PKIS deep dive yields a chemical starting point for dark kinases and a cell active BRSK2 inhibitor by Tigist Y. Tamir, David H. Drewry, Carrow Wells, M. Ben Major, Alison D. Axtman

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PPP6C Negatively Regulates STING-Dependent Innate Immune Responses by Guoxin Ni, Zhe Ma, Jason P. Wong, Zhigang Zhang, Emily Cousins, M. Ben Major, Blossom Damania

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TRIM67 regulates exocytic mode and neuronal morphogenesis via SNAP47 by Fabio L. Urbina, Shalini Menon, Dennis Goldfarb, Reginald Edwards, M. Ben Major, Patrick Brennwald, Stephanie L. Gupton

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Hepatic palmitoyl-proteomes and acyl-protein thioesterase protein proximity networks link lipid modification and mitochondria by Sarah L. Speck, Dhaval P. Bhatt, Qiang Zhang, Sangeeta Adak, Li Yin, Guifang Dong, Chu Feng, Wei Zhang, M. Ben Major, Xiaochao Wei, Clay F. Semenkovich

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Correlation of alterations in the KEAP1/CUL3/NFE2L2 pathway with radiation failure in larynx squamous cell carcinoma by Siddharth Sheth, Douglas R. Farquhar, Travis P. Schrank, Wesley Stepp, Angela Mazul, Michele Hayward, Nicholas Lenze, Paul Little, Heejoon Jo, M. Ben Major, Bhishamjit S. Chera, Jose P. Zevallos, D. Neil Hayes

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Small molecule screen identifies pyrimethamine as an inhibitor of NRF2-driven esophageal hyperplasia by Chorlada Paiboonrungruang, Zhaohui Xiong, David Lamson, Yahui Li, Brittany Bowman, Julius Chembo, Caizhi Huang, Jianying Li, Eric W. Livingston, Jon E. Frank, Vivian Chen, Yong Li, Bernard Weissman, Hong Yuan, Kevin P. Williams, M. Ben Major, Xiaoxin Chen

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In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators. by Jennifer L Franks, Raquel C Martinez-Chacin, Xianxi Wang, Rochelle L Tiedemann, Thomas Bonacci, Rajarshi Choudhury, Derek L Bolhuis, Taylor P Enrico, Ryan D Mouery, Jeffrey S Damrauer, Feng Yan, Joseph S Harrison, M Ben Major, Katherine A Hoadley, Aussie Suzuki, Scott B Rothbart, Nicholas G Brown, Michael J Emanuele

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