The Role of Chronic Liver Diseases in the Emergence and Recurrence of Hepatocellular Carcinoma: An Omics Perspective af Sofia Zanotti, Gina F. Boot, Mairene Coto-Llerena, Mairene Coto-Llerena, John Gallon, Gabriel F. Hess, Savas D. Soysal, Otto Kollmar, Charlotte K. Y. Ng, Charlotte K. Y. Ng, Charlotte K. Y. Ng, Salvatore Piscuoglio, Salvatore Piscuoglio

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Discovery of synthetic lethal interactions from large-scale pan-cancer perturbation screens af Sumana Srivatsa, Hesam Montazeri, Gaia Bianco, Mairene Coto-Llerena, Mattia Marinucci, Charlotte K. Y. Ng, Salvatore Piscuoglio, Niko Beerenwinkel

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Interplay between basic residues of hepatitis C virus glycoprotein E2 with viral receptors, neutralizing antibodies and lipoproteins. af George Koutsoudakis, Jakub Dragun, Sofia Pérez-Del-Pulgar, Mairene Coto-Llerena, Laura Mensa, Gonzalo Crespo, Patricia González, Miquel Navasa, Xavier Forns

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Cell culture replication of a genotype 1b hepatitis C virus isolate cloned from a patient who underwent liver transplantation. af George Koutsoudakis, Sofia Perez-del-Pulgar, Mairene Coto-Llerena, Patricia Gonzalez, Jakub Dragun, Laura Mensa, Gonzalo Crespo, Miguel Navasa, Xavier Forns

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YAP/TAZ and ATF4 drive resistance to Sorafenib in hepatocellular carcinoma by preventing ferroptosis af Ruize Gao, Ravi K R Kalathur, Mairene Coto‐Llerena, Caner Ercan, David Buechel, Song Shuang, Salvatore Piscuoglio, Michael T Dill, Fernando D Camargo, Gerhard Christofori, Fengyuan Tang

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Supervised learning based on tumor imaging and biopsy transcriptomics predicts response of hepatocellular carcinoma to transarterial chemoembolization af Tuyana Boldanova, Geoffrey Fucile, Jan Vosshenrich, Aleksei Suslov, Caner Ercan, Mairene Coto-Llerena, Luigi M. Terracciano, Christoph J. Zech, Daniel T. Boll, Stefan Wieland, Markus H. Heim

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Standardizing Patient-Derived Organoid Generation Workflow to Avoid Microbial Contamination From Colorectal Cancer Tissues af Mattia Marinucci, Caner Ercan, Caner Ercan, Stephanie Taha-Mehlitz, Stephanie Taha-Mehlitz, Lana Fourie, Federica Panebianco, Gaia Bianco, John Gallon, Sebastian Staubli, Savas D. Soysal, Andreas Zettl, Stephan Rauthe, Jürg Vosbeck, Raoul A. Droeser, Martin Bolli, Ralph Peterli, Markus von Flüe, Charlotte K. Y. Ng, Otto Kollmar, Mairene Coto-Llerena, Mairene Coto-Llerena, Salvatore Piscuoglio, Salvatore Piscuoglio

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Transposon-activated POU5F1B promotes colorectal cancer growth and metastasis af Laia Simó-Riudalbas, Sandra Offner, Evarist Planet, Julien Duc, Laurence Abrami, Sagane Dind, Alexandre Coudray, Mairene Coto-Llerena, Caner Ercan, Salvatore Piscuoglio, Claus Lindbjerg Andersen, Jesper Bertram Bramsen, Didier Trono

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Patient-derived tumor organoids for personalized medicine in a patient with rare hepatocellular carcinoma with neuroendocrine differentiation: a case report af Marie-Anne Meier, Sandro Nuciforo, Mairene Coto-Llerena, John Gallon, Matthias S. Matter, Caner Ercan, Jürg Vosbeck, Luigi M. Terracciano, Savas D. Soysal, Daniel Boll, Otto Kollmar, Raphaël Delaloye, Salvatore Piscuoglio, Markus H. Heim

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Interferon lambda 4 impairs hepatitis C viral antigen presentation and attenuates T cell responses af Qian Chen, Mairene Coto-Llerena, Aleksei Suslov, Raphael Dias Teixeira, Isabel Fofana, Sandro Nuciforo, Maike Hofmann, Robert Thimme, Nina Hensel, Volker Lohmann, Charlotte K. Y. Ng, George Rosenberger, Stefan Wieland, Markus H. Heim

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Patient-derived organoids identify tailored therapeutic options and determinants of plasticity in sarcomatoid urothelial bladder cancer af Michele Garioni, Viviane J. Tschan, Lauriane Blukacz, Sandro Nuciforo, Romuald Parmentier, Luca Roma, Mairene Coto-Llerena, Heike Pueschel, Salvatore Piscuoglio, Tatjana Vlajnic, Frank Stenner, Hans-Helge Seifert, Cyrill A. Rentsch, Lukas Bubendorf, Clémentine Le Magnen

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USP29-mediated HIF1α stabilization is associated with Sorafenib resistance of hepatocellular carcinoma cells by upregulating glycolysis af Ruize Gao, David Buechel, Ravi K. R. Kalathur, Marco F. Morini, Mairene Coto-Llerena, Caner Ercan, Salvatore Piscuoglio, Qian Chen, Tanja Blumer, Xueya Wang, Eva Dazert, Markus H. Heim, Michael N. Hall, Fengyuan Tang, Gerhard Christofori

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Hepatocellular Carcinoma Xenografts Established From Needle Biopsies Preserve the Characteristics of the Originating Tumors af Tanja Blumer, Isabel Fofana, Matthias S. Matter, Xueya Wang, Hesam Montazeri, Diego Calabrese, Mairene Coto‐Llerena, Tujana Boldanova, Sandro Nuciforo, Venkatesh Kancherla, Luigi Tornillo, Salvatore Piscuoglio, Stefan Wieland, Luigi M. Terracciano, Charlotte K.Y. Ng, Markus H. Heim

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Microbiota-induced tissue signals regulate ILC3-mediated antigen presentation af Frank Michael Lehmann, Nicole von Burg, Robert Ivanek, Claudia Teufel, Edit Horvath, Annick Peter, Gleb Turchinovich, Daniel Staehli, Tobias Eichlisberger, Mercedes Gomez de Agüero, Mairene Coto-Llerena, Michaela Prchal-Murphy, Veronika Sexl, Mohamed Bentires-Alj, Christoph Mueller, Daniela Finke

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High Expression of FAP in Colorectal Cancer Is Associated With Angiogenesis and Immunoregulation Processes af Mairene Coto-Llerena, Caner Ercan, Venkatesh Kancherla, Stephanie Taha-Mehlitz, Stephanie Taha-Mehlitz, Serenella Eppenberger-Castori, Savas D. Soysal, Charlotte K. Y. Ng, Martin Bolli, Markus von Flüe, Guillaume P. Nicolas, Luigi M. Terracciano, Melpomeni Fani, Salvatore Piscuoglio, Salvatore Piscuoglio, Salvatore Piscuoglio

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Integrative proteogenomic characterization of hepatocellular carcinoma across etiologies and stages af Charlotte K. Y. Ng, Eva Dazert, Tuyana Boldanova, Mairene Coto-Llerena, Sandro Nuciforo, Caner Ercan, Aleksei Suslov, Marie-Anne Meier, Thomas Bock, Alexander Schmidt, Sylvia Ketterer, Xueya Wang, Stefan Wieland, Matthias S. Matter, Marco Colombi, Salvatore Piscuoglio, Luigi M. Terracciano, Michael N. Hall, Markus H. Heim

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Transcriptional Enhancer Factor Domain Family member 4 Exerts an Oncogenic Role in Hepatocellular Carcinoma by Hippo‐Independent Regulation of Heat Shock Protein 70 Family Members... af Mairene Coto‐Llerena, Nadia Tosti, Stephanie Taha‐Mehlitz, Venkatesh Kancherla, Viola Paradiso, John Gallon, Gaia Bianco, Andrea Garofoli, Souvik Ghosh, Fengyuan Tang, Caner Ercan, Gerhard M. Christofori, Matthias S. Matter, Raoul A. Droeser, Mihaela Zavolan, Savas D. Soysal, Markus vonFlüe, Otto Kollmar, Luigi M. Terracciano, Charlotte K. Y. Ng, Salvatore Piscuoglio

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Epigenetic priming in chronic liver disease impacts the transcriptional and genetic landscapes of hepatocellular carcinoma af John Gallon, Mairene Coto‐Llerena, Caner Ercan, Gaia Bianco, Viola Paradiso, Sandro Nuciforo, Stephanie Taha‐Melitz, Marie‐Anne Meier, Tujana Boldanova, Sofía Pérez‐del‐Pulgar, Sergio Rodríguez‐Tajes, Markus vonFlüe, Savas D. Soysal, Otto Kollmar, Josep M. Llovet, Augusto Villanueva, Luigi M. Terracciano, Markus H. Heim, Charlotte K. Y. Ng, Salvatore Piscuoglio

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Genomic analysis of focal nodular hyperplasia with associated hepatocellular carcinoma unveils its malignant potential: a case report af Caner Ercan, Mairene Coto-Llerena, John Gallon, Lana Fourie, Mattia Marinucci, Gabriel F. Hess, Jürg Vosbeck, Stephanie Taha-Mehlitz, Tuyana Boldanova, Marie-Anne Meier, Alexandar Tzankov, Matthias S. Matter, Martin H. K. Hoffmann, Luca Di Tommaso, Markus von Flüe, Charlotte K. Y. Ng, Markus H. Heim, Savas D. Soysal, Luigi M. Terracciano, Otto Kollmar, Salvatore Piscuoglio

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TMEM123 a key player in immune surveillance of colorectal cancer af Elisa Pesce, Chiara Cordiglieri, Mauro Bombaci, Serenella Eppenberger-Castori, Stefania Oliveto, Cristina Manara, Mariacristina Crosti, Caner Ercan, Mairene Coto, Andrea Gobbini, Susanna Campagnoli, Tiziano Donnarumma, Manuele Martinelli, Valeria Bevilacqua, Elisa De Camilli, Paola Gruarin, Maria L. Sarnicola, Elisa Cassinotti, Ludovica Baldari, Giuseppe Viale, Giuseppe Viale, Stefano Biffo, Stefano Biffo, Sergio Abrignani, Sergio Abrignani, Luigi M. Terracciano, Luigi M. Terracciano, Renata Grifantini, Renata Grifantini

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