. by Rebecca C. Coll, Luke A. J. O'Neill

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The role of itaconate in host defense and inflammation by Christian G. Peace, Luke A.J. O’Neill

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How neutrophil metabolism affects bacterial killing by Juliana E. Toller-Kawahisa, Luke A. J. O'Neill

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Metabolic reprogramming in macrophage polarization by Silvia eGalván-Peña, Luke A.J. O'Neill

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An Emerging Role for Type I Interferons as Critical Regulators of Blood Coagulation by Tristram A. J. Ryan, Luke A. J. O’Neill

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MicroRNA-21 Limits Uptake of Listeria monocytogenes by Macrophages to Reduce the Intracellular Niche and Control Infection by Daniel G. W. Johnston, Daniel G. W. Johnston, Jay Kearney, Zbigniew Zasłona, Michelle A. Williams, Luke A. J. O'Neill, Sinéad C. Corr

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Both TLR2 and TRIF contribute to interferon-β production during Listeria infection. by Camille Aubry, Sinéad C Corr, Sebastian Wienerroither, Céline Goulard, Ruth Jones, Amanda M Jamieson, Thomas Decker, Luke A J O'Neill, Olivier Dussurget, Pascale Cossart

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A dimer of the Toll-like receptor 4 cytoplasmic domain provides a specific scaffold for the recruitment of signalling adaptor proteins. by Ricardo Núñez Miguel, Joyce Wong, Julian F Westoll, Heather J Brooks, Luke A J O'Neill, Nicholas J Gay, Clare E Bryant, Tom P Monie

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ACLY Nuclear Translocation in Human Macrophages Drives Proinflammatory Gene Expression by NF-κB Acetylation by Anna Santarsiero, Paolo Convertini, Simona Todisco, Ciro L. Pierri, Anna De Grassi, Niamh C. Williams, Dominga Iacobazzi, Giulio De Stefano, Luke A. J. O’Neill, Vittoria Infantino

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Loss of the molecular clock in myeloid cells exacerbates T cell-mediated CNS autoimmune disease by Caroline E. Sutton, Conor M. Finlay, Mathilde Raverdeau, James O. Early, Joseph DeCourcey, Zbigniew Zaslona, Luke A. J. O’Neill, Kingston H. G. Mills, Annie M. Curtis

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C5aR2 Regulates STING-Mediated Interferon Beta Production in Human Macrophages by Oliver Wright, Anna Harris, Van Dien Nguyen, You Zhou, Maxim Durand, Abbie Jayyaratnam, Darren Gormley, Luke A. J. O’Neill, Kathy Triantafilou, Eva Maria Nichols, Lee M. Booty

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Characterization and inhibition of inflammasome responses in severe and non-severe asthma by Jay C. Horvat, Richard Y. Kim, Natasha Weaver, Christopher Augood, Alexandra C. Brown, Chantal Donovan, Pierrick Dupre, Lakshitha Gunawardhana, Jemma R. Mayall, Nicole G. Hansbro, Avril A. B. Robertson, Luke A. J. O’Neill, Matthew A. Cooper, Elizabeth G. Holliday, Philip M. Hansbro, Peter G. Gibson

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Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy by Eunice E. To, Ross Vlahos, Raymond Luong, Michelle L. Halls, Patrick C. Reading, Paul T. King, Christopher Chan, Grant R. Drummond, Christopher G. Sobey, Brad R. S. Broughton, Malcolm R. Starkey, Renee van der Sluis, Sharon R. Lewin, Steven Bozinovski, Luke A. J. O’Neill, Tim Quach, Christopher J. H. Porter, Doug A. Brooks, John J. O’Leary, Stavros Selemidis

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Endogenously produced itaconate negatively regulates innate-driven cytokine production and drives global ubiquitination in human macrophages by Luke A. Bourner, Linda A. Chung, Haiyan Long, Anne F. McGettrick, Junpeng Xiao, Kenneth Roth, Jade D. Bailey, Marie Strickland, Bo Tan, Jason Cunningham, Barry Lutzke, James McGee, Francella J. Otero, David C. Gemperline, Lin Zhang, Ying C. Wang, Michael J. Chalmers, Chiao-Wen Yang, Jesus A. Gutierrez, Luke A.J. O’Neill, Frank C. Dorsey

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Nrf2 activation reprograms macrophage intermediary metabolism and suppresses the type I interferon response by Dylan G. Ryan, Elena V. Knatko, Alva M. Casey, Jens L. Hukelmann, Sharadha Dayalan Naidu, Alejandro J. Brenes, Thanapon Ekkunagul, Christa Baker, Maureen Higgins, Laura Tronci, Efterpi Nikitopolou, Tadashi Honda, Richard C. Hartley, Luke A.J. O’Neill, Christian Frezza, Angus I. Lamond, Andrey Y. Abramov, J. Simon C. Arthur, Doreen A. Cantrell, Michael P. Murphy, Albena T. Dinkova-Kostova

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