The OA thumb therapy trial: a three arm multi-centre randomised controlled trial of the clinical effectiveness and efficacy of splints for symptomatic thumb base OA by Adams, J, Barratt, P, Arden, NK, Boucas, SB, Bradley, S, Doherty, M, Dutton, S, Dziedzic, K, Gooberman-Hill, R, Hislop, K, Hutt-Greenyer, C, Jansen, V, Lunego, R, Rombach, I, Wiliams, M