Toll-like receptor 7 protects from atherosclerosis by constraining "inflammatory" macrophage activation. gan Salagianni, M, Galani, I, Lundberg, A, Davos, C, Varela, A, Gavriil, A, Lyytikäinen, L, Lehtimäki, T, Sigala, F, Folkersen, L, Gorgoulis, V, Lenglet, S, Montecucco, F, Mach, F, Hedin, U, Hansson, G, Monaco, C, Andreakos, E

Toll-like receptor 7 protects from atherosclerosis by constraining inflammatory macrophage activation gan Salagianni, M, Galani, I, Lundberg, A, Davos, C, Varela, A, Gavriil, A, Lyytikäinen, L, Lehtimäki, T, Sigala, F, Folkersen, L, Gorgoulis, V, Lenglet, S, Montecucco, F, MacH, F, Hedin, U, Hansson, G, Monaco, C, Andreakos, E

Associations of functional alanine-glyoxylate aminotransferase 2 gene variants with atrial fibrillation and ischemic stroke gan Seppälä, I, Kleber, M, Bevan, S, Lyytikäinen, L, Oksala, N, Hernesniemi, J, Mäkelä, K, Rothwell, P, Sudlow, C, Dichgans, M, Mononen, N, Vlachopoulou, E, Sinisalo, J, Delgado, G, Laaksonen, R, Koskinen, T, Scharnagl, H, Kähönen, M, Markus, H, März, W, Lehtimäki, T

Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking. gan Stephens, S, Hartz, S, Hoft, N, Saccone, N, Corley, R, Hewitt, J, Hopfer, C, Breslau, N, Coon, H, Chen, X, Ducci, F, Dueker, N, Franceschini, N, Frank, J, Han, Y, Hansel, N, Jiang, C, Korhonen, T, Lind, P, Liu, J, Lyytikäinen, L, Michel, M, Shaffer, JR, Short, SE, Sun, J

Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking gan Stephens, S, Hartz, S, Hoft, N, Saccone, N, Corley, R, Hewitt, J, Hopfer, C, Breslau, N, Coon, H, Chen, X, Ducci, F, Dueker, N, Franceschini, N, Frank, J, Han, Y, Hansel, N, Jiang, C, Korhonen, T, Lind, P, Liu, J, Lyytikäinen, L, Michel, M, Shaffer, JR, Short, SE, Sun, J

Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium. gan Moayyeri, A, Hsu, Y, Karasik, D, Estrada, K, Xiao, S, Nielson, C, Srikanth, P, Giroux, S, Wilson, S, Zheng, H, Smith, A, Pye, SR, Leo, P, Teumer, A, Hwang, J, Ohlsson, C, McGuigan, F, Minster, R, Hayward, C, Olmos, J, Lyytikäinen, L, Lewis, JR, Swart, K, Masi, L, Oldmeadow, C

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers. gan Hartz, S, Short, SE, Saccone, N, Culverhouse, R, Chen, L, Schwantes-An, T, Coon, H, Han, Y, Stephens, S, Sun, J, Chen, X, Ducci, F, Dueker, N, Franceschini, N, Frank, J, Geller, F, Gubjartsson, D, Hansel, N, Jiang, C, Keskitalo-Vuokko, K, Liu, Z, Lyytikäinen, L, Michel, M, Rawal, R, Rosenberger, A

Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes. gan Yaghootkar, H, Lamina, C, Scott, R, Dastani, Z, Hivert, M, Warren, L, Stancáková, A, Buxbaum, S, Lyytikäinen, L, Henneman, P, Wu, Y, Cheung, C, Pankow, J, Jackson, A, Gustafsson, S, Zhao, J, Ballantyne, C, Xie, W, Bergman, R, Boehnke, M, el Bouazzaoui, F, Collins, F, Dunn, S, Dupuis, J, Forouhi, N

Gene-age interactions in blood pressure regulation: A large-scale investigation with the CHARGE, global BPgen, and ICBP consortia gan Simino, J, Shi, G, Bis, J, Chasman, D, Ehret, G, Gu, X, Guo, X, Hwang, S, Sijbrands, E, Smith, A, Verwoert, G, Bragg-Gresham, J, Cadby, G, Chen, P, Cheng, C, Corre, T, De Boer, R, Goel, A, Johnson, T, Khor, C, Lluís-Ganella, C, Luan, J, Lyytikäinen, L, Nolte, I, Sim, X

Genome-wide association study identifies multiple loci influencing human serum metabolite levels. gan Kettunen, J, Tukiainen, T, Sarin, A, Ortega-Alonso, A, Tikkanen, E, Lyytikäinen, L, Kangas, A, Soininen, P, Würtz, P, Silander, K, Dick, D, Rose, R, Savolainen, M, Viikari, J, Kähönen, M, Lehtimäki, T, Pietiläinen, K, Inouye, M, McCarthy, M, Jula, A, Eriksson, J, Raitakari, O, Salomaa, V, Kaprio, J, Järvelin, MR

Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia. gan Simino, J, Shi, G, Bis, J, Chasman, D, Ehret, G, Gu, X, Guo, X, Hwang, S, Sijbrands, E, Smith, A, Verwoert, G, Bragg-Gresham, J, Cadby, G, Chen, P, Cheng, C, Corre, T, de Boer, R, Goel, A, Johnson, T, Khor, C, Lluís-Ganella, C, Luan, J, Lyytikäinen, L, Nolte, I, Sim, X

Trans-ancestral genome-wide association study of longitudinal pubertal height growth and shared heritability with adult health outcomes gan Bradfield, JP, Kember, RL, Ulrich, A, Balkhiyarova, Z, Alyass, A, Aris, IM, Bell, JA, Broadaway, KA, Chen, Z, Chai, J, Davies, NM, Fernandez-Orth, D, Bustamante, M, Fore, R, Ganguli, A, Heiskala, A, Hottenga, J, Íñiguez, C, Kobes, S, Leinonen, J, Lowry, E, Lyytikainen, L, Mahajan, A, Pitkänen, N, McCarthy, MI

Genome-wide association study identifies multiple loci influencing human serum metabolite levels gan Kettunen, J, Tukiainen, T, Sarin, A, Ortega-Alonso, A, Tikkanen, E, Lyytikäinen, L, Kangas, A, Soininen, P, Würtz, P, Silander, K, Dick, D, Rose, R, Savolainen, M, Viikari, J, Kähönen, M, Lehtimäki Terho, J, Pietil Currency Signinen, K, Inouye, M, McCarthy, M, Jula, A, Eriksson, J, Raitakari, O, Salomaa, V, Kaprio, J, J Currency Signrvelin, M

Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways gan Young, WJ, Lahrouchi, N, Isaacs, A, Duong, T, Foco, L, Ahmed, F, Brody, JA, Salman, R, Noordam, R, Benjamins, J-W, Haessler, J, Lyytikäinen, L-P, Repetto, L, Concas, MP, van den Berg, ME, Weiss, S, Baldassari, AR, Bartz, TM, Cook, JP, Evans, DS, Freudling, R, Hines, O, Isaksen, JL, Lin, H, Mei, H, Moscati, A, Müller-Nurasyid, M, Nursyifa, C, Qian, Y, Richmond, A, Roselli, C, Ryan, KA, Tarazona-Santos, E, Thériault, S, van Duijvenboden, S, Warren, HR, Yao, J, Raza, D, Aeschbacher, S, Ahlberg, G, Alonso, A, Andreasen, L, Bis, JC, Boerwinkle, E, Campbell, A, Catamo, E, Cocca, M, Cutler, MJ, Darbar, D, De Grandi, A, Morris, AP, van Duijn, CM

Genetic studies of leptin concentrations implicate leptin in the regulation of early adiposity gan Yaghootkar, H, Zhang, Y, Spracklen, CN, Karaderi, T, Huang, LO, Bradfield, J, Schurmann, C, Fine, RS, Preuss, MH, Kutalik, Z, Wittemans, LB, Lu, Y, Metz, S, Willems, SM, Li-Gao, R, Grarup, N, Wang, S, Molnos, S, Sandoval-Zárate, AA, Nalls, MA, Lange, LA, Haesser, J, Guo, X, Lyytikäinen, L-P, Feitosa, MF, Sitlani, CM, Venturini, C, Mahajan, A, Kacprowski, T, Wang, CA, Chasman, DI, Amin, N, Broer, L, Robertson, N, Young, KL, Allison, M, Auer, PL, Blüher, M, Borja, JB, Bork-Jensen, J, Carrasquilla, GD, Christofidou, P, Demirkan, A, Doege, CA, Garcia, ME, Graff, M, Guo, K, Hakonarson, H, Hong, J, Ida Chen, Y-D, van Duijn, CM, Et al.

Genetic determinants of serum testosterone concentrations in men. gan Ohlsson, C, Wallaschofski, H, Lunetta, K, Stolk, L, Perry, JR, Koster, A, Petersen, A, Eriksson, J, Lehtimäki, T, Huhtaniemi, I, Hammond, G, Maggio, M, Coviello, A, Ferrucci, L, Heier, M, Hofman, A, Holliday, K, Jansson, J, Kähönen, M, Karasik, D, Karlsson, M, Kiel, D, Liu, Y, Ljunggren, O, Lorentzon, M, Lyytikäinen, L, Meitinger, T, Mellström, D, Melzer, D, Miljkovic, I, Nauck, M, Nilsson, M, Penninx, B, Pye, SR, Vasan, R, Reincke, M, Rivadeneira, F, Tajar, A, Teumer, A, Uitterlinden, A, Ulloor, J, Viikari, J, Völker, U, Völzke, H, Wichmann, H, Wu, T, Zhuang, W, Ziv, E, Wu, F, Raitakari, O, Eriksson, A, Bidlingmaier, M, Harris, T, Murray, A, de Jong, F, Murabito, J, Bhasin, S, Vandenput, L, Haring, R

Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits gan Van Setten, J, Verweij, N, Mbarek, H, Niemeijer, MN, Trompet, S, Arking, DE, Brody, JA, Gandin, I, Grarup, N, Hall, LM, Hemerich, D, Lyytikäinen, L-P, Mei, H, Müller-Nurasyid, M, Prins, BP, Robino, A, Smith, AV, Warren, HR, Asselbergs, FW, Boomsma, DI, Caulfield, MJ, Eijgelsheim, M, Ford, I, Hansen, T, Harris, TB, Heckbert, SR, Hottenga, J-J, Iorio, A, Kors, JA, Linneberg, A, Macfarlane, PW, Meitinger, T, Nelson, CP, Raitakari, OT, Aldana, CT, Sinagra, G, Sinner, M, Soliman, EZ, Stoll, M, Uitterlinden, A, Van Duijn, CM, Waldenberger, M, Alonso, A, Gasparini, P, Gudnason, V, Jamshidi, Y, Kääb, S, Kanters, JK, Lehtimäki, T, Munroe, PB, Peters, A, Samani, NJ, Sotoodehnia, N, Ulivi, S, Wilson, JG, De Geus, EJC, Jukema, JW, Stricker, B, Van Der Harst, P, De Bakker, PIW, Isaacs, A

No association of coronary artery disease with x-chromosomal variants in comprehensive international meta-analysis gan Loley, C, Alver, M, Assimes, T, Bjonnes, A, Goel, A, Gustafsson, S, Hernesniemi, J, Hopewell, J, Kanoni, S, Kleber, M, Lau, K, Lu, Y, Lyytikäinen, L, Nelson, C, Nikpay, M, Qu, L, Salfati, E, Scholz, M, Tukiainen, T, Willenborg, C, Won, H, Zeng, L, Zhang, W, Anand, S, Beutner, F, Bottinger, E, Clarke, R, Dedoussis, G, Do, R, Esko, T, Eskola, M, Farrall, M, Gauguier, D, Giedraitis, V, Granger, C, Hall, A, Hamsten, A, Hazen, S, Huang, J, Kähönen, M, Kyriakou, T, Laaksonen, R, Lind, L, Lindgren, C, Magnusson, P, Marouli, E, Mihailov, E, Morris, A, Nikus, K, Pedersen, N, Rallidis, L, Salomaa, V, Shah, S, Stewart, A, Thompson, J, Zalloua, P, Chambers, J, Collins, R, Ingelsson, E, Iribarren, C, Karhunen, P, Kooner, J, Lehtimäki, T, Loos, R, März, W, McPherson, R, Metspalu, A, Reilly, M, Ripatti, S, Sanghera, D, Thiery, J, Watkins, H, Deloukas, P, Kathiresan, S, Samani, N, Schunkert, H, Erdmann, J, König, I

Evidence of inbreeding depression on human height. gan McQuillan, R, Eklund, N, Pirastu, N, Kuningas, M, McEvoy, B, Esko, T, Corre, T, Davies, G, Kaakinen, M, Lyytikäinen, L, Kristiansson, K, Havulinna, A, Gögele, M, Vitart, V, Tenesa, A, Aulchenko, Y, Hayward, C, Johansson, A, Boban, M, Ulivi, S, Robino, A, Boraska, V, Igl, W, Wild, S, Zgaga, L, Amin, N, Theodoratou, E, Polašek, O, Girotto, G, Lopez, L, Sala, C, Lahti, J, Laatikainen, T, Prokopenko, I, Kals, M, Viikari, J, Yang, J, Pouta, A, Estrada, K, Hofman, A, Freimer, N, Martin, N, Kähönen, M, Milani, L, Heliövaara, M, Vartiainen, E, Räikkönen, K, Masciullo, C, Starr, J, Hicks, A, Esposito, L, Kolčić, I, Farrington, S, Oostra, B, Zemunik, T, Campbell, H, Kirin, M, Pehlic, M, Faletra, F, Porteous, D, Pistis, G, Widén, E, Salomaa, V, Koskinen, S, Fischer, K, Lehtimäki, T, Heath, A, McCarthy, M, Rivadeneira, F, Montgomery, G, Tiemeier, H, Hartikainen, A, Madden, P, d'Adamo, P, Hastie, N, Gyllensten, U, Wright, A, van Duijn, C, Dunlop, M, Rudan, I, Gasparini, P, Pramstaller, P, Deary, I, Toniolo, D, Eriksson, J, Jula, A, Raitakari, O, Metspalu, A, Perola, M, Järvelin, MR, Uitterlinden, A, Visscher, P, Wilson, J

A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation. gan Coviello, A, Haring, R, Wellons, M, Vaidya, D, Lehtimäki, T, Keildson, S, Lunetta, K, He, C, Fornage, M, Lagou, V, Mangino, M, Onland-Moret, N, Chen, B, Eriksson, J, Garcia, M, Liu, Y, Koster, A, Lohman, K, Lyytikäinen, L, Petersen, A, Prescott, J, Stolk, L, Vandenput, L, Wood, A, Zhuang, W, Ruokonen, A, Hartikainen, A, Pouta, A, Bandinelli, S, Biffar, R, Brabant, G, Cox, D, Chen, Y, Cummings, S, Ferrucci, L, Gunter, M, Hankinson, SE, Martikainen, H, Hofman, A, Homuth, G, Illig, T, Jansson, J, Johnson, A, Karasik, D, Karlsson, M, Kettunen, J, Kiel, D, Kraft, P, Liu, J, Ljunggren, Ö, Lorentzon, M, Maggio, M, Markus, MR, Mellström, D, Miljkovic, I, Mirel, D, Nelson, S, Morin Papunen, L, Peeters, P, Prokopenko, I, Raffel, L, Reincke, M, Reiner, A, Rexrode, K, Rivadeneira, F, Schwartz, S, Siscovick, D, Soranzo, N, Stöckl, D, Tworoger, S, Uitterlinden, A, Gils, v, Vasan, R, Wichmann, H, Zhai, G, Bhasin, S, Bidlingmaier, M, Chanock, S, De Vivo, I, Harris, T, Hunter, D, Kähönen, M, Liu, S, Ouyang, P, Spector, T, van der Schouw, Y, Viikari, J, Wallaschofski, H, McCarthy, M, Frayling, T, Murray, A, Franks, S, Järvelin, MR, de Jong, F, Raitakari, O, Teumer, A, Ohlsson, C, Murabito, J, Perry, JR