Bisphosphonate affinity to hydroxyapatite and farnesyl pyrophosphate inhibitory potency, together, drive in vivo efficacy by Lundy, M, Ebetino, F, Fei, L, Xia, Z, Pozzi, M, Trokhan, D, Phipps, R, Dunford, J, Triffitt, J, Russell, R

The mode of binding of nitrogen containing bisphosphonates in farnesyl pyrophosphate synthase by Ebetino, F, Dunford, J, Lundy, M, Dao, X, Dobson, R, Triffitt, J, Quijano, M, Song, X, Boeckman, R, Russell, R, Barnett, B

Bone mineral affinity influences the distribution of a bisphosphonate and a lower affinity analogue in vivo by Roelofs, A, Boyde, A, Lundy, M, McKenna, C, Blazewska, K, Sun, S, Kashemirov, B, Russell, R, Ebetino, F, Rogers, M, Coxon, F

Influence of bone affinity on the skeletal distribution of fluorescently labeled bisphosphonates in vivo. by Roelofs, A, Stewart, C, Sun, S, Błażewska, K, Kashemirov, B, McKenna, C, Russell, R, Rogers, M, Lundy, M, Ebetino, F, Coxon, F

The Successful Design Of A Novel Highly Potent Nitrogen-Containing Bisphosphonate With Lower Bone Affinity. by Ebetino, F, Ebetino, F, Lundy, M, Kwaasi, A, Dunford, J, Duan, X, Triffitt, J, Mazur, A, Jeans, G, Barnett, B, Russell, R

The Ability of Bisphosphonates and Their Analogues to Penetrate the Osteocyte Network is Dependent on Affinity for Bone by Roelofs, A, Boyde, A, Lundy, M, McKenna, C, Blazewska, K, Sun, S, Kashemirov, B, Duan, X, Russell, G, Khalid, A, Rogers, M, Ebetino, F

Molecular modeling comparison of nitrogen-containing bisphosphonates of varying potency co-crystalized in farnesyl diphosphate synthase by Ebetino, F, Kashemitov, B, McKenna, C, Evdokimov, A, Pokross, M, Barnett, B, Dunford, J, Kavanagh, K, Rogers, M, Lundy, M, Opperman, U, Russell, R

Molecular modeling comparison of nitrogen-containing bisphosphonates of varying potency co-crystalized in farnesyl diphosphate synthase by Ebetino, F, Kashemirov, B, McKenna, C, Evdokimov, A, Pokross, M, Barnett, B, Dunford, J, Kavanagh, K, Rogers, M, Lundy, M, Oppermann, U, Russell, R

Fluorescently labeled risedronate and related analogs: Design and evaluation as imaging probes by Coxon, F, Bala, J, Kashemirov, B, Lundy, M, Chen, X, Xia, Z, Dunford, J, Russell, G, Roelofs, A, Rogers, M, McKenna, C, Ebetino, F

Fluorescently labeled risedronate and related analocs: Design and evaluation as imaging probes by Coxon, F, Bala, J, Kashemirov, B, Roelofs, A, Lundy, M, Chen, X, Xia, Z, Dunford, J, Russell, R, Rogers, M, McKenna, C, Ebetino, F

A mirror image pair of bisphosphonate analogs further demonstrates the mode of binding of the bisphosphonates in farnesyl pyrophosphate synthase by Ebetino, F, Dunford, J, Lundy, M, Pozzi, M, Xia, Z, Dobson, R, Quijano, M, Christian, R, Kashemirov, B, McKenna, C, Russell, G, Barnett, B

Bisphosphonate binding affinity affects drug distribution in both intracortical and trabecular bone of rabbits. by Turek, J, Ebetino, F, Lundy, M, Sun, S, Kashemirov, B, McKenna, C, Gallant, M, Plotkin, L, Bellido, T, Duan, X, Triffitt, J, Russell, R, Burr, D, Allen, MR

Bisphosphonates: an update on mechanisms of action and how these relate to clinical efficacy. by Russell, R, Xia, Z, Dunford, J, Oppermann, U, Kwaasi, A, Hulley, P, Kavanagh, K, Triffitt, J, Lundy, M, Phipps, R, Barnett, B, Coxon, F, Rogers, M, Watts, N, Ebetino, F

The relationship between the chemistry and biological activity of the bisphosphonates. by Ebetino, F, Hogan, A, Sun, S, Tsoumpra, M, Duan, X, Triffitt, J, Kwaasi, A, Dunford, J, Barnett, B, Oppermann, U, Lundy, M, Boyde, A, Kashemirov, B, McKenna, C, Russell, R

Bisphosphonates: an update on mechanisms of action and how these relate to clinical efficacy. by Russell, R, Xia, Z, Dunford, J, Oppermann, U, Kwaasi, A, Hulley, P, Kavanagh, K, Triffitt, J, Lundy, M, Phipps, R, Barnett, B, Coxon, F, Rogers, M, Watts, N, Ebetino, F

Synthesis, chiral high performance liquid chromatographic resolution and enantiospecific activity of a potent new geranylgeranyl transferase inhibitor, 2-hydroxy-3-imidazo[1,2-a]py... by McKenna, C, Kashemirov, B, Błazewska, K, Mallard-Favier, I, Stewart, C, Rojas, J, Lundy, M, Ebetino, F, Baron, R, Dunford, J, Kirsten, M, Seabra, M, Bala, J, Marma, MS, Rogers, M, Coxon, F

The pharmacological profile of a novel highly potent bisphosphonate, OX14 (1-Fluoro-2-(Imidazo-[1,2-α]Pyridin-3-yl)-Ethyl-Bisphosphonate) by Lawson, M, Ebetino, F, Mazur, A, Chantry, A, Paton-Hough, J, Evans, H, Lath, D, Tsoumpra, M, Lundy, M, Dobson, R, Quijano, M, Kwaasi, A, Dunford, J, Duan, X, Triffitt, J, Jeans, G, Russell, R