499 Myeloid diversity in hormone receptor positive breast cancer reveals myeloid and lymphoid signaling pathways that correlate with T cell inhibition by Jennifer L Guerriero, Madeline G Townsend, Daniel E Michaud, Kenichi Shimada, Chenyi Gu, Lukas Kania

Comparing syngeneic and autochthonous models of breast cancer to identify tumor immune components that correlate with response to immunotherapy in breast cancer by Jessica Castrillon Lal, Madeline G. Townsend, Anita K. Mehta, Madisson Oliwa, Eric Miller, Alaba Sotayo, Emily Cheney, Elizabeth A. Mittendorf, Anthony Letai, Jennifer L. Guerriero

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982 Immune mediated mechanisms of PARPi resistance in BRCA1-associated triple negative breast cancer (TNBC) by Geoffrey I Shapiro, Anita Mehta, Jennifer L Guerriero, Adam Nelson, Patrice A Lee, Madisson Oliwa, Filipa Lynce, Nabihah Tayob, Madeline G Townsend, Kelly F Zheng, Nicholas A Saccomano

1111 Targeting lipid metabolism to improve PARP inhibitor response in BRCA-associated TNBC by Geoffrey I Shapiro, Jessica Thaxton, Anita Mehta, Jennifer L Guerriero, Adam Nelson, Carlos Wagner Wanderley, Filipa Lynce, Madeline G Townsend, Kelly F Zheng, Daniel E Michaud, Kiran Kurmi, Shakchhi Joshi, Marcia Haigis

896 Characterizing macrophage heterogeneity in HR+/HER2- metastatic breast cancer reveals novel mechanisms of resistance by Sara M Tolaney, Tianyu Li, Elizabeth A Mittendorf, Sandro Santagata, Jennifer L Guerriero, Nabihah Tayob, Peter K Sorger, Madeline G Townsend, Kelly F Zheng, Kenichi Shimada, Molly DiLullo, Eileen Wrabel, Tanya Keenan, Romualdo Barroso-Sousa

885 Characterization of the tumor microenvironment in advanced breast cancer patients treated with talazoparib followed by combination of talazoparib and avelumab by Edward T Richardson, Geoffrey I Shapiro, Jennifer L Guerriero, Claudine Isaacs, Filipa Lynce, Madeline G Townsend, Kelly F Zheng, Paula R Pohlmann, Kenichi Shimada, Arielle Heeke, Xue Geng, Candace Mainor, Mei Wei, Julie M Collins, Lauren M Sloat, Jane Staunton, Stuart J Schnitt, Joan S Brugge, Hongkun Wang

Qualification of a multiplexed tissue imaging assay and detection of novel patterns of HER2 heterogeneity in breast cancer by Jennifer L. Guerriero, Jia-Ren Lin, Ricardo G. Pastorello, Ziming Du, Yu-An Chen, Madeline G. Townsend, Kenichi Shimada, Melissa E. Hughes, Siyang Ren, Nabihah Tayob, Kelly Zheng, Shaolin Mei, Alyssa Patterson, Krishan L. Taneja, Otto Metzger, Sara M. Tolaney, Nancy U. Lin, Deborah A. Dillon, Stuart J. Schnitt, Peter K. Sorger, Elizabeth A. Mittendorf, Sandro Santagata

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