Monocyte TREM-1 Levels Associate With Anti-TNF Responsiveness in IBD Through Autophagy and Fcγ-Receptor Signaling Pathways by Marileen M. Prins, Bram Verstockt, Bram Verstockt, Marc Ferrante, Marc Ferrante, Séverine Vermeire, Séverine Vermeire, Manon E. Wildenberg, Manon E. Wildenberg, Pim J. Koelink

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Thiopurines correct the effects of autophagy impairment on intestinal healing – a potential role for ARHGAP18/RhoA by Marileen M. C. Prins, Francesca P. Giugliano, Manon van Roest, Stan F. J. van de Graaf, Pim J. Koelink, Manon E. Wildenberg

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Colonic CD90+ Crypt Fibroblasts Secrete Semaphorins to Support Epithelial Growth by Olga N. Karpus, B. Florien Westendorp, Jacqueline L.M. Vermeulen, Sander Meisner, Jan Koster, Vanesa Muncan, Manon E. Wildenberg, Gijs R. van den Brink

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Altered Gut Structure and Anti-Bacterial Defense in Adult Mice Treated with Antibiotics during Early Life by Tnia Martins Garcia, Manon van Roest, Jacqueline L. M. Vermeulen, Sander Meisner, Jan Koster, Manon E. Wildenberg, Ruurd M. van Elburg, Vanesa Muncan, Ingrid B. Renes

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Epigenetic Signatures Discriminate Patients With Primary Sclerosing Cholangitis and Ulcerative Colitis From Patients With Ulcerative Colitis by Manon de Krijger, Manon de Krijger, Ishtu L. Hageman, Ishtu L. Hageman, Andrew Y. F. Li Yim, Jan Verhoeff, Jan Verhoeff, Juan J. Garcia Vallejo, Patricia H. P. van Hamersveld, Evgeni Levin, Evgeni Levin, Theodorus B. M. Hakvoort, Manon E. Wildenberg, Manon E. Wildenberg, Peter Henneman, Cyriel Y. Ponsioen, Wouter J. de Jonge, Wouter J. de Jonge

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T-cell responses in colorectal peritoneal metastases are recapitulated in a humanized immune system mouse model by Job Saris, Job Saris, Job Saris, Job Saris, Job Saris, Sanne Bootsma, Sanne Bootsma, Sanne Bootsma, Sanne Bootsma, Jan Verhoeff, Jan Verhoeff, Jan Verhoeff, Jan Verhoeff, Jan Verhoeff, Jan Verhoeff, Jurriaan B. Tuynman, Jurriaan B. Tuynman, Manon E. Wildenberg, Manon E. Wildenberg, Manon E. Wildenberg, Esther Siteur-van Rijnstra, Kristiaan J. Lenos, Kristiaan J. Lenos, Kristiaan J. Lenos, Kristiaan J. Lenos, Juan J. Garcia Vallejo, Juan J. Garcia Vallejo, Juan J. Garcia Vallejo, Louis Vermeulen, Louis Vermeulen, Louis Vermeulen, Louis Vermeulen, Joep Grootjans, Joep Grootjans, Joep Grootjans, Joep Grootjans, Joep Grootjans

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A practice-changing culture method relying on shaking substantially increases mitochondrial energy metabolism and functionality of human liver cell lines. by Aziza A A Adam, Vincent A van der Mark, Joanne M Donkers, Manon E Wildenberg, Ronald P J Oude Elferink, Robert A F M Chamuleau, Ruurdtje Hoekstra

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Characterization of gut-homing molecules in non-endstage livers of patients with primary sclerosing cholangitis and inflammatory bowel disease by Manon de Krijger, Thijmen Visseren, Manon E. Wildenberg, Gerrit K.J. Hooijer, Monique M.A. Verstegen, Luc J.W. van der Laan, Wouter J. de Jonge, Joanne Verheij, Cyriel Y. Ponsioen

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Berbamine suppresses intestinal SARS-CoV-2 infection via a BNIP3-dependent autophagy blockade by Alexandra P. M. Cloherty, Anusca G. Rader, Kharishma S. Patel, Jimena Pérez-Vargas, Connor A. H. Thompson, Siobhan Ennis, Masahiro Niikura, Manon E. Wildenberg, Vanesa Muncan, Renée R. C. E. Schreurs, François Jean, Carla M. S. Ribeiro

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Intestinal fibrosis is associated with lack of response to Infliximab therapy in Crohn's disease. by Jessica R de Bruyn, Marte A Becker, Jessica Steenkamer, Manon E Wildenberg, Sybren L Meijer, Christianne J Buskens, Willem A Bemelman, Mark Löwenberg, Cyriel Y Ponsioen, Gijs R van den Brink, Geert R D'Haens

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A Novel Organoid Model of Damage and Repair Identifies HNF4α as a Critical Regulator of Intestinal Epithelial RegenerationSummary by Paula S. Montenegro-Miranda, Jonathan H.M. van der Meer, Christine Jones, Sander Meisner, Jacqueline L.M. Vermeulen, Jan Koster, Manon E. Wildenberg, Jarom Heijmans, Francois Boudreau, Agnes Ribeiro, Gijs R. van den Brink, Vanesa Muncan

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Early Life Antibiotics Influence In Vivo and In Vitro Mouse Intestinal Epithelium Maturation and FunctioningSummary by Tânia Martins Garcia, Manon van Roest, Jacqueline L.M. Vermeulen, Sander Meisner, Wouter L. Smit, Joana Silva, Pim J. Koelink, Jan Koster, William J. Faller, Manon E. Wildenberg, Ruurd M. van Elburg, Vanesa Muncan, Ingrid B. Renes

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A distinct epigenetic profile distinguishes stenotic from non-inflamed fibroblasts in the ileal mucosa of Crohn's disease patients. by Andrew Y F Li Yim, Jessica R de Bruyn, Nicolette W Duijvis, Catriona Sharp, Enrico Ferrero, Wouter J de Jonge, Manon E Wildenberg, Marcel M A M Mannens, Christianne J Buskens, Geert R D'Haens, Peter Henneman, Anje A Te Velde

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ATF2 and ATF7 Are Critical Mediators of Intestinal Epithelial RepairSummary by Bartolomeus J. Meijer, Francesca P. Giugliano, Bart Baan, Jonathan H.M. van der Meer, Sander Meisner, Manon van Roest, Pim J. Koelink, Ruben J. de Boer, Nic Jones, Wolfgang Breitwieser, Nicole N. van der Wel, Manon E. Wildenberg, Gijs R. van den Brink, Jarom Heijmans, Vanesa Muncan

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Indian Hedgehog Suppresses a Stromal Cell–Driven Intestinal Immune Response by B. Florien Westendorp, Nikè V.J.A. Büller, Olga N. Karpus, Willemijn A. van Dop, Jan Koster, Rogier Versteeg, Pim J. Koelink, Clinton Y. Snel, Sander Meisner, Joris J.T.H. Roelofs, Anja Uhmann, Emiel Ver Loren van Themaat, Jarom Heijmans, Heidi Hahn, Vanesa Muncan, Manon E. Wildenberg, Gijs R. van den Brink

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FcαRI co-stimulation converts human intestinal CD103+ dendritic cells into pro-inflammatory cells through glycolytic reprogramming by Ivo S. Hansen, Lisette Krabbendam, Jochem H. Bernink, Fabricio Loayza-Puch, Willianne Hoepel, Johan A. van Burgsteden, Elsa C. Kuijper, Christianne J. Buskens, Willem A. Bemelman, Sebastiaan A. J. Zaat, Reuven Agami, Gestur Vidarsson, Gijs R. van den Brink, Esther C. de Jong, Manon E. Wildenberg, Dominique L. P. Baeten, Bart Everts, Jeroen den Dunnen

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A BET Protein Inhibitor Targeting Mononuclear Myeloid Cells Affects Specific Inflammatory Mediators and Pathways in Crohn’s Disease by Ahmed M. I. Elfiky, Ishtu L. Hageman, Marte A. J. Becker, Jan Verhoeff, Andrew Y. F. Li Yim, Vincent W. Joustra, Lieven Mulders, Ivan Fung, Inmaculada Rioja, Rab K. Prinjha, Nicholas N. Smithers, Rebecca C. Furze, Palwinder K. Mander, Matthew J. Bell, Christianne J. Buskens, Geert R. D’Haens, Manon E. Wildenberg, Wouter J. de Jonge

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Pro-inflammatory T cells-derived cytokines enhance the maturation of the human fetal intestinal epithelial barrier by Francesca P. Giugliano, Marit Navis, Sarah Ouahoud, Tânia Martins Garcia, Irini A.M. Kreulen, Evelina Ferrantelli, Sander Meisner, Jacqueline L.M. Vermeulen, Manon van Roest, Jean-Noël Billaud, Jan Koster, Yousif Dawood, Bernadette S. de Bakker, Daisy I. Picavet-Havik, Irene M. Schimmel, Nicole N. van der Wel, Pim J. Koelink, Manon E. Wildenberg, Joep P.M. Derikx, Wouter J. de Jonge, Ingrid B. Renes, Ruurd M. van Elburg, Vanesa Muncan

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