Discovery of a novel and selective Indoleamine 2,3-Dioxygenase (IDO-1) inhibitor 3-(5-Fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione (EOS200271/PF-06840003) and its characterization as... by Crosignani, S, Bingham, P, Bottemanne, P, Cannelle, H, Cauwenberghs, S, Cordonnier, M, Dalvie, D, Deroose, F, Feng, JL, Gomes, B, Greasley, S, Kaiser, SE, Kraus, M, Négrerie, M, Maegley, K, Miller, N, Murray, BW, Schneider, M, Soloweij, J, Stewart, AE, Tumang, J, Torti, VR, Van Den Eynde, B, Wythes, M

Characterization of the selective indoleamine 2,3-dioxygenase-1 (IDO1) catalytic inhibitor EOS200271/PF-06840003 supports IDO1 as a critical resistance mechanism to PD-(L)1 blockad... by Gomes, B, Driessens, G, Bartlett, D, Cai, D, Cauwenberghs, S, Crosignani, S, Dalvie, D, Denies, S, Dillon, C, Fantin, V, Guo, J, Letellier, M, Li, W, Maegley, K, Marillier, R, Miller, N, Pirson, R, Rabolli, V, Ray, C, Streiner, N, Torti, V, Tsaparikos, K, Van Den Eynde, B, Wythes, M, Yao, L, Zheng, X, Tumang, J, Kraus, M