PB2003: REAL-WORLD TREATMENT PATTERNS OF PATIENTS (PTS) WITH HIGHER-RISK MYELODYSPLASTIC SYNDROME (MDS) IN A US REAL-WORLD EVIDENCE DATABASE (COTA) by Rami S. Komrokji, Leyla Hernandez- Donoso, Sejla Hodzic, Henry Owusu, Kevin Nolan, Claire Nourry, María Díez Campelo

Get full text

SHP1 and SHP2 inhibition enhances the pro-differentiative effect of phorbol esters: an alternative approach against acute myeloid leukemia by Alejandro Pérez-Fernández, Guillermo López-Ruano, Rodrigo Prieto-Bermejo, Carla Ijurko, María Díez-Campelo, Fermín Sánchez-Guijo, Ángel Hernández-Hernández

Get full text

Myelodysplasia-associated immunophenotypic alterations of bone marrow cells in myeloma: are they present at diagnosis or are they induced by lenalidomide? by Sergio Matarraz, Bruno Paiva, María Diez-Campelo, Lucia-López Corral, Estefanía Pérez, Maria-Victoria Mateos, Pilar Giraldo, Miguel T. Hernández, Jesús F. San Miguel, Alberto Orfao

Get full text

Targeting NOX2 and glycolytic metabolism as a therapeutic strategy in acute myeloid leukaemia by Carla Ijurko, Marta Romo-González, Rodrigo Prieto-Bermejo, María Díez-Campelo, María-Belén Vidriales, Sandra Muntión, Fermín Sánchez-Guijo, Jesús Sánchez-Yagüe, Ángel Hernández-Hernández

Get full text

P714: DISSECTING THE CLINICAL HETEROGENEITY OF ISOLATED TRISOMY 8 MYELODYSPLASTIC SYNDROMES THROUGH MUTATIONAL PROFILE by Sofía María Toribio Castelló, Sandra Castaño, Angela Villaverde-Ramiro, Esperanza Such, Montserrat Arnan, Francesc Solé, Marina Díaz Beyá, María Díez-Campelo, Mónica del Rey, Teresa González, Jesus Hernández Rivas

Get full text

Mesenchymal stem cells expanded in vitro with human serum for the treatment of acute and chronic graft-versus-host disease: results of a phase I/II clinical trial by Jose A. Pérez-Simon, Olga López-Villar, Enrique J. Andreu, José Rifón, Sandra Muntion, María Diez Campelo, Fermín M. Sánchez-Guijo, Carmen Martinez, David Valcarcel, Consuelo del Cañizo

Get full text

Molecular profiling of pre- and post- 5-azacytidine myelodysplastic syndrome samples identifies predictors of response by Mónica del Rey González, Mónica del Rey González, Sohini Chakraborty, Jesús María Hernández-Sánchez, María Diez Campelo, Christopher Y. Park, Jesús María Hernández Rivas, Jesús María Hernández Rivas

Get full text

Eltrombopag increases the hematopoietic supporting ability of mesenchymal stem/stromal cells by Sandra Muntión, Silvia Preciado, Elena Sánchez-Luis, Luis Corchete, María Díez-Campelo, Lika Osugui, Gerardo-Javier Martí-Chillón, María-Belén Vidriales, Almudena Navarro-Bailón, Javier De Las Rivas, Fermín Sánchez-Guijo

Get full text

The effect of mesenchymal stem cells on the viability, proliferation and differentiation of B-lymphocytes by Soraya Tabera, José A. Pérez-Simón, María Díez-Campelo, Luis I. Sánchez-Abarca, Belén Blanco, Antonio López, Ana Benito, Enrique Ocio, Fermín M. Sánchez-Guijo, Consuelo Cañizo, Jesús F. San Miguel

Get full text

S166: KER-050 TREATMENT IMPROVED MARKERS OF ERYTHROPOIETIC ACTIVITY AND HEMATOPOIESIS OVER SIX MONTHS WHICH RESULTED IN HEMATOLOGICAL RESPONSES ACROSS A BROAD, LOWER-RISK MDS POPUL... by Aristoteles Giagounidis, Thomas Cluzeau, María Díez Campelo, David Ross, Lynette Chee, Shuhying Tan, Christine Graham, Wei Feng, Ming Yang, Ying Jiang, Miranda Ross, Allie Mcginty, Suresh Bobba, Christopher Rovaldi, Simon Cooper, Jen Salstrom

Get full text

Microvesicles from Mesenchymal Stromal Cells Are Involved in HPC-Microenvironment Crosstalk in Myelodysplastic Patients. by Sandra Muntión, Teresa L Ramos, María Diez-Campelo, Beatriz Rosón, Luis Ignacio Sánchez-Abarca, Irena Misiewicz-Krzeminska, Silvia Preciado, María-Eugenia Sarasquete, Javier de Las Rivas, Marcos González, Fermín Sánchez-Guijo, María-Consuelo Del Cañizo

Get full text

Treatment with bortezomib of human CD4+ T cells preserves natural regulatory T cells and allows the emergence of a distinct suppressor T-cell population by Belén Blanco, José A. Pérez-Simón, Luis I. Sánchez-Abarca, Teresa Caballero-Velazquez, Silvia Gutierrez-Cossío, Pilar Hernández-Campo, María Díez-Campelo, Carmen Herrero-Sanchez, Concepción Rodriguez-Serrano, Carlos Santamaría, Fermín M. Sánchez-Guijo, Consuelo del Cañizo, Jesús F. San Miguel

Get full text

Impaired expression of DICER, DROSHA, SBDS and some microRNAs in mesenchymal stromal cells from myelodysplastic syndrome patients by Carlos Santamaría, Sandra Muntión, Beatriz Rosón, Belén Blanco, Olga López-Villar, Soraya Carrancio, Fermín M. Sánchez-Guijo, María Díez-Campelo, Stela Alvarez-Fernández, María E. Sarasquete, Javier de las Rivas, Marcos González, Jesús F. San Miguel, María Consuelo del Cañizo

Get full text

Chronic myelomonocytic leukemia with ring sideroblasts/SF3B1 mutation presents with low monocyte count and resembles myelodysplastic syndromes with-RS/SF3B1 mutation in terms of ph... by Blanca Xicoy, Helena Pomares, Mireia Morgades, Ulrich Germing, Montserrat Arnan, Mar Tormo, Laura Palomo, Elisa Orna, Matteo Della Porta, Felicitas Schulz, Marina Díaz-Beya, Ada Esteban, Antonieta Molero, Luca Lanino, Alejandro Avendaño, Francisca Hernández, Verónica Roldan, Marta Ubezio, Alberto Pineda, María Díez-Campelo, Lurdes Zamora

Get full text

Hematopoietic stem cells with granulo-monocytic differentiation state overcome venetoclax sensitivity in patients with myelodysplastic syndromes by Juan Jose Rodriguez-Sevilla, Irene Ganan-Gomez, Feiyang Ma, Kelly Chien, Monica Del Rey, Sanam Loghavi, Guillermo Montalban-Bravo, Vera Adema, Bethany Wildeman, Rashmi Kanagal-Shamanna, Alexandre Bazinet, Helen T. Chifotides, Natthakan Thongon, Xavier Calvo, Jesús María Hernández-Rivas, Maria Díez-Campelo, Guillermo Garcia-Manero, Simona Colla

Get full text

Panobinostat as part of induction and maintenance for elderly patients with newly diagnosed acute myeloid leukemia: phase Ib/II panobidara study by Enrique M. Ocio, Pilar Herrera, María-Teresa Olave, Nerea Castro, José A. Pérez-Simón, Salut Brunet, Albert Oriol, Marta Mateo, Miguel-Ángel Sanz, Javier López, Pau Montesinos, María-Carmen Chillón, María-Isabel Prieto-Conde, María Díez-Campelo, Marcos González, María-Belén Vidriales, María-Victoria Mateos, Jesús F. San Miguel

Get full text

Outcomes and effect of somatic mutations after erythropoiesis stimulating agents in patients with lower-risk myelodysplastic syndromes by Juan Carlos Caballero, Julio Dávila, María López-Pavía, Esperanza Such, Teresa Bernal, Fernando Ramos, Marisa Calabuig, Jesús María Hernández Sánchez, Helena Pomares, Mercedes Sánchez Barba, María Abáigar, Bernardo González, Brayan Merchán, Reyes Sancho-Tello, Marta Callejas, Carolina Muñoz-Novas, Carlos Cerveró, Guillermo Sanz, Jesús María Hernández Rivas, María Díez Campelo;

Get full text

S165: CONTINUOUS TRANFUSION INDEPENDENCE WITH IMETELSTAT IN HEAVILY TRANSFUSED NON-DEL(5Q) LOWER-RISK MYELODYSPLASTIC SYNDROMES RELAPSED/REFRACTORY TO ERYTHROPOIESIS STIMULATING AG... by Uwe Platzbecker, Valeria Santini, Pierre Fenaux, Mikkael Sekeres, Michael Robert Savona, Yazan Madanat, María Díez Campelo, David Valcárcel, Thomas Illmer, Anna Jonášová, Petra Belohlavkova, Laurie Sherman, Tymara Berry, Souria Dougherty, Sheetal Shah, Qi Xia, Lixian Peng, Libo Sun, Ying Wan, Fei Huang, Annat Ikin, Shyamala Navada, Rami S. Komrokji, Amer M. Zeidan

Get full text

Chromothripsis Is a Recurrent Genomic Abnormality in High-Risk Myelodysplastic Syndromes. by María Abáigar, Cristina Robledo, Rocío Benito, Fernando Ramos, María Díez-Campelo, Lourdes Hermosín, Javier Sánchez-Del-Real, Jose M Alonso, Rebeca Cuello, Marta Megido, Juan N Rodríguez, Guillermo Martín-Núñez, Carlos Aguilar, Manuel Vargas, Ana A Martín, Juan L García, Alexander Kohlmann, M Consuelo Del Cañizo, Jesús M Hernández-Rivas

Get full text

S164: DISEASE MODIFYING ACTIVITY OF IMETELSTAT IN PATIENTS WITH HEAVILY TRANSFUSED NON-DEL(5Q) LOWER-RISK MYELODYSPLASTIC SYNDROMES RELAPSED/REFRACTORY TO ERYTHROPOIESIS STIMULATIN... by Valeria Santini, Uwe Platzbecker, Pierre Fenaux, Mikkael Sekeres, Michael Robert Savona, Yazan Madanat, María Díez Campelo, David Valcárcel, Thomas Illmer, Anna Jonášová, Petra Belohlavkova, Laurie Sherman, Tymara Berry, Souria Dougherty, Sheetal Shah, Qi Xia, Lixian Peng, Libo Sun, Ying Wan, Fei Huang, Annat Ikin, Shyamala Navada, Faye Feller, Amer M. Zeidan, Rami S. Komrokji

Get full text