Epigenetics in hepatocellular carcinoma development and therapy: The tip of the icebergKey points by Maite G. Fernández-Barrena, María Arechederra, Leticia Colyn, Carmen Berasain, Matias A. Avila

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Bile as a liquid biopsy matrix: potential applications and limitations by Maria Arechederra, Maria Rullán, Daniel Oyón, Matias A. Ávila, Jesús M. Urman, Carmen Berasain

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Caspase-2 in liver disease and hepatocellular carcinoma by Amaya Lopez-Pascual, Marc Cusachs, María Arechederra, Carmen Berasain, Matías A. Ávila, Maite G. Fernández-Barrena

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Epigenetic Biomarkers for the Diagnosis and Treatment of Liver Disease by María Arechederra, Miriam Recalde, María Gárate-Rascón, Maite G. Fernández-Barrena, Matías A. Ávila, Carmen Berasain

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SLU7: A New Hub of Gene Expression Regulation—From Epigenetics to Protein Stability in Health and Disease by María Gárate-Rascón, Miriam Recalde, Carla Rojo, Maite G. Fernández-Barrena, Matías A. Ávila, María Arechederra, Carmen Berasain

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Epigenetics in Liver Fibrosis: Could HDACs be a Therapeutic Target? by Alex Claveria-Cabello, Leticia Colyn, Maria Arechederra, Jesus M. Urman, Carmen Berasain, Matias A. Avila, Maite G. Fernandez-Barrena

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Hypermethylation of gene body CpG islands predicts high dosage of functional oncogenes in liver cancer by Maria Arechederra, Fabrice Daian, Annie Yim, Sehrish K. Bazai, Sylvie Richelme, Rosanna Dono, Andrew J. Saurin, Bianca H. Habermann, Flavio Maina

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Epigenetic Mechanisms in Gastric Cancer: Potential New Therapeutic Opportunities by Matteo Canale, Andrea Casadei-Gardini, Paola Ulivi, Maria Arechederra, Carmen Berasain, Pier-Luigi Lollini, Maite G. Fernández-Barrena, Matías A. Avila

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C3G Is Upregulated in Hepatocarcinoma, Contributing to Tumor Growth and Progression and to HGF/MET Pathway Activation by Celia Sequera, Paloma Bragado, Sara Manzano, Maria Arechederra, Sylvie Richelme, Alvaro Gutiérrez-Uzquiza, Aránzazu Sánchez, Flavio Maina, Carmen Guerrero, Almudena Porras

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Prognostic value of ultra-low-pass whole-genome sequencing of circulating tumor DNA in hepatocellular carcinoma under systemic treatment by Miguel Sogbe, Idoia Bilbao, Francesco P. Marchese, Jon Zazpe, Annarosaria De Vito, Marta Pozuelo, Delia D’Avola, Mercedes Iñarrairaegui, Carmen Berasain, Maria Arechederra, Josepmaria Argemi, Bruno Sangro

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DNA Methylation Regulates a Set of Long Non-Coding RNAs Compromising Hepatic Identity during Hepatocarcinogenesis by Miriam Recalde, María Gárate-Rascón, José María Herranz, María Elizalde, María Azkona, Juan P. Unfried, Loreto Boix, María Reig, Bruno Sangro, Maite G. Fernández-Barrena, Puri Fortes, Matías A. Ávila, Carmen Berasain, María Arechederra

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Tracking Dynamics of Spontaneous Tumors in Mice Using Photon-Counting Computed Tomography by Franca Cassol, Loriane Portal, Sylvie Richelme, Mathieu Dupont, Yannick Boursier, Maria Arechederra, Nathalie Auphan-Anezin, Lionel Chasson, Caroline Laprie, Samantha Fernandez, Laure Balasse, Fabienne Lamballe, Rosanna Dono, Benjamin Guillet, Toby Lawrence, Christian Morel, Flavio Maina

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Dual Pharmacological Targeting of HDACs and PDE5 Inhibits Liver Disease Progression in a Mouse Model of Biliary Inflammation and Fibrosis by Alex Claveria-Cabello, Leticia Colyn, Iker Uriarte, Maria Ujue Latasa, Maria Arechederra, Jose M. Herranz, Laura Alvarez, Jesus M. Urman, Maria L. Martinez-Chantar, Jesus M. Banales, Bruno Sangro, Krista Rombouts, Julen Oyarzabal, Jose J. G. Marin, Carmen Berasain, Matias A. Avila, Maite G. Fernandez-Barrena

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Activation of the Unfolded Protein Response (UPR) Is Associated with Cholangiocellular Injury, Fibrosis and Carcinogenesis in an Experimental Model of Fibropolycystic Liver Disease by Chaobo Chen, Hanghang Wu, Hui Ye, Agustín Tortajada, Sandra Rodríguez-Perales, Raúl Torres-Ruiz, August Vidal, Maria Isabel Peligros, Johanna Reissing, Tony Bruns, Mohamed Ramadan Mohamed, Kang Zheng, Amaia Lujambio, Maria J. Iraburu, Leticia Colyn, Maria Ujue Latasa, María Arechederra, Maite G. Fernández-Barrena, Carmen Berasain, Javier Vaquero, Rafael Bañares, Leonard J. Nelson, Christian Trautwein, Roger J. Davis, Eduardo Martinez-Naves, Yulia A. Nevzorova, Alberto Villanueva, Matias A. Avila, Francisco Javier Cubero

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New molecular mechanisms in cholangiocarcinoma: signals triggering interleukin-6 production in tumor cells and KRAS co-opted epigenetic mediators driving metabolic reprogramming by Leticia Colyn, Gloria Alvarez-Sola, M. Ujue Latasa, Iker Uriarte, Jose M. Herranz, Maria Arechederra, George Vlachogiannis, Colin Rae, Antonio Pineda-Lucena, Andrea Casadei-Gardini, Federica Pedica, Luca Aldrighetti, Angeles López-López, Angeles López-Gonzálvez, Coral Barbas, Sergio Ciordia, Sebastiaan M. Van Liempd, Juan M. Falcón-Pérez, Jesus Urman, Bruno Sangro, Silve Vicent, Maria J. Iraburu, Felipe Prosper, Leonard J. Nelson, Jesus M. Banales, Maria Luz Martinez-Chantar, Jose J. G. Marin, Chiara Braconi, Christian Trautwein, Fernando J. Corrales, F. Javier Cubero, Carmen Berasain, Maite G. Fernandez-Barrena, Matias A. Avila

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Pilot Multi-Omic Analysis of Human Bile from Benign and Malignant Biliary Strictures: A Machine-Learning Approach by Jesús M. Urman, José M. Herranz, Iker Uriarte, María Rullán, Daniel Oyón, Belén González, Ignacio Fernandez-Urién, Juan Carrascosa, Federico Bolado, Lucía Zabalza, María Arechederra, Gloria Alvarez-Sola, Leticia Colyn, María U. Latasa, Leonor Puchades-Carrasco, Antonio Pineda-Lucena, María J. Iraburu, Marta Iruarrizaga-Lejarreta, Cristina Alonso, Bruno Sangro, Ana Purroy, Isabel Gil, Lorena Carmona, Francisco Javier Cubero, María L. Martínez-Chantar, Jesús M. Banales, Marta R. Romero, Rocio I.R. Macias, Maria J. Monte, Jose J. G. Marín, Juan J. Vila, Fernando J. Corrales, Carmen Berasain, Maite G. Fernández-Barrena, Matías A. Avila

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