Resource use, costs, and approval times for planning and preparing a randomized clinical trial before and after the implementation of the new Swiss human research legislation by Speich, B, Schur, N, Gryaznov, D, Von Niederhäusern, B, Hemkens, L, Schandelmaier, S, Amstutz, A, Kasenda, B, Pauli-Magnus, C, Ojeda-Ruiz, E, Tomonaga, Y, McCord, K, Nordmann, A, Von Elm, E, Briel, M, Schwenkglenks, M, MARTA Study Group, ASPIRE Study Group