Odyssey of Patent Foramen Ovale: Closure in Cryptogenic Stroke: The Canary in the Coal Mine of Clinical Trials? by Sreekanth Vemulapalli, Manesh R. Patel

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Is Paclitaxel Causing Mortality During Lower‐Extremity Revascularization? by Rajesh V. Swaminathan, W. Schuyler Jones, Manesh R. Patel

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Incidence and characteristics of major bleeding among rivaroxaban users with renal disease and nonvalvular atrial fibrillation by Manesh R. Patel, W. Frank Peacock, Sally Tamayo, Nicholas Sicignano, Kathleen P. Hopf, Zhong Yuan

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Phenome‐Wide Association Study of Severe COVID‐19 Genetic Risk Variants by Jessica A. Regan, Jawan W. Abdulrahim, Nathan A. Bihlmeyer, Carol Haynes, Lydia Coulter Kwee, Manesh R. Patel, Svati H. Shah

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The Cardiac Effects of COVID-19 on Young Competitive Athletes: Results from the Outcomes Registry for Cardiac Conditions in Athletes (ORCCA) by Nathaniel Moulson, Bradley J. Petek, Aaron L. Baggish, Kimberly G. Harmon, Stephanie A. Kliethermes, Manesh R. Patel, Timothy W. Churchill, Jonathan A. Drezner

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Development and Integration of Machine Learning Algorithm to Identify Peripheral Arterial Disease: Multistakeholder Qualitative Study by Sabrina M Wang, H D Jeffry Hogg, Devdutta Sangvai, Manesh R Patel, E Hope Weissler, Katherine C Kellogg, William Ratliff, Suresh Balu, Mark Sendak

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Cardiac Troponin Testing as a Component of Return to Play Cardiac Screening in Young Competitive Athletes Following SARS‐CoV‐2 Infection by Nathaniel Moulson, Bradley J. Petek, Timothy W. Churchill, Jonathan A. Drezner, Kimberly G. Harmon, Stephanie A. Kliethermes, Pranav Mellacheruvu, Manesh R. Patel, Aaron L. Baggish

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Adherence to Guideline‐Recommended Therapy—Including Supervised Exercise Therapy Referral—Across Peripheral Artery Disease Specialty Clinics: Insights From the International PORTRA... by John T. Saxon, David M. Safley, Carlos Mena‐Hurtado, Jan Heyligers, Robert Fitridge, Mehdi Shishehbor, John A. Spertus, Kensey Gosch, Manesh R. Patel, Kim G. Smolderen

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Risk Factor Burden and Long‐Term Prognosis of Patients With Premature Coronary Artery Disease by Michel Zeitouni, Robert M. Clare, Karen Chiswell, Jawan Abdulrahim, Nishant Shah, Neha P. Pagidipati, Svati H. Shah, Matthew T. Roe, Manesh R. Patel, W. Schuyler Jones

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Call to action: Understanding the differences in the use of SGLT-2 inhibitors and GLP-1 receptor agonists by Apurva Khedagi, Cara Hoke, Michelle Kelsey, Andrea Coviello, W. Schuyler Jones, Larry R. Jackson, II, Manesh R Patel, Rob W. McGarrah, Neha J Pagidipati, Nishant P. Shah

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Clinical spectrum of COVID-19 complications in young adults: combined analysis of the American Heart Association COVID-19 Cardiovascular Disease Registry and the Outcomes Registry... by Stephanie A Kliethermes, Jonathan A Drezner, Aaron L Baggish, Manesh R Patel, Kimberly Harmon, Nathaniel Moulson, Timothy W Churchill, Aakash Bavishi, Bradley Petek, Pranav Mellacheruvu, Raja Kannan Mutharasan

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Understanding Study Drug Discontinuation Through EUCLID by E. Hope Weissler, Hillary Mulder, Frank W. Rockhold, Iris Baumgartner, Lars Norgren, Juuso Blomster, Brian G. Katona, F. Gerry R. Fowkes, Kenneth Mahaffey, Marc Bonaca, Manesh R. Patel, W. Schuyler Jones

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Total Cardiovascular and Limb Events and the Impact of Polyvascular Disease in Chronic Symptomatic Peripheral Artery Disease by Michael Szarek, Connie Hess, Manesh R. Patel, W. Schuyler Jones, Jeffrey S. Berger, Iris Baumgartner, Brian Katona, Kenneth W. Mahaffey, Lars Norgren, Juuso Blomster, Frank W. Rockhold, Judith Hsia, F. Gerry R. Fowkes, Marc P. Bonaca

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Sex‐Based Differences in Outcomes Following Peripheral Artery Revascularization: Insights From VOYAGER PAD by Connie N. Hess, Iris Baumgartner, Sonia S. Anand, Mark R. Nehler, Manesh R. Patel, E. Sebastian Debus, Michael Szarek, Warren Capell, Eva Muehlhofer, Scott D. Berkowitz, Lloyd P. Haskell, Rupert M. Bauersachs, Marc P. Bonaca, Judith Hsia

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Cardiovascular and Limb Events Following Endovascular Revascularization Among Patients ≥65 Years Old: An American College of Cardiology PVI Registry Analysis by E. Hope Weissler, Yongfei Wang, Jordan M. Gales, Dmitriy N. Feldman, Shipra Arya, Eric A. Secemsky, Herbert D. Aronow, Beau M. Hawkins, J. Antonio Gutierrez, Manesh R. Patel, Jeptha P. Curtis, W. Schuyler Jones, Rajesh V. Swaminathan

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Practice Pattern, Diagnostic Yield, and Long‐Term Prognostic Impact of Coronary Computed Tomographic Angiography by Min Soo Cho, Jae‐Hyung Roh, Hanbit Park, Sang‐Cheol Cho, Do‐Yoon Kang, Pil Hyung Lee, Jung‐Min Ahn, Hyun Jung Koo, Dong Hyun Yang, Joon‐Won Kang, Seung‐Jung Park, Manesh R. Patel, Duk‐Woo Park

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Termination Based on Event Accrual in Per Protocol Versus Intention to Treat in the ROCKET AF Trial by Anthony P. Carnicelli, Anne S. Hellkamp, Kenneth W. Mahaffey, Daniel E. Singer, Günter Breithardt, Jonathan L. Halperin, Graeme J. Hankey, Jonathan P. Piccini, Richard C. Becker, Christopher C. Nessel, Scott D. Berkowitz, Keith A. A. Fox, Robert M. Califf, Manesh R. Patel

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Safety and Efficacy of Rivaroxaban in Patients With Cardiac Implantable Electronic Devices: Observations From the ROCKET AF Trial by George C. Leef, Anne S. Hellkamp, Manesh R. Patel, Richard C. Becker, Scott D. Berkowitz, Günter Breithardt, Jonathan L. Halperin, Graeme J. Hankey, Werner Hacke, Christopher C. Nessel, Daniel E. Singer, Keith A.A. Fox, Kenneth W. Mahaffey, Jonathan P. Piccini

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Splanchnic Nerve Modulation Effects on Surrogate Measures of Venous Capacitance by Veraprapas Kittipibul, Arun Ganesh, Aubrie Coburn, Brian J. Coyne, James Matthew Gray, Jeroen Molinger, Neil Ray, Mihai Podgoreanu, Sharon L. McCartney, Negmeldeen Mamoun, Robert Curtis Fitzhugh, Philipp Lurz, Cynthia L. Green, Adrian F. Hernandez, Manesh R. Patel, Marat Fudim

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Selective Serotonin Reuptake Inhibitors and Bleeding Risk in Anticoagulated Patients With Atrial Fibrillation: An Analysis From the ROCKET AF Trial by Gene R. Quinn, Anne S. Hellkamp, Graeme J. Hankey, Richard C. Becker, Scott D. Berkowitz, Günter Breithardt, Maurizio Fava, Keith A. A. Fox, Jonathan L. Halperin, Kenneth W. Mahaffey, Christopher C. Nessel, Manesh R. Patel, Jonathan P. Piccini, Daniel E. Singer

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