How to Transform an Exceptional Case Report Into a Therapy: Following the Frog Out of the Box by Maël Heiblig, Vincent Alcazer, Adriana Plesa, Hélène Labussière-Wallet, Pierre Sujobert

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P1135: EFFECT OF GLUCARPIDASE RESCUE IN PATIENTS WITH HIGH-DOSE METHOTREXATE INDUCED ACUTE KIDNEY INJURY: A FRENCH PHARMACOVIGILANCE DATABASE STUDY by Sabrina Pierre, Maël Heiblig, Mikaïl Nourredine, Guillaume Grenet, Kevin Bihan, Thierry Vial

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Quantitative Assessment of Vacuolization of Myeloid Precursors in VEXAS Syndrome by Audrey Rabut, Ludivine Jasserand, Camille Richard, Cecile Dumas, Fanélie Mestrallet, Estelle Bourbon, Mathieu Gerfaud Valentin, Maël Heiblig, Marion Eveillard, Yvan Jamilloux, Pierre Sujobert

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TREATMENT WITH LOW-DOSE CYTARABINE IN ELDERLY PATIENTS (AGE 70 YEARS OR OLDER) WITH ACUTE MYELOID LEUKEMIA: A SINGLE INSTITUTION EXPERIENCE by Maël Heiblig, Mohamed Elhamri, Isabelle Tigaud, Adriana Plesa, Fiorenza Barraco, Hélène Labussière, Sophie Ducastelle, Mauricette Michallet, Franck Nicolini, Claudiu Plesa, Eric Wattel, Gilles Salles, Xavier Thomas

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Recurrent Mutations of the Active Adenylation Domain of UBA1 in Atypical Form of VEXAS Syndrome by Alyx Faurel, Maël Heiblig, Olivier Kosmider, Jérôme Cornillon, Laurence Boudou, Denis Guyotat, Jean-Alain Martignoles, Yvan Jamilloux, Pauline Noyel, Elisabeth Daguenet, Anne-Camille Faure, Pierre Sujobert, Pascale Flandrin-Gresta

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Diagnosis of acute promyelocytic leukemia based on routine biological parameters using machine learning by Estelle Cheli, Simon Chevalier, Olivier Kosmider, Marion Eveillard, Nicolas Chapuis, Adriana Plesa, Maël Heiblig, Lydie Andre, Jenny Pouget, Pascal Mossuz, Olivier Theisen, Vincent Alcazer, Dan Gugenheim, Nicolas Autexier, Pierre Sujobert

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Performances of Targeted RNA Sequencing for the Analysis of Fusion Transcripts, Gene Mutation, and Expression in Hematological Malignancies by Sandrine Hayette, Béatrice Grange, Maxime Vallee, Claire Bardel, Sarah Huet, Isabelle Mosnier, Kaddour Chabane, Thomas Simonet, Marie Balsat, Maël Heiblig, Isabelle Tigaud, Franck E. Nicolini, Sylvain Mareschal, Gilles Salles, Pierre Sujobert

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LYON-UNIVERSITY HOSPITAL EXPERIENCE WITH GEMTUZUMAB OZOGAMICIN THERAPY IN ACUTE MYELOID LEUKEMIA: A ‘REAL-LIFE’ STUDY by Xavier Thomas, Marica Laurino, sandrine loron, marie-virginie larcher, gaëlle fossard, mohamed elhamri, alexandre deloire, marie balsat, fiorenza barraco, hélène labussière, sophie ducastelle, myriam renault, eric wattel, maël heiblig, gilles salles

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Human myeloid differentiation by BMP4 signaling through the VDR pathway in acute myeloid leukemia by Florence Zylbersztejn, Iryna Byelinska, Sandrine Jeanpierre, Léa Barral, Kevin Geistlich, Mario Flores-Violante, Thibault Voeltzel, Etienne Paubelle, Mael Heiblig, Vincent Alcazer, Gregoire Le Meur, Gaelle Fossard, Amine Belhabri, Ivan Cruz-Moura, Olivier Hermine, Sylvain Lefort, Véronique Maguer-Satta

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Hyperhomocysteinemia and high doses of nilotinib favor cardiovascular events in chronic phase Chronic Myelogenous Leukemia patients by Gaëlle Fossard, Emilie Blond, Marie Balsat, Stéphane Morisset, Stéphane Giraudier, Martine Escoffre-Barbe, Hélène Labussière-Wallet, Maël Heiblig, Arthur Bert, Madeleine Etienne, Jocelyne Drai, Mohamad Sobh, Isabelle Redonnet-Vernhet, Jean-Christophe Lega, François-Xavier Mahon, Gabriel Etienne, Franck Emmanuel Nicolini

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Clinical outcome of therapy‐related acute myeloid leukemia patients. Real‐life experience in a University Hospital and a Cancer Center in France by Amine Belhabri, Mael Heiblig, Stephane Morisset, Liliana Vila, Clémence Santana, Emmanuelle Nicolas‐Virelizier, Sandrine Hayette, Isabelle Tigaud, Adriana Plesa, Hélène Labussiere‐Wallet, Mohamad Sobh, Anne‐Sophie Michallet, Balsat Marie, Franck‐Emmanuel Nicolini, Yann Guillermin, Fossard Gaëlle, Laure Lebras, Philippe Rey, Lucie Jauffret‐Bertholon, Marie‐Charlotte Laude, Loron Sandrine, Mauricette Michallet

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P504: UPDATED DATA FOR ZIFTOMENIB IN PATIENTS WITH NPM1-MUTATED RELAPSED OR REFRACTORY ACUTE MYELOID LEUKEMIA by Amir Fathi, Eunice Wang, Ghayas Issa, Jessica Altman, Pau Montesinos, Stéphane de Botton, Roland Walter, Kirsten Pettit, Mrinal Patnaik, Marina Kremyanskaya, Maria Baer, James M Foran, Gary Schiller, Lionel Ades, Maël Heiblig, Pierre Peterlin, Olga Salamero Garcia, Cristina Papayannidis, Kun Nie, Julie Ahsan Mackey, Marilyn Tabachri, Daniel Corum, Mollie Leoni, Stephen Dale, Harry Erba

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Characteristics and outcomes associated with CD2 and CD25 expression on bone marrow mast cells in patients with systemic mastocytosis by Julien Rossignol, Sophie Georgin-Lavialle, Danielle Canioni, Omer Beganovic, Chantal Brouzes, Olivier Fain, Maël Heiblig, Clément Gourguechon, Philippe Guilpain, Cristina Bulai-Livideanu, Stéphane Barete, Julie Agopian, Fabienne Brenet, Patrice Dubreuil, Richard Lemal, Olivier Tournilhac, Louis Terriou, David Launay, Laurence Bouillet, Catharina Chatain, Ghandi Damaj, Thomas Ballul, Celine Greco, Laura Polivka, Laurent Frenzel, Cécile Meni, Hassiba Bouktit, Dina Benabou, Clotilde Devin, Caroline Gaudy-Marqueste, Marie Gousseff, Edwige Le Mouel, Antoine Neel, Dana Ranta, Roland Jaussaud, Thierry Jo Molina, Julie Bruneau, Rose-Marie Javier, Fabien Pelletier, Florence Castelain, Frederique Retornaz, Quentin Cabrera, Patricia Zunic, Marie Pierre Gourin, Ewa Wierzbicka-Hainaut, Jean François Viallard, Christian Lavigne, Cyrille Hoarau, Isabelle Durieu, Sophie Dimicoli-Salazar, Jose Miguel Torregrosa-Diaz, Audrey Duval, Nicolas Garcelon, Jeremie Lespinasse, Angèle Soria, Yannick Chantran, Michel Arock, Christine Bodemer, Olivier Lortholary, Vahid Asnafi, Olivier Hermine, Ludovic Lhermitte

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Characterization of patients with clonal mast cells in the bone marrow with clinical significance not otherwise specifiedResearch in context by Thomas Ballul, Vito Sabato, Peter Valent, Olivier Hermine, Olivier Lortholary, Julien Rossignol, Thomas Ballul, Vito Sabato, Cristina Bulai Livideanu, Antoine Neuraz, Julie Agopian, Fabienne Brenet, Patrice Dubreuil, Didier G. Ebo, Michiel Beyens, Richard Lemal, Olivier Tournilhac, Louis Terriou, David Launay, Laurence Bouillet, Catharina Chatain, Clément Gourguechon, Gandhi Damaj, Stéphane Durupt, Celine Greco, Laurent Frenzel, Christine Bodemer-Skandalis, Laura Polivka, Marine Madrange, Cécile Meni, Hassiba Bouktit, Anne Florence Bellais, Jean-Marc Durand, Marie Gousseff, Edwige Le Mouel, Mohamed Hamidou, Antoine Neel, Dana Ranta, Mathilde Niault, Aurélie Schiffmann, Stéphane Barete, Michel Arock, Danielle Canioni, Thierry Jo Molina, Julie Bruneau, Mélanie Vaes, Violaine Havelange, Hassan Faour, Nicolas Garcelon, Rose-Marie Javier, Fabien Pelletier, Florence Castelain, Denis Vincent, Frédérique Retornaz, Quentin Cabrera, Patricia Zunic, Philippe Guilpain, Marie Pierre Gourin, Ewa Wierzbicka–Hainaut, Jean François Viallard, Christian Lavigne, Cyrille Hoarau, Ludovic Lhermitte, Maël Heiblig, Roland Jaussaud, Peter Valent, Olivier Hermine, Olivier Lortholary, Julien Rossignol

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