Toll-like receptor 7 protects from atherosclerosis by constraining "inflammatory" macrophage activation. by Salagianni, M, Galani, I, Lundberg, A, Davos, C, Varela, A, Gavriil, A, Lyytikäinen, L, Lehtimäki, T, Sigala, F, Folkersen, L, Gorgoulis, V, Lenglet, S, Montecucco, F, Mach, F, Hedin, U, Hansson, G, Monaco, C, Andreakos, E

Toll-like receptor 7 protects from atherosclerosis by constraining inflammatory macrophage activation by Salagianni, M, Galani, I, Lundberg, A, Davos, C, Varela, A, Gavriil, A, Lyytikäinen, L, Lehtimäki, T, Sigala, F, Folkersen, L, Gorgoulis, V, Lenglet, S, Montecucco, F, MacH, F, Hedin, U, Hansson, G, Monaco, C, Andreakos, E

Associations of functional alanine-glyoxylate aminotransferase 2 gene variants with atrial fibrillation and ischemic stroke by Seppälä, I, Kleber, M, Bevan, S, Lyytikäinen, L, Oksala, N, Hernesniemi, J, Mäkelä, K, Rothwell, P, Sudlow, C, Dichgans, M, Mononen, N, Vlachopoulou, E, Sinisalo, J, Delgado, G, Laaksonen, R, Koskinen, T, Scharnagl, H, Kähönen, M, Markus, H, März, W, Lehtimäki, T

Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking. by Stephens, S, Hartz, S, Hoft, N, Saccone, N, Corley, R, Hewitt, J, Hopfer, C, Breslau, N, Coon, H, Chen, X, Ducci, F, Dueker, N, Franceschini, N, Frank, J, Han, Y, Hansel, N, Jiang, C, Korhonen, T, Lind, P, Liu, J, Lyytikäinen, L, Michel, M, Shaffer, JR, Short, SE, Sun, J

Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking by Stephens, S, Hartz, S, Hoft, N, Saccone, N, Corley, R, Hewitt, J, Hopfer, C, Breslau, N, Coon, H, Chen, X, Ducci, F, Dueker, N, Franceschini, N, Frank, J, Han, Y, Hansel, N, Jiang, C, Korhonen, T, Lind, P, Liu, J, Lyytikäinen, L, Michel, M, Shaffer, JR, Short, SE, Sun, J

Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium. by Moayyeri, A, Hsu, Y, Karasik, D, Estrada, K, Xiao, S, Nielson, C, Srikanth, P, Giroux, S, Wilson, S, Zheng, H, Smith, A, Pye, SR, Leo, P, Teumer, A, Hwang, J, Ohlsson, C, McGuigan, F, Minster, R, Hayward, C, Olmos, J, Lyytikäinen, L, Lewis, JR, Swart, K, Masi, L, Oldmeadow, C

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers. by Hartz, S, Short, SE, Saccone, N, Culverhouse, R, Chen, L, Schwantes-An, T, Coon, H, Han, Y, Stephens, S, Sun, J, Chen, X, Ducci, F, Dueker, N, Franceschini, N, Frank, J, Geller, F, Gubjartsson, D, Hansel, N, Jiang, C, Keskitalo-Vuokko, K, Liu, Z, Lyytikäinen, L, Michel, M, Rawal, R, Rosenberger, A

Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes. by Yaghootkar, H, Lamina, C, Scott, R, Dastani, Z, Hivert, M, Warren, L, Stancáková, A, Buxbaum, S, Lyytikäinen, L, Henneman, P, Wu, Y, Cheung, C, Pankow, J, Jackson, A, Gustafsson, S, Zhao, J, Ballantyne, C, Xie, W, Bergman, R, Boehnke, M, el Bouazzaoui, F, Collins, F, Dunn, S, Dupuis, J, Forouhi, N

Gene-age interactions in blood pressure regulation: A large-scale investigation with the CHARGE, global BPgen, and ICBP consortia by Simino, J, Shi, G, Bis, J, Chasman, D, Ehret, G, Gu, X, Guo, X, Hwang, S, Sijbrands, E, Smith, A, Verwoert, G, Bragg-Gresham, J, Cadby, G, Chen, P, Cheng, C, Corre, T, De Boer, R, Goel, A, Johnson, T, Khor, C, Lluís-Ganella, C, Luan, J, Lyytikäinen, L, Nolte, I, Sim, X

Genome-wide association study identifies multiple loci influencing human serum metabolite levels. by Kettunen, J, Tukiainen, T, Sarin, A, Ortega-Alonso, A, Tikkanen, E, Lyytikäinen, L, Kangas, A, Soininen, P, Würtz, P, Silander, K, Dick, D, Rose, R, Savolainen, M, Viikari, J, Kähönen, M, Lehtimäki, T, Pietiläinen, K, Inouye, M, McCarthy, M, Jula, A, Eriksson, J, Raitakari, O, Salomaa, V, Kaprio, J, Järvelin, MR

Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia. by Simino, J, Shi, G, Bis, J, Chasman, D, Ehret, G, Gu, X, Guo, X, Hwang, S, Sijbrands, E, Smith, A, Verwoert, G, Bragg-Gresham, J, Cadby, G, Chen, P, Cheng, C, Corre, T, de Boer, R, Goel, A, Johnson, T, Khor, C, Lluís-Ganella, C, Luan, J, Lyytikäinen, L, Nolte, I, Sim, X

Genome-wide association study identifies multiple loci influencing human serum metabolite levels by Kettunen, J, Tukiainen, T, Sarin, A, Ortega-Alonso, A, Tikkanen, E, Lyytikäinen, L, Kangas, A, Soininen, P, Würtz, P, Silander, K, Dick, D, Rose, R, Savolainen, M, Viikari, J, Kähönen, M, Lehtimäki Terho, J, Pietil Currency Signinen, K, Inouye, M, McCarthy, M, Jula, A, Eriksson, J, Raitakari, O, Salomaa, V, Kaprio, J, J Currency Signrvelin, M

Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways by Young, WJ, Lahrouchi, N, Isaacs, A, Duong, T, Foco, L, Ahmed, F, Brody, JA, Salman, R, Noordam, R, Benjamins, J-W, Haessler, J, Lyytikäinen, L-P, Repetto, L, Concas, MP, van den Berg, ME, Weiss, S, Baldassari, AR, Bartz, TM, Cook, JP, Evans, DS, Freudling, R, Hines, O, Isaksen, JL, Lin, H, Mei, H, Moscati, A, Müller-Nurasyid, M, Nursyifa, C, Qian, Y, Richmond, A, Roselli, C, Ryan, KA, Tarazona-Santos, E, Thériault, S, van Duijvenboden, S, Warren, HR, Yao, J, Raza, D, Aeschbacher, S, Ahlberg, G, Alonso, A, Andreasen, L, Bis, JC, Boerwinkle, E, Campbell, A, Catamo, E, Cocca, M, Cutler, MJ, Darbar, D, De Grandi, A, Morris, AP, van Duijn, CM

Genetic studies of leptin concentrations implicate leptin in the regulation of early adiposity by Yaghootkar, H, Zhang, Y, Spracklen, CN, Karaderi, T, Huang, LO, Bradfield, J, Schurmann, C, Fine, RS, Preuss, MH, Kutalik, Z, Wittemans, LB, Lu, Y, Metz, S, Willems, SM, Li-Gao, R, Grarup, N, Wang, S, Molnos, S, Sandoval-Zárate, AA, Nalls, MA, Lange, LA, Haesser, J, Guo, X, Lyytikäinen, L-P, Feitosa, MF, Sitlani, CM, Venturini, C, Mahajan, A, Kacprowski, T, Wang, CA, Chasman, DI, Amin, N, Broer, L, Robertson, N, Young, KL, Allison, M, Auer, PL, Blüher, M, Borja, JB, Bork-Jensen, J, Carrasquilla, GD, Christofidou, P, Demirkan, A, Doege, CA, Garcia, ME, Graff, M, Guo, K, Hakonarson, H, Hong, J, Ida Chen, Y-D, van Duijn, CM, Et al.

Genetic determinants of serum testosterone concentrations in men. by Ohlsson, C, Wallaschofski, H, Lunetta, K, Stolk, L, Perry, JR, Koster, A, Petersen, A, Eriksson, J, Lehtimäki, T, Huhtaniemi, I, Hammond, G, Maggio, M, Coviello, A, Ferrucci, L, Heier, M, Hofman, A, Holliday, K, Jansson, J, Kähönen, M, Karasik, D, Karlsson, M, Kiel, D, Liu, Y, Ljunggren, O, Lorentzon, M, Lyytikäinen, L, Meitinger, T, Mellström, D, Melzer, D, Miljkovic, I, Nauck, M, Nilsson, M, Penninx, B, Pye, SR, Vasan, R, Reincke, M, Rivadeneira, F, Tajar, A, Teumer, A, Uitterlinden, A, Ulloor, J, Viikari, J, Völker, U, Völzke, H, Wichmann, H, Wu, T, Zhuang, W, Ziv, E, Wu, F, Raitakari, O, Eriksson, A, Bidlingmaier, M, Harris, T, Murray, A, de Jong, F, Murabito, J, Bhasin, S, Vandenput, L, Haring, R

Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits by Van Setten, J, Verweij, N, Mbarek, H, Niemeijer, MN, Trompet, S, Arking, DE, Brody, JA, Gandin, I, Grarup, N, Hall, LM, Hemerich, D, Lyytikäinen, L-P, Mei, H, Müller-Nurasyid, M, Prins, BP, Robino, A, Smith, AV, Warren, HR, Asselbergs, FW, Boomsma, DI, Caulfield, MJ, Eijgelsheim, M, Ford, I, Hansen, T, Harris, TB, Heckbert, SR, Hottenga, J-J, Iorio, A, Kors, JA, Linneberg, A, Macfarlane, PW, Meitinger, T, Nelson, CP, Raitakari, OT, Aldana, CT, Sinagra, G, Sinner, M, Soliman, EZ, Stoll, M, Uitterlinden, A, Van Duijn, CM, Waldenberger, M, Alonso, A, Gasparini, P, Gudnason, V, Jamshidi, Y, Kääb, S, Kanters, JK, Lehtimäki, T, Munroe, PB, Peters, A, Samani, NJ, Sotoodehnia, N, Ulivi, S, Wilson, JG, De Geus, EJC, Jukema, JW, Stricker, B, Van Der Harst, P, De Bakker, PIW, Isaacs, A

No association of coronary artery disease with x-chromosomal variants in comprehensive international meta-analysis by Loley, C, Alver, M, Assimes, T, Bjonnes, A, Goel, A, Gustafsson, S, Hernesniemi, J, Hopewell, J, Kanoni, S, Kleber, M, Lau, K, Lu, Y, Lyytikäinen, L, Nelson, C, Nikpay, M, Qu, L, Salfati, E, Scholz, M, Tukiainen, T, Willenborg, C, Won, H, Zeng, L, Zhang, W, Anand, S, Beutner, F, Bottinger, E, Clarke, R, Dedoussis, G, Do, R, Esko, T, Eskola, M, Farrall, M, Gauguier, D, Giedraitis, V, Granger, C, Hall, A, Hamsten, A, Hazen, S, Huang, J, Kähönen, M, Kyriakou, T, Laaksonen, R, Lind, L, Lindgren, C, Magnusson, P, Marouli, E, Mihailov, E, Morris, A, Nikus, K, Pedersen, N, Rallidis, L, Salomaa, V, Shah, S, Stewart, A, Thompson, J, Zalloua, P, Chambers, J, Collins, R, Ingelsson, E, Iribarren, C, Karhunen, P, Kooner, J, Lehtimäki, T, Loos, R, März, W, McPherson, R, Metspalu, A, Reilly, M, Ripatti, S, Sanghera, D, Thiery, J, Watkins, H, Deloukas, P, Kathiresan, S, Samani, N, Schunkert, H, Erdmann, J, König, I

Evidence of inbreeding depression on human height. by McQuillan, R, Eklund, N, Pirastu, N, Kuningas, M, McEvoy, B, Esko, T, Corre, T, Davies, G, Kaakinen, M, Lyytikäinen, L, Kristiansson, K, Havulinna, A, Gögele, M, Vitart, V, Tenesa, A, Aulchenko, Y, Hayward, C, Johansson, A, Boban, M, Ulivi, S, Robino, A, Boraska, V, Igl, W, Wild, S, Zgaga, L, Amin, N, Theodoratou, E, Polašek, O, Girotto, G, Lopez, L, Sala, C, Lahti, J, Laatikainen, T, Prokopenko, I, Kals, M, Viikari, J, Yang, J, Pouta, A, Estrada, K, Hofman, A, Freimer, N, Martin, N, Kähönen, M, Milani, L, Heliövaara, M, Vartiainen, E, Räikkönen, K, Masciullo, C, Starr, J, Hicks, A, Esposito, L, Kolčić, I, Farrington, S, Oostra, B, Zemunik, T, Campbell, H, Kirin, M, Pehlic, M, Faletra, F, Porteous, D, Pistis, G, Widén, E, Salomaa, V, Koskinen, S, Fischer, K, Lehtimäki, T, Heath, A, McCarthy, M, Rivadeneira, F, Montgomery, G, Tiemeier, H, Hartikainen, A, Madden, P, d'Adamo, P, Hastie, N, Gyllensten, U, Wright, A, van Duijn, C, Dunlop, M, Rudan, I, Gasparini, P, Pramstaller, P, Deary, I, Toniolo, D, Eriksson, J, Jula, A, Raitakari, O, Metspalu, A, Perola, M, Järvelin, MR, Uitterlinden, A, Visscher, P, Wilson, J

A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation. by Coviello, A, Haring, R, Wellons, M, Vaidya, D, Lehtimäki, T, Keildson, S, Lunetta, K, He, C, Fornage, M, Lagou, V, Mangino, M, Onland-Moret, N, Chen, B, Eriksson, J, Garcia, M, Liu, Y, Koster, A, Lohman, K, Lyytikäinen, L, Petersen, A, Prescott, J, Stolk, L, Vandenput, L, Wood, A, Zhuang, W, Ruokonen, A, Hartikainen, A, Pouta, A, Bandinelli, S, Biffar, R, Brabant, G, Cox, D, Chen, Y, Cummings, S, Ferrucci, L, Gunter, M, Hankinson, SE, Martikainen, H, Hofman, A, Homuth, G, Illig, T, Jansson, J, Johnson, A, Karasik, D, Karlsson, M, Kettunen, J, Kiel, D, Kraft, P, Liu, J, Ljunggren, Ö, Lorentzon, M, Maggio, M, Markus, MR, Mellström, D, Miljkovic, I, Mirel, D, Nelson, S, Morin Papunen, L, Peeters, P, Prokopenko, I, Raffel, L, Reincke, M, Reiner, A, Rexrode, K, Rivadeneira, F, Schwartz, S, Siscovick, D, Soranzo, N, Stöckl, D, Tworoger, S, Uitterlinden, A, Gils, v, Vasan, R, Wichmann, H, Zhai, G, Bhasin, S, Bidlingmaier, M, Chanock, S, De Vivo, I, Harris, T, Hunter, D, Kähönen, M, Liu, S, Ouyang, P, Spector, T, van der Schouw, Y, Viikari, J, Wallaschofski, H, McCarthy, M, Frayling, T, Murray, A, Franks, S, Järvelin, MR, de Jong, F, Raitakari, O, Teumer, A, Ohlsson, C, Murabito, J, Perry, JR

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels. by Jiang, X, O'Reilly, PF, Aschard, H, Hsu, Y-H, Richards, JB, Dupuis, J, Ingelsson, E, Karasik, D, Pilz, S, Berry, D, Kestenbaum, B, Zheng, J, Luan, J, Sofianopoulou, E, Streeten, EA, Albanes, D, Lutsey, PL, Yao, L, Tang, W, Econs, MJ, Wallaschofski, H, Völzke, H, Zhou, A, Power, C, McCarthy, MI, Michos, ED, Boerwinkle, E, Weinstein, SJ, Freedman, ND, Huang, W-Y, Van Schoor, NM, van der Velde, N, Groot, LCPGMD, Booth, SL, Vasan, RS, Liu, C-T, Zhou, Y, Ripatti, S, Ohlsson, C, Eriksson, JG, Shea, MK, Houston, DK, Kritchevsky, SB, Liu, Y, Lohman, KK, Ferrucci, L, Peacock, M, Gieger, C, Beekman, M, Slagboom, E, Deelen, J, Heemst, DV, Kleber, ME, März, W, de Boer, IH, Wood, AC, Rotter, JI, Rich, SS, Robinson-Cohen, C, Heijer, M, Jarvelin, M-R, Cavadino, A, Joshi, PK, Wilson, JF, Hayward, C, Lind, L, Michaëlsson, K, Trompet, S, Zillikens, MC, Uitterlinden, AG, Rivadeneira, F, Broer, L, Zgaga, L, Campbell, H, Theodoratou, E, Farrington, SM, Timofeeva, M, Dunlop, MG, Valdes, AM, Tikkanen, E, Lehtimäki, T, Lyytikäinen, L-P, Kähönen, M, Raitakari, OT, Mikkilä, V, Ikram, MA, Sattar, N, Jukema, JW, Wareham, NJ, Langenberg, C, Forouhi, NG, Gundersen, TE, Khaw, K-T, Butterworth, AS, Danesh, J, Spector, T, Wang, TJ, Hyppönen, E, Kraft, P, Kiel, DP