P522: ABSOLUTE LYMPHOCYTE COUNT IS AN INDEPENDENT SURVIVAL PREDICTOR IN PATIENTS WITH ACUTE MYELOID LEUKEMIA TREATED WITH INTENSIVE CHEMOTHERAPY by G. Cristiano, J. Nanni, L. Zannoni, C. Sartor, S. Parisi, S. Paolini, C. Papayannidis, M. Cavo, A. Curti

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High Level of Circulating Tumour DNA at Diagnosis Correlates With Disease Spreading and Defines Multiple Myeloma Patients With Poor Prognosis by M. Martello, B. Taurisano, V. Solli, G. Mazzocchetti, A. Poletti, E. Borsi, S. Armuzzi, I. Vigliotta, E. Zamagni, M. Cavo, C. Terragna

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BoBafit: A copy number clustering tool designed to refit and recalibrate the baseline region of tumors’ profiles by G. Mazzocchetti, A. Poletti, V. Solli, E. Borsi, M. Martello, I. Vigliotta, S. Armuzzi, B. Taurisano, E. Zamagni, M. Cavo, C. Terragna

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S152: SETD2/H3K36ME3 DEFICIENCY SUSTAINS GENOMIC INSTABILITY AND ENHANCES CLONOGENIC POTENTIAL OF CHRONIC MYELOID LEUKEMIA (CML) PROGENITORS by M. Mancini, S. De Santis, C. Monaldi, S. Bruno, F. Castagnetti, G. Gugliotta, A. Iurlo, M. Cerrano, S. Galimberti, S. Balducci, F. Stagno, G. Rosti, M. Cavo, S. Soverini

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Hyper-activation of Aurora kinase a-polo-like kinase 1-FOXM1 axis promotes chronic myeloid leukemia resistance to tyrosine kinase inhibitors by M. Mancini, S. De Santis, C. Monaldi, L. Bavaro, M. Martelli, F. Castagnetti, G. Gugliotta, G. Rosti, M. A. Santucci, G. Martinelli, M. Cavo, S. Soverini

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P342: BASELINE GENE EXPRESSION ANALYSIS OF RELAPSED ACUTE B-LYMPHOBLASTIC LEUKEMIA PATIENTS TREATED WITH INOTUZUMAB OZOGAMICIN by C. Sartor, I. Vigliotta, V. Robustelli, G. Cristiano, J. Nanni, L. Zannoni, S. Parisi, S. Paolini, G. Marconi, G. Martinelli, A. Curti, M. Cavo, C. Terragna, C. Papayannidis

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Efficacy and safety of daratumumab with dexamethasone in patients with relapsed/refractory multiple myeloma and severe renal impairment: results of the phase 2 dare study by E. Terpos, A. Symeonidis, S. Delimpasi, E. Zamagni, E. Katodritou, E. Rivolti, M. Kyrtsonis, D. Fotiou, N. Kanellias, M. Migkou, M. Roussou, M. Gavriatopoulou, E. Hatjiharissi, M. Cavo, M. Dimopoulos

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Diagnostic Innovations: Advances in imaging techniques for diagnosis and follow-up of multiple myeloma by M. Talarico, S. Barbato, A. Cattabriga, I. Sacchetti, E. Manzato, R. Restuccia, S. Masci, F. Bigi, M. Puppi, M. Iezza, I. Rizzello, K. Mancuso, L. Pantani, P. Tacchetti, C. Nanni, M. Cavo, E. Zamagni

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P993: SETD2 IS A BONA FIDE TUMOR SUPPRESSOR IN SYSTEMIC MASTOCYTOSIS by M. Mancini, C. Monaldi, S. De Santis, C. Papayannidis, M. Rondoni, C. Sartor, S. Bruno, A. Curti, R. Zanotti, M. Bonifacio, L. Scaffidi, L. Pagano, M. Criscuolo, F. Ciceri, C. Elena, P. Tosi, P. Valent, M. Cavo, S. Soverini

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S174: HIGH LEVEL OF CIRCULATING TUMOUR DNA AT DIAGNOSIS CORRELATES WITH DISEASE SPREADING AND DEFINES MULTIPLE MYELOMA PATIENTS WITH POOR PROGNOSIS by M. Martello, A. Poletti, D. Bezzi, E. Borsi, B. Taurisano, V. Solli, S. Armuzzi, I. Vigliotta, G. Mazzocchetti, I. Pistis, L. Pantani, S. Rocchi, K. Mancuso, P. Tacchetti, I. Rizzello, M. Cavo, E. Zamagni, C. Nanni, C. Terragna

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PB2035: CAMMA 3: A MULTICENTER PHASE IB TRIAL EVALUATING THE SAFETY, PHARMACOKINETICS, AND ACTIVITY OF SUBCUTANEOUS CEVOSTAMAB MONOTHERAPY IN PATIENTS WITH RELAPSED OR REFRACTORY M... by S. Delimpasi, H. Quach, M. Cavo, P. J. Ho, C. H.-S. Lee, A. Santoro, R. Schots, P. Vlummens, D. H. Yoon, S.-S. Yoon, C. D. Santos, D. Samineni, J. Huang, K. Wehrman, U. Patil, S. Sheikh, M. A. Dimopoulos

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S184: EVALUATING TECLISTAMAB IN PATIENTS WITH RELAPSED/ REFRACTORY MULTIPLE MYELOMA FOLLOWING EXPOSURE TO OTHER B-CELL MATURATION ANTIGEN (BCMA)-TARGETED AGENTS by C. Touzeau, A. Krishnan, P. Moreau, A. Perrot, S. Z. Usmani, S. Manier, M. Cavo, C. Martinez-Chamorro, A. Nooka, T. Martin, L. Karlin, X. Leleu, N. Bahlis, B. Besemer, L. Pei, R. Verona, S. Girgis, C. Uhlar, R. Kobos, A. Garfall

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P39 DEDALO: PHASE II STUDY OF DARATUMUMAB PLUS POMALIDOMIDE AND DEXAMETHASONE (DPD) IN PATIENTS WITH RELAPSED/REFRACTORY MULTIPLE MYELOMA AND 17P DELETION by V. Montefusco, A.M. Cafro, G. Margiotta Casaluci, F. Patriarca, R. Mina, M. D’Agostino, A. Capra, C. Priola, B. Dalla Palma, R. Rizzi, A. Genua, M.T. Petrucci, L. Paris, A. Belotti, M. Cavo, C. Conticello, C. Carlo-Stella, M Boccadoro

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P36 BELANTAMAB MAFODOTIN IN PATIENTS WITH RELAPSED AND REFRACTORY MULTIPLE MYELOMA WHO HAVE RECEIVED AT LEAST ONE PROTEASOME INHIBITOR, ONE IMMUNOMODULATORY AGENT AND ONE ANTI-CD38... by M. Offidani, S. Morè, M. Cavo, D. Derudas, F. Di Raimondo, A. Cuneo, L. Baldini, R. Della Pepa, M. Musso, M. Boccadoro, P. Musto, A. Belotti, F. Fioritoni, N. Di Renzo, A. Mele, B. Gamberi, L. De Paoli, R. Zambello, S. Grammatico, M. Brociner, F. Fazio, M. T. Petrucci

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P932: ON-DEMAND PLERIXAFOR WITH CYCLOPHOSPHAMIDE AND G-CSF FOR HEMATOPOIETIC STEM-CELL MOBILIZATION IN MULTIPLE MYELOMA PATIENTS: FINAL RESULTS OF THE MOZOBL06877 STUDY by R. Mina, F. Bonello, F. Fazio, R. Saccardi, V. Bongarzoni, F. Marchesi, G. Bertuglia, P. Curci, R. M. Lemoli, S. Ballanti, T. Dentamaro, G. Benevolo, A. Capra, R. Floris, P. Tosi, A. Olivieri, D. Rota-Scalabrini, C. Cangialosi, M. Cavo, P. Corradini, G. Milone, M. Boccadoro, A. Larocca

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B08 IDECABTAGENE VICLEUCEL VERSUS STANDARD REGIMENS IN PATIENTS WITH TRIPLE-CLASS–EXPOSED RELAPSED AND REFRACTORY MULTIPLE MYELOMA: KARMMA-3 A PHASE 3 RANDOMIZED CONTROLLED TRIAL... by P. Rodríguez-Otero, S. Ailawadhi, B. Arnulf, K. Patel, M. Cavo, A.K. Nooka, S. Manier, N. Callander, L.J. Costa, R. Vij, N.J. Bahlis, P. Moreau, S.R. Solomon, M. Delforge, J. Berdeja, A. Truppel-Hartmann, Z. Yang, L. Favre-Kontula, F. Wu, J. Piasecki, M. Cook, S. Giralt

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Clinical Presentation and Long‐Term Survival Outcomes of Patients With Monoclonal Gammopathy of Renal Significance (MGRS): A Multicenter Retrospective Study by K. Mancuso, R. Mina, S. Rocchi, E. Antonioli, M. T. Petrucci, F. Fazio, A. Gozzetti, M. Salvini, C. S. Cartia, G. Bertuglia, F. Patriarca, A. B. Dalla Palma, S. Barbato, G. De Cicco, F. Bigi, E. Favero, P. Tacchetti, L. Pantani, I. Rizzello, M. Puppi, M. Talarico, V. Solli, A. Kanapari, M. Cavo, E. Zamagni

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P14: DREAMM-9: PHASE I STUDY OF BELANTAMAB MAFODOTIN PLUS STANDARD OF CARE IN PATIENTS WITH TRANSPLANT-INELIGIBLE NEWLY DIAGNOSED MULTIPLE MYELOMA by S Usmani, A Alonso, H Quach, Y Koh, A Guenther, CK Min, X Leleu, AO Abdallah, A Oriol, B Bessemer, M Garg, I Sandhu, K Weisel, E Ocio San Miguel, M Cavo, X Zhou, M Kaisermann, L Mis, D Williams, A Yeakey, G Ferron-Brady, D Figueroa, B Kremer, I Gupta, W Janowski

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B03 CARFILZOMIB AND LENALIDOMIDE FOR PRIMARY PLASMA CELL LEUKEMIA: FINAL RESULTS OF THE PROSPECTIVE PHASE 2 EMN12/HOVON-129 STUDY FOR PATIENTS AGED ≥66 YEARS by P. Musto, M.C. Minnema, W.W.H. Roeloffzen, A. Capra, B. van der Holt, A. Juul Vangsted, A. Broyl, F. Schjesvold, T. Lund, T. Silkjaer, R. Benjamin, M. Grasso, K. Lung Wu, J. Caers, M. Cavo, R. Hájek, B. Bruno, A. Gadisseur, G. Pietrantuono, M. Offidani, L. Pour, P. Sonneveld, M. Boccadoro, N. van de Donk

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P07 BORTEZOMIB-MELPHALAN-PREDNISONE (VMP) VS. LENALIDOMIDE-DEXAMETHASONE (RD) IN REAL-LIFE MULTIPLE MYELOMA PATIENTS INELIGIBLE FOR TRANSPLANT: UPDATED ANALYSIS OF THE RANDOMIZED P... by A. Larocca, M. D’Agostino, N. Giuliani, E. Antonioli, R. Zambello, S. Ronconi, I. D. Vincelli, F. Ciceri, A. P. Falcone, M. Michieli, F. Cattel, A. Capra, M. Grasso, A. M. Cafro, F. Bonello, R. Floris, M. Offidani, E. Sciorsi, G. Pietrantuono, P. Curci, F. Patriarca, M. Cavo, S. Mangiacavalli, G. Benevolo, A. Evangelista, G. Ciccone, M. Boccadoro, B. Bruno, S. Bringhen

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