Current Drug Treatment Strategies for Atrial Fibrillation and TASK-1 Inhibition as an Emerging Novel Therapy Option by Manuel Kraft, Manuel Kraft, Manuel Kraft, Antonius Büscher, Felix Wiedmann, Felix Wiedmann, Felix Wiedmann, Yannick L’hoste, Yannick L’hoste, Walter E. Haefeli, Norbert Frey, Norbert Frey, Norbert Frey, Hugo A. Katus, Hugo A. Katus, Hugo A. Katus, Constanze Schmidt, Constanze Schmidt, Constanze Schmidt

Get full text

The Experimental TASK-1 Potassium Channel Inhibitor A293 Can Be Employed for Rhythm Control of Persistent Atrial Fibrillation in a Translational Large Animal Model by Felix Wiedmann, Felix Wiedmann, Felix Wiedmann, Christoph Beyersdorf, Christoph Beyersdorf, Xiao-Bo Zhou, Xiao-Bo Zhou, Manuel Kraft, Manuel Kraft, Manuel Kraft, Kathrin I. Foerster, Ibrahim El-Battrawy, Ibrahim El-Battrawy, Siegfried Lang, Siegfried Lang, Martin Borggrefe, Martin Borggrefe, Walter E. Haefeli, Norbert Frey, Norbert Frey, Norbert Frey, Constanze Schmidt, Constanze Schmidt, Constanze Schmidt

Get full text

A porcine large animal model of radiofrequency ablation-induced left bundle branch block by Felix Wiedmann, Felix Wiedmann, Felix Wiedmann, Max Jamros, Valerie Herlt, Amelie Paasche, Amelie Paasche, Manuel Kraft, Manuel Kraft, Moritz Beck, Merten Prüser, Merten Prüser, Merten Prüser, Atilla Erkal, Maren Harder, Marcin Zaradzki, Jasmin Soethoff, Matthias Karck, Norbert Frey, Norbert Frey, Norbert Frey, Constanze Schmidt, Constanze Schmidt, Constanze Schmidt

Get full text

Simultaneous Quantification and Pharmacokinetic Characterization of Doxapram and 2-Ketodoxapram in Porcine Plasma and Brain Tissue by Manuel Kraft, Kathrin I. Foerster, Felix Wiedmann, Max Sauter, Amelie Paasche, Pablo L. Blochberger, Baran Yesilgöz, Yannick L’hoste, Norbert Frey, Walter E. Haefeli, Jürgen Burhenne, Constanze Schmidt

Get full text

Identification of the A293 (AVE1231) Binding Site in the Cardiac Two-Pore-Domain Potassium Channel TASK-1: a Common Low Affinity Antiarrhythmic Drug Binding Site by Felix Wiedmann, Aytug K. Kiper, Mauricio Bedoya, Antonius Ratte, Susanne Rinné, Manuel Kraft, Maximilian Waibel, Priya Anad, Wolfgang Wenzel, Wendy González, Hugo A. Katus, Niels Decher, Constanze Schmidt

Get full text

MicroRNAs Regulate TASK‐1 and Are Linked to Myocardial Dilatation in Atrial Fibrillation by Felix Wiedmann, Manuel Kraft, Stefan Kallenberger, Antonius Büscher, Amelie Paasche, Pablo L. Blochberger, Timon Seeger, Natasa Jávorszky, Gregor Warnecke, Rawa Arif, Jamila Kremer, Matthias Karck, Norbert Frey, Constanze Schmidt

Get full text

Pharmacologic TWIK‐Related Acid‐Sensitive K+ Channel (TASK‐1) Potassium Channel Inhibitor A293 Facilitates Acute Cardioversion of Paroxysmal Atrial Fibrillation in a Porcine Large... by Felix Wiedmann, Christoph Beyersdorf, Xiaobo Zhou, Antonius Büscher, Manuel Kraft, Jendrik Nietfeld, Teo Puig Walz, Laura A. Unger, Axel Loewe, Bastian Schmack, Arjang Ruhparwar, Matthias Karck, Dierk Thomas, Martin Borggrefe, Gunnar Seemann, Hugo A. Katus, Constanze Schmidt

Get full text