Targeting KRAS mutations in pancreatic cancer: opportunities for future strategies by Anna Linehan, Mary O’Reilly, Ray McDermott, Grainne M. O’Kane, Grainne M. O’Kane

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Conservative management of intravesical erosion of a synthetic mid-urethral sling for the treatment of stress urinary incontinence, based on patient preference: A case report by M. O'Kane, G. Araklitis, A. Rantell, D. Robinson, L. Cardozo

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Order of FIB updates seldom matters: Fast reroute and fast convergence with interface‐specific forwarding by Phani Krishna Penumarthi, Aaron Pecora, Sanjib Sur, Jason M. O’Kane, Srihari Nelakuditi

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Third-Generation Tyrosine Kinase Inhibitors Targeting Epidermal Growth Factor Receptor Mutations in Non-Small Cell Lung Cancer by Tristan A. Barnes, Grainne M. O’Kane, Mark David Vincent, Natasha B. Leighl

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Erratum to: Keratinocyte growth factor in acute lung injury to reduce pulmonary dysfunction – a randomised placebo-controlled trial (KARE): study protocol by Laurence J. M. Cross, Cecilia M. O’Kane, Cliona McDowell, Jospeh J. Elborn, Michael A. Matthay, Daniel F. McAuley

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Medication Adherence Reminder System for Virtual Home Assistants: Mixed Methods Evaluation Study by Cynthia F Corbett, Elizabeth M Combs, Peyton S Chandarana, Isabel Stringfellow, Karen Worthy, Thien Nguyen, Pamela J Wright, Jason M O'Kane

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Correction: Medication Adherence Reminder System for Virtual Home Assistants: Mixed Methods Evaluation Study by Cynthia F Corbett, Elizabeth M Combs, Peyton S Chandarana, Isabel Stringfellow, Karen Worthy, Thien Nguyen, Pamela J Wright, Jason M O'Kane

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A Porcine <italic toggle="yes">Ex Vivo</italic> Lung Perfusion Model To Investigate Bacterial Pathogenesis by Amy Dumigan, Marianne Fitzgerald, Joana Sá-Pessoa Graca Santos, Umar Hamid, Cecilia M. O’Kane, Danny F. McAuley, Jose A. Bengoechea

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Simvastatin for patients with acute respiratory distress syndrome: long-term outcomes and cost-effectiveness from a randomised controlled trial by A. Agus, C. Hulme, R. M. Verghis, C. McDowell, C. Jackson, C. M. O’Kane, J. G. Laffey, D. F. McAuley

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Baseline plasma IL-18 may predict simvastatin treatment response in patients with ARDS: a secondary analysis of the HARP-2 randomised clinical trial by Andrew James Boyle, Peter Ferris, Ian Bradbury, John Conlon, Manu Shankar-Hari, Angela J. Rogers, Cecilia M. O’Kane, Daniel F. McAuley

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The value of GATA6 immunohistochemistry and computer-assisted diagnosis to predict clinical outcome in advanced pancreatic cancer by Kai Duan, Gun-Ho Jang, Robert C. Grant, Julie M. Wilson, Faiyaz Notta, Grainne M. O’Kane, Jennifer J. Knox, Steven Gallinger, Sandra Fischer

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Prebiotic Driven Increases in IL-17A Do Not Prevent Campylobacter jejuni Colonization of Chickens by Geraldine M. Flaujac Lafontaine, Philip J. Richards, Phillippa L. Connerton, Peter M. O’Kane, Nacheervan M. Ghaffar, Nicola J. Cummings, Neville M. Fish, Ian F. Connerton

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The effect of the timing of exposure to Campylobacter jejuni on the gut microbiome and inflammatory responses of broiler chickens by Phillippa L. Connerton, Philip J. Richards, Geraldine M. Lafontaine, Peter M. O’Kane, Nacheervan Ghaffar, Nicola J. Cummings, Darren L. Smith, Neville M. Fish, Ian F. Connerton

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Effect of total cholesterol and statin therapy on mortality in ARDS patients: a secondary analysis of the SAILS and HARP-2 trials by Shaun M. Pienkos, Andrew R. Moore, Jiazhen Guan, Joseph E. Levitt, Michael A. Matthay, Rebecca M. Baron, John Conlon, Daniel F. McAuley, Cecilia M. O’Kane, Angela J. Rogers

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Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis of the LUNG SAFE database by Andrew J. Boyle, Fabiana Madotto, John G. Laffey, Giacomo Bellani, Tài Pham, Antonio Pesenti, B. Taylor Thompson, Cecilia M. O’Kane, Adam M. Deane, Daniel F. McAuley, on behalf of the LUNG SAFE Investigators, the ESICM Trials Group

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Clinically impactful metabolic subtypes of pancreatic ductal adenocarcinoma (PDAC) by Jannat Pervin, Mohammad Asad, Shaolong Cao, Gun Ho Jang, Nikta Feizi, Benjamin Haibe-Kains, Joanna M. Karasinska, Grainne M. O’Kane, Steven Gallinger, David F. Schaeffer, Daniel J. Renouf, George Zogopoulos, Oliver F. Bathe, Oliver F. Bathe

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Simvastatin to reduce pulmonary dysfunction in patients with acute respiratory distress syndrome: the HARP-2 RCT by Daniel F McAuley, John G Laffey, Cecilia M O’Kane, Gavin D Perkins, Brian Mullan, Thomas J Trinder, Paul Johnston, Phillip A Hopkins, Andrew J Johnston, Lynn Murphy, Christine McNally, Ashley M Agus, Clíona McDowell, Colette Jackson

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Defining phenotypes and treatment effect heterogeneity to inform acute respiratory distress syndrome and sepsis trials: secondary analyses of three RCTs by Manu Shankar-Hari, Shalini Santhakumaran, A Toby Prevost, Josie K Ward, Timothy Marshall, Claire Bradley, Carolyn S Calfee, Kevin L Delucchi, Pratik Sinha, Michael A Matthay, Jonathan Hackett, Cliona McDowell, John G Laffey, Anthony Gordon, Cecilia M O’Kane, Daniel F McAuley

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Chemokine expression predicts T cell-inflammation and improved survival with checkpoint inhibition across solid cancers by Joan Miguel Romero, Emma Titmuss, Yifan Wang, James Vafiadis, Alain Pacis, Gun Ho Jang, Amy Zhang, Bryn Golesworthy, Tatiana Lenko, Laura M. Williamson, Barbara Grünwald, Grainne M. O’Kane, Steven J. M. Jones, Marco. A. Marra, Julie M. Wilson, Steven Gallinger, Janessa Laskin, George Zogopoulos

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Real‐world health utility scores and toxicities to tyrosine kinase inhibitors in epidermal growth factor receptor mutated advanced non‐small cell lung cancer by Shirley Xue Jiang, Ryan N. Walton, Katrina Hueniken, Justine Baek, Alexandra McCartney, Catherine Labbé, Elliot Smith, Sze Wah Samuel Chan, RuiQi Chen, Catherine Brown, Devalben Patel, Mindy Liang, Lawson Eng, Adrian Sacher, Penelope Bradbury, Natasha B. Leighl, Frances A. Shepherd, Wei Xu, Geoffrey Liu, Manjusha Hurry, Grainne M. O'Kane

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