M. Madan Babu

M. Madan Babu speaking at the [[Intelligent Systems for Molecular Biology]] (ISMB) conference in Chicago in 2018 M. Madan Babu is an Indian-American computational biologist and bioinformatician. He is the endowed chair in biological data science and director of the center of excellence for data-driven discovery at St. Jude Children's Research Hospital. Previously, he served as a programme leader at the MRC Laboratory of Molecular Biology (LMB). Provided by Wikipedia
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  1. 1
    From prioritisation to understanding: mechanistic predictions of variant effects

    From prioritisation to understanding: mechanistic predictions of variant effects by Greg Slodkowicz, M Madan Babu

    Published 2018-12-01
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  2. 2
    Cellular Strategies for Regulating Functional and Nonfunctional Protein Aggregation

    Cellular Strategies for Regulating Functional and Nonfunctional Protein Aggregation by Jörg Gsponer, M. Madan Babu

    Published 2012-11-01
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  3. 3
    Enabling next generation systems biology: a conversation with M. Madan Babu

    Enabling next generation systems biology: a conversation with M. Madan Babu by Thomas Lemberger, M Madan Babu

    Published 2019-12-01
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  4. 4
    Use of Host-like Peptide Motifs in Viral Proteins Is a Prevalent Strategy in Host-Virus Interactions

    Use of Host-like Peptide Motifs in Viral Proteins Is a Prevalent Strategy in Host-Virus Interactions by Tzachi Hagai, Ariel Azia, M. Madan Babu, Raul Andino

    Published 2014-06-01
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  5. 5
    Molecular determinants underlying functional innovations of TBP and their impact on transcription initiation

    Molecular determinants underlying functional innovations of TBP and their impact on transcription initiation by Charles N. J. Ravarani, Tilman Flock, Sreenivas Chavali, Madhanagopal Anandapadamanaban, M. Madan Babu, Santhanam Balaji

    Published 2020-05-01
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  6. 6
    Affinity and competition for TBP are molecular determinants of gene expression noise

    Affinity and competition for TBP are molecular determinants of gene expression noise by Charles N. J. Ravarani, Guilhem Chalancon, Michal Breker, Natalia Sanchez de Groot, M. Madan Babu

    Published 2016-02-01
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  7. 7
    Whole genome sequencing highlights genetic changes associated with laboratory domestication of C. elegans.

    Whole genome sequencing highlights genetic changes associated with laboratory domestication of C. elegans. by Katherine P Weber, Subhajyoti De, Iwanka Kozarewa, Daniel J Turner, M Madan Babu, Mario de Bono

    Published 2010-11-01
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  8. 8
    The fitness cost and benefit of phase‐separated protein deposits

    The fitness cost and benefit of phase‐separated protein deposits by Natalia Sanchez de Groot, Marc Torrent Burgas, Charles NJ Ravarani, Ala Trusina, Salvador Ventura, M Madan Babu

    Published 2019-04-01
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  9. 9
    High‐throughput discovery of functional disordered regions: investigation of transactivation domains

    High‐throughput discovery of functional disordered regions: investigation of transactivation domains by Charles NJ Ravarani, Tamara Y Erkina, Greet De Baets, Daniel C Dudman, Alexandre M Erkine, M Madan Babu

    Published 2018-05-01
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  10. 10
    Genomic analysis reveals a tight link between transcription factor dynamics and regulatory network architecture

    Genomic analysis reveals a tight link between transcription factor dynamics and regulatory network architecture by Raja Jothi, S Balaji, Arthur Wuster, Joshua A Grochow, Jörg Gsponer, Teresa M Przytycka, L Aravind, M Madan Babu

    Published 2009-08-01
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  11. 11
    Intrinsically Disordered Segments Affect Protein Half-Life in the Cell and during Evolution

    Intrinsically Disordered Segments Affect Protein Half-Life in the Cell and during Evolution by Robin van der Lee, Benjamin Lang, Kai Kruse, Jörg Gsponer, Natalia Sánchez de Groot, Martijn A. Huynen, Andreas Matouschek, Monika Fuxreiter, M. Madan Babu

    Published 2014-09-01
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  12. 12
    Molecular Deconvolution Platform to Establish Disease Mechanisms by Surveying GPCR Signaling

    Molecular Deconvolution Platform to Establish Disease Mechanisms by Surveying GPCR Signaling by Ikuo Masuho, Sreenivas Chavali, Brian S. Muntean, Nickolas K. Skamangas, Kristina Simonyan, Dipak N. Patil, Grant M. Kramer, Laurie Ozelius, M. Madan Babu, Kirill A. Martemyanov

    Published 2018-07-01
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  13. 13
    Single‐cell biology: what does the future hold?

    Single‐cell biology: what does the future hold? by Maria Polychronidou, Jingyi Hou, M Madan Babu, Prisca Liberali, Ido Amit, Bart Deplancke, Galit Lahav, Shalev Itzkovitz, Matthias Mann, Julio Saez‐Rodriguez, Fabian Theis, Roland Eils

    Published 2023-06-01
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  14. 14
    Dynamic spatiotemporal determinants modulate GPCR:G protein coupling selectivity and promiscuity

    Dynamic spatiotemporal determinants modulate GPCR:G protein coupling selectivity and promiscuity by Manbir Sandhu, Aaron Cho, Ning Ma, Elizaveta Mukhaleva, Yoon Namkung, Sangbae Lee, Soumadwip Ghosh, John H. Lee, David E. Gloriam, Stéphane A. Laporte, M. Madan Babu, Nagarajan Vaidehi

    Published 2022-12-01
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  15. 15
    Cross‐species chemogenomic profiling reveals evolutionarily conserved drug mode of action

    Cross‐species chemogenomic profiling reveals evolutionarily conserved drug mode of action by Laura Kapitzky, Pedro Beltrao, Theresa J Berens, Nadine Gassner, Chunshui Zhou, Arthur Wüster, Julie Wu, M Madan Babu, Stephen J Elledge, David Toczyski, R Scott Lokey, Nevan J Krogan

    Published 2010-12-01
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  16. 16
    Structural and functional characterization of G protein–coupled receptors with deep mutational scanning

    Structural and functional characterization of G protein–coupled receptors with deep mutational scanning by Eric M Jones, Nathan B Lubock, AJ Venkatakrishnan, Jeffrey Wang, Alex M Tseng, Joseph M Paggi, Naomi R Latorraca, Daniel Cancilla, Megan Satyadi, Jessica E Davis, M Madan Babu, Ron O Dror, Sriram Kosuri

    Published 2020-10-01
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  17. 17
    Common activation mechanism of class A GPCRs

    Common activation mechanism of class A GPCRs by Qingtong Zhou, Dehua Yang, Meng Wu, Yu Guo, Wanjing Guo, Li Zhong, Xiaoqing Cai, Antao Dai, Wonjo Jang, Eugene I Shakhnovich, Zhi-Jie Liu, Raymond C Stevens, Nevin A Lambert, M Madan Babu, Ming-Wei Wang, Suwen Zhao

    Published 2019-12-01
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  18. 18
    A conserved molecular switch in Class F receptors regulates receptor activation and pathway selection

    A conserved molecular switch in Class F receptors regulates receptor activation and pathway selection by Shane C. Wright, Paweł Kozielewicz, Maria Kowalski-Jahn, Julian Petersen, Carl-Fredrik Bowin, Greg Slodkowicz, Maria Marti-Solano, David Rodríguez, Belma Hot, Najeah Okashah, Katerina Strakova, Jana Valnohova, M. Madan Babu, Nevin A. Lambert, Jens Carlsson, Gunnar Schulte

    Published 2019-02-01
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  19. 19
    Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation

    Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation by Bas Brouwers, Edson Mendes de Oliveira, Maria Marti-Solano, Fabiola B.F. Monteiro, Suli-Anne Laurin, Julia M. Keogh, Elana Henning, Rebecca Bounds, Carole A. Daly, Shane Houston, Vikram Ayinampudi, Natalia Wasiluk, David Clarke, Bianca Plouffe, Michel Bouvier, M. Madan Babu, I. Sadaf Farooqi, Jacek Mokrosiński

    Published 2021-03-01
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  20. 20
    Defining the condensate landscape of fusion oncoproteins

    Defining the condensate landscape of fusion oncoproteins by Swarnendu Tripathi, Hazheen K. Shirnekhi, Scott D. Gorman, Bappaditya Chandra, David W. Baggett, Cheon-Gil Park, Ramiz Somjee, Benjamin Lang, Seyed Mohammad Hadi Hosseini, Brittany J. Pioso, Yongsheng Li, Ilaria Iacobucci, Qingsong Gao, Michael N. Edmonson, Stephen V. Rice, Xin Zhou, John Bollinger, Diana M. Mitrea, Michael R. White, Daniel J. McGrail, Daniel F. Jarosz, S. Stephen Yi, M. Madan Babu, Charles G. Mullighan, Jinghui Zhang, Nidhi Sahni, Richard W. Kriwacki

    Published 2023-09-01
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