Editorial: Malaria molecular epidemiology current situation in Africa by Kwesi Zandoh Tandoh, Nancy Odurowah Duah-Quashie, Jaishree Raman, Lynette Isabella Ochola-Oyier

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Temporal trends in prevalence of Plasmodium falciparum drug resistance alleles over two decades of changing antimalarial policy in coastal Kenya by John Okombo, Alice W. Kamau, Kevin Marsh, Colin J. Sutherland, Lynette Isabella Ochola-Oyier

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A cross-sectional analysis identifies a low prevalence of Plasmodium ovale species infections in symptomatic and asymptomatic individuals in Kilifi county, Kenya. [version 4; peer... by Leonard Ndwiga, Mercy Yvonne Akinyi, Kelvin Muteru Kimenyi, Margaret Chifwete, Victor Osoti, Lynette Isabella Ochola-Oyier

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ONT sequencing identifies a high prevalence of crt sensitive, triple mutant dhfr and single mutant dhps parasites within an ANC population in Nigeria by Adebanjo Jonathan Adegbola, Adebanjo Jonathan Adegbola, Leonard Ndwiga, Kevin Wamae, Victor Osoti, Oluseye Oladotun Bolaji, Philip Bejon, Lynette Isabella Ochola-Oyier

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Low frequency of Plasmodium falciparum hrp2/3 deletions from symptomatic infections at a primary healthcare facility in Kilifi, Kenya by Dorcas Okanda, Leonard Ndwiga, Victor Osoti, Nicole Achieng, Juliana Wambua, Caroline Ngetsa, Peter Lubell-Doughtie, Anuraj Shankar, Philip Bejon, Philip Bejon, Lynette Isabella Ochola-Oyier

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Extracellular vesicles could be a putative posttranscriptional regulatory mechanism that shapes intracellular RNA levels in Plasmodium falciparum by Mwikali Kioko, Alena Pance, Shaban Mwangi, David Goulding, Alison Kemp, Martin Rono, Lynette Isabella Ochola-Oyier, Pete C. Bull, Philip Bejon, Julian C. Rayner, Abdirahman I. Abdi

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Validation of saline, PBS and a locally produced VTM at varying storage conditions to detect the SARS-CoV-2 virus by qRT-PCR by Caroline Ngetsa, Victor Osoti, Dorcas Okanda, Faith Marura, Krupali Shah, Henry Karanja, Daisy Mugo, John Gitonga, Martin Mutunga, Clement Lewa, Benedict Orindi, Philip Bejon, Lynette Isabella Ochola-Oyier

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Validation of saline, PBS and a locally produced VTM at varying storage conditions to detect the SARS-CoV-2 virus by qRT-PCR. by Caroline Ngetsa, Victor Osoti, Dorcas Okanda, Faith Marura, Krupali Shah, Henry Karanja, Daisy Mugo, John Gitonga, Martin Mutunga, Clement Lewa, Benedict Orindi, Philip Bejon, Lynette Isabella Ochola-Oyier

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Distinct transcriptomic signatures define febrile malaria depending on initial infective states, asymptomatic or uninfected by Kelvin M. Kimenyi, Mercy Y. Akinyi, Kioko Mwikali, Tegan Gilmore, Shaban Mwangi, Elisha Omer, Bonface Gichuki, Juliana Wambua, James Njunge, George Obiero, Philip Bejon, Jean Langhorne, Abdirahman Abdi, Lynette Isabella Ochola-Oyier

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Detection of low frequency artemisinin resistance mutations, C469Y, P553L and A675V, and fixed antifolate resistance mutations in asymptomatic primary school children in Kenya by Victor Osoti, Kevin Wamae, Leonard Ndwiga, Paul M. Gichuki, Collins Okoyo, Stella Kepha, Kibor Keitany, Regina Kandie, Stephen Aricha, Rosebella Kiplagat, Charles Mwandawiro, Philip Bejon, Robert W. Snow, Lynette Isabella Ochola-Oyier

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Targeted Next Generation Sequencing for malaria research in Africa: current status and outlook by Anita Ghansah, Edwin Kamau, Alfred Amambua-Ngwa, Deus S. Ishengoma, Oumou Maiga-Ascofare, Lucas Amenga-Etego, Awa Deme, William Yavo, Milijaona Randrianarivelojosia, Plasmodium Diversity Network Africa, Lynette Isabella Ochola-Oyier, Gideon Kofi Helegbe, Jeffery Bailey, Michael Alifrangis, Abdoulaye Djimde

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New SARS-CoV-2 Omicron Variant with Spike Protein Mutation Y451H, Kilifi, Kenya, March–May 2023 by Mike J. Mwanga, Arnold W. Lambisia, John Mwita Morobe, Nickson Murunga, Edidah Moraa, Leonard Ndwiga, Robinson Cheruiyot, Jennifer Musyoki, Martin Mutunga, Laura M. Guzman-Rincon, Charles Sande, Joseph Mwangangi, Philip Bejon, Lynette Isabella Ochola-Oyier, D. James Nokes, Charles N. Agoti, Joyce Nyiro, George Githinji

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Temporal distribution and clinical characteristics of the Alpha, Delta and Omicron SARS-CoV-2 variants of concern in Laikipia, Kenya: institutional and community-based genomic surv... by Mr Arnold Lambisia, Mr Godfrey Mudhune, John M Morobe, Khadija Said Mohammed, O Timothy, Leonard Ndwiga, Maureen W Mburu, Edidah O Moraa, Jeniffer Musyoki, Nickson Murunga, Isaac N Waliaula, Arthur K Mumelo, Philip Bejon, Lynette Isabella Ochola-Oyier, George Githinji, Prof James Nokes, Mr Charles Agoti

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Epidemiology of COVID-19 infections on routine polymerase chain reaction (PCR) and serology testing in Coastal Kenya [version 1; peer review: 2 approved] by Henry Karanja, Daisy Mugo, D.J. Nokes, James Nyagwange, Lynette Isabella Ochola-Oyier, Kelvin Muteru, Leonard Ndwiga, Bernadette Kutima, Patrick Amoth, George Githinji, Kevin Wamae, Kadondi Kasera, Nickson Murunga, Lawrence Babu, Edwine Barasa, John Gitonga, Benjamin Tsofa, Philip Bejon, George Warimwe, James Tuju, Benedict Orindi, Charles N. Agoti, COVID testing team, Edward Otieno

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Kinetics of naturally induced binding and neutralising anti-SARS-CoV-2 antibody levels and potencies among SARS-CoV-2 infected Kenyans with diverse grades of COVID-19 severity: an... by Mansoor Saleh, Reena Shah, Linda Moranga, Ann Karanu, Jasmit Shah, Viviane Oluoch, Henry Karanja, Alfred Mburu, Julius Mutiso, Peter Betti, Daisy Mugo, Zaitun Nneka, Abdirahman Issak Abdi, Wanzila Usyu Mutinda, George M.Warimwe, Lynette Isabella Ochola-Oyier, James Nyagwange, Yiakon Sein, Francis M. Ndungu, Bernadette Kutima, John N. Gitonga, Philip Bejon, Perpetual Wanjiku, Eunice W. Nduati, Jedidah Mwacharo, Kennedy Mwai, Shahin Sayed, John Kimotho

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Transmission networks of SARS-CoV-2 in Coastal Kenya during the first two waves: A retrospective genomic study by Charles N Agoti, Lynette Isabella Ochola-Oyier, Simon Dellicour, Khadija Said Mohammed, Arnold W Lambisia, Zaydah R de Laurent, John M Morobe, Maureen W Mburu, Donwilliams O Omuoyo, Edidah M Ongera, Leonard Ndwiga, Eric Maitha, Benson Kitole, Thani Suleiman, Mohamed Mwakinangu, John K Nyambu, John Otieno, Barke Salim, Jennifer Musyoki, Nickson Murunga, Edward Otieno, John N Kiiru, Kadondi Kasera, Patrick Amoth, Mercy Mwangangi, Rashid Aman, Samson Kinyanjui, George Warimwe, My Phan, Ambrose Agweyu, Matthew Cotten, Edwine Barasa, Benjamin Tsofa, D James Nokes, Philip Bejon, George Githinji

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Genomic Epidemiology of SARS-CoV-2 in Seychelles, 2020–2021 by John Mwita Morobe, Brigitte Pool, Lina Marie, Dwayne Didon, Arnold W. Lambisia, Timothy Makori, Khadija Said Mohammed, Zaydah R. de Laurent, Leonard Ndwiga, Maureen W. Mburu, Edidah Moraa, Nickson Murunga, Jennifer Musyoki, Jedida Mwacharo, Lydia Nyamako, Debra Riako, Pariken Ephnatus, Faith Gambo, Josephine Naimani, Joyce Namulondo, Susan Zimba Tembo, Edwin Ogendi, Thierno Balde, Fred Athanasius Dratibi, Ali Ahmed Yahaya, Nicksy Gumede, Rachel A. Achilla, Peter K. Borus, Dorcas W. Wanjohi, Sofonias K. Tessema, Joseph Mwangangi, Philip Bejon, David J. Nokes, Lynette Isabella Ochola-Oyier, George Githinji, Leon Biscornet, Charles N. Agoti

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An optimization of four SARS-CoV-2 qRT-PCR assays in a Kenyan laboratory to support the national COVID-19 rapid response teams [version 2; peer review: 2 approved] by Shadrack Mutua, Brian Bartilol, Shaban J. Mwangi, Debra Riako, Lydia Nyamako, Bonface M. Gichuki, Henry Karanja, Angela Karani, John N. Gitonga, Daisy Mugo, Brian Tawa, Wilson Gumbi, Wesley Cheruiyot, Metrine Tendwa, John K. Nyambu, Yiakon Sein, Thani Suleiman Thani, Shem O. Patta, Benson Kitole, Eric K. Maitha, Barke S. Muslih, Mohamed S. Mwakinangu, Philip Bejon, Benjamin Tsofa, Joyce U. Nyiro, John Ochieng Otieno, Leonard Ndwiga, Patience Kiyuka, Johnstone Makale, Kevin Wamae, Victor Osoti, John Mwita Morobe, Calleb Odundo, Arnold W. Lambisia, Martin Mutunga, Salim Mwarumba, Lynette Isabella Ochola-Oyier, Charles N. Agoti, Clement Lewa, Elijah Gicheru, Jennifer Musyoki, Susan Njuguna, Horace Gumba, Domtila Kimani, Jedidah Mwacharo, Zaydah R. de Laurent, Khadija Said Mohammed, Robinson Cheruiyot, Donwilliams O. Omuoyo

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Maintaining laboratory quality assurance and safety in a pandemic: Experiences from the KEMRI-Wellcome Trust Research Programme laboratory’s COVID-19 response [version 2; peer revi... by Shadrack Mutua, Brian Bartilol, Debra Riako, Lydia Nyamako, Angela Karani, Daisy Mugo, Brian Tawa, Michael Opiyo, Wesley Cheruiyot, Metrine Tendwa, Oscar Kai, Caroline Ngetsa, Yiakon Sein, Nelson Ouma, Arnold W. Lambisia, Bonface M. Gichuki, Boniface Karia, John M. Morobe, Shaban Mwangi, Benjamin Tsofa, Philip Bejon, Alfred Mwakubia, Fredrick Mitsanze, Kelly Ominde, Patience Kiyuka, Martin Rono, Johnstone Makale, Agnes Mutiso, Perpetual Wanjiku, Victor Osoti, John N. Gitonga, Alfred Mwanzu, Calleb Odundo, Martin Mutunga, Salim Mwarumba, Donwilliams O. Omuoyo, Amek Nyaguara, Clement Lewa, Elijah Gicheru, Wilson Gumbi, Jennifer Musyoki, Susan Njuguna, Moses Mosobo, Lynette Isabella Ochola-Oyier, Horace Gumba, Wilfred Nyamu, Khadija Said Mohammed, Janet Thoya, Edward Otieno, Domtila Kimani, Jedidah Mwacharo, David Amadi, Charles N. Agoti, Zaydah R. de Laurent, Robinson Cheruiyot

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Pf7: an open dataset of Plasmodium falciparum genome variation in 20,000 worldwide samples [version 1; peer review: 2 approved] by Mohamed Hassan Abdelraheem, Sonia Goncalves, Lemu Golassa, Tim Anderson, Desmond Omane Acheampong, Enoch Aninagyei, Ifeyinwa Aniebo, Patrick O Ansah, Felix Ansah, Gordon A Awandare, Paulo Arnaldo, Maciej F Boni, Gwladys I Bertin, Peter C Bull, Marielle Bouyou-Akotet, Keobouphaphone Chindavongsa, Edwin Kamau, Huch Cheah, Claire Kamaliddin, Vladimir Corredor, David J Conway, Nicholas Day, Abibatou Konaté, Erin Courtier, Theerarat Kochakarn, Arjen Dondorp, Abdoulaye Djimde, Diego F Echeverry, Seydou Doumbia, Mara Lawniczak, Pharath Lim, Sonia Maria Mauricio Enosse, Oumou Maïga-Ascofaré, Thomas G Egwang, Aung Myint Thu, Mark Fleharty, Jutta Marfurt, Caterina A Fanello, Mark Fukuda, Victor Mobegi, Matthew Forbes, Sara Anne Healy, G L Abby Harrison, Anastasia Hernandez-Koutoucheva, Jason A Hendry, Ivo Mueller, Francis Hombhanje, Harald Noedl, Catherine A Hill, Thuy-Nhien Nguyen, Mazza Hussein, Amanda Hott, Rintis Noviyanti, Scott A Jackson, Abraham Oduro, Deus Ishengoma, Harold Ocholla, Julia Jeans, Jean-Bosco Ouedraogo, Chris G Jacob, Drissa S Konate, Jon Keatley, Francois Nosten, Kolapo Oyebola, Myat P Kyaw, Aminatou Kone, Norbert Peshu, Samuel K Lee, Dennis Kyle, Kovana M Loua, Milijaona Randrianarivelojosia, Martha Lemnge, Sasithon Pukrittayakamee, Richard James Maude, Pascal Ringwald, Celine I Mandara, Abdelrahim Osman Mohamed, Toshihiro Mita, Jaqui Montgomery, Julian C Rayner, David Saunders, Olugbenga A Mokuolu, Lastenia Ruiz, Kathryn Murie, Peter Siba, Collins Misita Morang’a, Alex Shayo, Tuyen Nguyen Thi Kim, Thang Ngo Duc, Vincent Ntui-Njock Ntui, Colin Sutherland, Hong Nguyen Van, Xin-zhuan Su, Marie A Onyamboko, Livingstone Tavul, Irene Omedo, Richard Pearson, Antoinette Tshefu, Wellington Aghoghovwia Oyibo, Vandana Thathy, Chris Drakeley, Huynh Hong Quang, Joseph Vinetz, Christopher V Plowe, Federica Verra, Eduard Rovira-Vallbona, Jason Wendler, Anna Rosanas-Urgell, Teun Bousema, Thuy Nguyen, Mahamadou S. Sissoko, Valentin Ruano-Rubio, Alexis Nzila, Shannon Takala-Harrison, Christen Smith, William Yavo, Ngo Viet Thanh, Arthur Talman, Georgia Whitton, Mahamoudou Toure, Rob W van der Pluijm, Sarah Auburn, Antoine Claessens, Mahamadou Diakite, Kesinee Chotivanich, Mehul Dhorda, Olivo Miotto, Mallika Imwong, Mayfong Mayxay, Alfred Amambua-Ngwa, Philip Bejon, Elizabeth Ashley, Alyssa Barry, Rick M. Fairhurst, Ye Htut, Tran Tinh Hien, Kimberly J Johnson, Dominic P Kwiatkowski, Umberto D'Alessandro, Chanthap Lon, Paul N Newton, Aung P Phyo, Ric N Price, Victoria J Simpson, Kevin Marsh, Nicholas J White, Thomas E Wellems, Lynette Isabella Ochola-Oyier, Mozam Ali, Ambroise Ahouidi, Jacob Almagro-Garcia, Ben Andagalu, Lucas Amenga-Etego, Voahangy Andrianaranjaka, Tobias Apinjoh, Vito Baraka, Hampate Ba, Steffen Borrmann, Oralee Branch, Thanat Chookajorn, Souleymane Dama, Chanaki Amaratunga, Alister Craig, Brigitte Denis, Eleanor Drury, Christiane Dolecek, Patrick Duffy, Berhanu Erko, Abdul Faiz, Muzamil Mahdi Abdel Hamid, Anita Ghansah, Dionicia Gamboa

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