RNA Binding Proteins as Pioneer Determinants of Infection: Protective, Proviral, or Both? by Samantha Lisy, Katherine Rothamel, Manuel Ascano

Get full text

Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA by Pu Gao, Thomas Zillinger, Weiyi Wang, Manuel Ascano, Peihong Dai, Gunther Hartmann, Thomas Tuschl, Liang Deng, Winfried Barchet, Dinshaw J. Patel

Get full text

Eukaryote-Specific Insertion Elements Control Human ARGONAUTE Slicer Activity by Kotaro Nakanishi, Manuel Ascano, Tasos Gogakos, Satoko Ishibe-Murakami, Artem A. Serganov, Daniel Briskin, Pavel Morozov, Thomas Tuschl, Dinshaw J. Patel

Get full text

Pharmacological Activation of cGAS for Cancer Immunotherapy by Kyle M. Garland, Jonah C. Rosch, Carcia S. Carson, Lihong Wang-Bishop, Ann Hanna, Sema Sevimli, Casey Van Kaer, Justin M. Balko, Justin M. Balko, Manuel Ascano, John T. Wilson, John T. Wilson, John T. Wilson, John T. Wilson, John T. Wilson, John T. Wilson

Get full text

Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice by Jessica Vincent, Carolina Adura, Pu Gao, Antonio Luz, Lodoe Lama, Yasutomi Asano, Rei Okamoto, Toshihiro Imaeda, Jumpei Aida, Katherine Rothamel, Tasos Gogakos, Joshua Steinberg, Seth Reasoner, Kazuyoshi Aso, Thomas Tuschl, Dinshaw J. Patel, J. Fraser Glickman, Manuel Ascano

Get full text