Down-regulation of acyl-CoA oxidase gene expression and increased NF-κB activity in etomoxir-induced cardiac hypertrophy by Àgatha Cabrero, Manuel Merlos, Juan C. Laguna, Manuel Vázquez Carrera

Get full text

Repeated Sigma-1 Receptor Antagonist MR309 Administration Modulates Central Neuropathic Pain Development After Spinal Cord Injury in Mice by Sílvia Castany, Xavier Codony, Daniel Zamanillo, Manuel Merlos, Enrique Verdú, Pere Boadas-Vaello

Get full text

The Sigma 2 receptor promotes and the Sigma 1 receptor inhibits mu-opioid receptor-mediated antinociception by Pilar Sánchez-Blázquez, Elsa Cortés-Montero, María Rodríguez-Muñoz, Manuel Merlos, Javier Garzón-Niño

Get full text

Evaluation of Formalin-Induced Pain Behavior and Glutamate Release in the Spinal Dorsal Horn Using In Vivo Microdialysis in Conscious Rats by Alba Vidal-Torres, Alicia Carceller, Daniel Zamanillo, Manuel Merlos, José Miguel Vela, Begoña Fernández-Pastor

Get full text

Supraspinal and Peripheral, but Not Intrathecal, σ1R Blockade by S1RA Enhances Morphine Antinociception by Alba Vidal-Torres, Begoña Fernández-Pastor, Alicia Carceller, José Miguel Vela, Manuel Merlos, Daniel Zamanillo

Get full text

Metabolic alterations and increased liver mTOR expression precede the development of autoimmune disease in a murine model of lupus erythematosus. by Laia Vilà, Núria Roglans, Miguel Baena, Emma Barroso, Marta Alegret, Manuel Merlos, Juan C Laguna

Get full text

Development of a novel in vitro assay to screen for neuroprotective drugs against iatrogenic neurite shortening. by Antón L Martínez, José Brea, Mateo Barro, Xavier Monroy, Manuel Merlos, Javier Burgueño, María Isabel Loza

Get full text

Neuroprotective Effects of Sigma 1 Receptor Ligands on Motoneuron Death after Spinal Root Injury in Mice by Núria Gaja-Capdevila, Neus Hernández, Daniel Zamanillo, Jose Miguel Vela, Manuel Merlos, Xavier Navarro, Mireia Herrando-Grabulosa

Get full text

Long-lasting reflexive and nonreflexive pain responses in two mouse models of fibromyalgia-like condition by Beltrán Álvarez-Pérez, Meritxell Deulofeu, Judit Homs, Manuel Merlos, José Miguel Vela, Enrique Verdú, Pere Boadas-Vaello

Get full text

Long-Lasting Nociplastic Pain Modulation by Repeated Administration of Sigma-1 Receptor Antagonist BD1063 in Fibromyalgia-like Mouse Models by Beltrán Álvarez-Pérez, Anna Bagó-Mas, Meritxell Deulofeu, José Miguel Vela, Manuel Merlos, Enrique Verdú, Pere Boadas-Vaello

Get full text

EST79232 and EST79376, Two Novel Sigma-1 Receptor Ligands, Exert Neuroprotection on Models of Motoneuron Degeneration by Núria Gaja-Capdevila, Neus Hernández, Sandra Yeste, Raquel F. Reinoso, Javier Burgueño, Ana Montero, Manuel Merlos, José M. Vela, Mireia Herrando-Grabulosa, Xavier Navarro

Get full text

Identification of Sodium Transients Through NaV1.5 Channels as Regulators of Differentiation in Immortalized Dorsal Root Ganglia Neurons by Antón L. Martínez, José Brea, Eduardo Domínguez, María J. Varela, Catarina Allegue, Raquel Cruz, Xavier Monroy, Manuel Merlos, Javier Burgueño, Ángel Carracedo, Ángel Carracedo, María Isabel Loza

Get full text

Bispecific sigma-1 receptor antagonism and mu-opioid receptor partial agonism: WLB-73502, an analgesic with improved efficacy and safety profile compared to strong opioids by Alba Vidal-Torres, Begoña Fernández-Pastor, Mónica García, Eva Ayet, Anna Cabot, Javier Burgueño, Xavier Monroy, Bertrand Aubel, Xavier Codony, Luz Romero, Rosalía Pascual, Maria Teresa Serafini, Gregorio Encina, Carmen Almansa, Daniel Zamanillo, Manuel Merlos, José Miguel Vela

Get full text