PB2003: REAL-WORLD TREATMENT PATTERNS OF PATIENTS (PTS) WITH HIGHER-RISK MYELODYSPLASTIC SYNDROME (MDS) IN A US REAL-WORLD EVIDENCE DATABASE (COTA) by Rami S. Komrokji, Leyla Hernandez- Donoso, Sejla Hodzic, Henry Owusu, Kevin Nolan, Claire Nourry, María Díez Campelo

Get full text

SHP1 and SHP2 inhibition enhances the pro-differentiative effect of phorbol esters: an alternative approach against acute myeloid leukemia by Alejandro Pérez-Fernández, Guillermo López-Ruano, Rodrigo Prieto-Bermejo, Carla Ijurko, María Díez-Campelo, Fermín Sánchez-Guijo, Ángel Hernández-Hernández

Get full text

P714: DISSECTING THE CLINICAL HETEROGENEITY OF ISOLATED TRISOMY 8 MYELODYSPLASTIC SYNDROMES THROUGH MUTATIONAL PROFILE by Sofía María Toribio Castelló, Sandra Castaño, Angela Villaverde-Ramiro, Esperanza Such, Montserrat Arnan, Francesc Solé, Marina Díaz Beyá, María Díez-Campelo, Mónica del Rey, Teresa González, Jesus Hernández Rivas

Get full text

Mutational Profile Enables the Identification of a High-Risk Subgroup in Myelodysplastic Syndromes with Isolated Trisomy 8 by Sofía Toribio-Castelló, Sandra Castaño, Ángela Villaverde-Ramiro, Esperanza Such, Montserrat Arnán, Francesc Solé, Marina Díaz-Beyá, María Díez-Campelo, Mónica del Rey, Teresa González, Jesús María Hernández-Rivas

Get full text

Analysis of Intratumoral Heterogeneity in Myelodysplastic Syndromes with Isolated del(5q) Using a Single Cell Approach by Pamela Acha, Laura Palomo, Francisco Fuster-Tormo, Blanca Xicoy, Mar Mallo, Ana Manzanares, Javier Grau, Silvia Marcé, Isabel Granada, Marta Rodríguez-Luaces, María Diez-Campelo, Lurdes Zamora, Francesc Solé

Get full text

Eltrombopag increases the hematopoietic supporting ability of mesenchymal stem/stromal cells by Sandra Muntión, Silvia Preciado, Elena Sánchez-Luis, Luis Corchete, María Díez-Campelo, Lika Osugui, Gerardo-Javier Martí-Chillón, María-Belén Vidriales, Almudena Navarro-Bailón, Javier De Las Rivas, Fermín Sánchez-Guijo

Get full text

S166: KER-050 TREATMENT IMPROVED MARKERS OF ERYTHROPOIETIC ACTIVITY AND HEMATOPOIESIS OVER SIX MONTHS WHICH RESULTED IN HEMATOLOGICAL RESPONSES ACROSS A BROAD, LOWER-RISK MDS POPUL... by Aristoteles Giagounidis, Thomas Cluzeau, María Díez Campelo, David Ross, Lynette Chee, Shuhying Tan, Christine Graham, Wei Feng, Ming Yang, Ying Jiang, Miranda Ross, Allie Mcginty, Suresh Bobba, Christopher Rovaldi, Simon Cooper, Jen Salstrom

Get full text

Microvesicles from Mesenchymal Stromal Cells Are Involved in HPC-Microenvironment Crosstalk in Myelodysplastic Patients. by Sandra Muntión, Teresa L Ramos, María Diez-Campelo, Beatriz Rosón, Luis Ignacio Sánchez-Abarca, Irena Misiewicz-Krzeminska, Silvia Preciado, María-Eugenia Sarasquete, Javier de Las Rivas, Marcos González, Fermín Sánchez-Guijo, María-Consuelo Del Cañizo

Get full text

Hematopoietic stem cells with granulo-monocytic differentiation state overcome venetoclax sensitivity in patients with myelodysplastic syndromes by Juan Jose Rodriguez-Sevilla, Irene Ganan-Gomez, Feiyang Ma, Kelly Chien, Monica Del Rey, Sanam Loghavi, Guillermo Montalban-Bravo, Vera Adema, Bethany Wildeman, Rashmi Kanagal-Shamanna, Alexandre Bazinet, Helen T. Chifotides, Natthakan Thongon, Xavier Calvo, Jesús María Hernández-Rivas, Maria Díez-Campelo, Guillermo Garcia-Manero, Simona Colla

Get full text

Outcomes and effect of somatic mutations after erythropoiesis stimulating agents in patients with lower-risk myelodysplastic syndromes by Juan Carlos Caballero, Julio Dávila, María López-Pavía, Esperanza Such, Teresa Bernal, Fernando Ramos, Marisa Calabuig, Jesús María Hernández Sánchez, Helena Pomares, Mercedes Sánchez Barba, María Abáigar, Bernardo González, Brayan Merchán, Reyes Sancho-Tello, Marta Callejas, Carolina Muñoz-Novas, Carlos Cerveró, Guillermo Sanz, Jesús María Hernández Rivas, María Díez Campelo;

Get full text

S165: CONTINUOUS TRANFUSION INDEPENDENCE WITH IMETELSTAT IN HEAVILY TRANSFUSED NON-DEL(5Q) LOWER-RISK MYELODYSPLASTIC SYNDROMES RELAPSED/REFRACTORY TO ERYTHROPOIESIS STIMULATING AG... by Uwe Platzbecker, Valeria Santini, Pierre Fenaux, Mikkael Sekeres, Michael Robert Savona, Yazan Madanat, María Díez Campelo, David Valcárcel, Thomas Illmer, Anna Jonášová, Petra Belohlavkova, Laurie Sherman, Tymara Berry, Souria Dougherty, Sheetal Shah, Qi Xia, Lixian Peng, Libo Sun, Ying Wan, Fei Huang, Annat Ikin, Shyamala Navada, Rami S. Komrokji, Amer M. Zeidan

Get full text

Chromothripsis Is a Recurrent Genomic Abnormality in High-Risk Myelodysplastic Syndromes. by María Abáigar, Cristina Robledo, Rocío Benito, Fernando Ramos, María Díez-Campelo, Lourdes Hermosín, Javier Sánchez-Del-Real, Jose M Alonso, Rebeca Cuello, Marta Megido, Juan N Rodríguez, Guillermo Martín-Núñez, Carlos Aguilar, Manuel Vargas, Ana A Martín, Juan L García, Alexander Kohlmann, M Consuelo Del Cañizo, Jesús M Hernández-Rivas

Get full text

S164: DISEASE MODIFYING ACTIVITY OF IMETELSTAT IN PATIENTS WITH HEAVILY TRANSFUSED NON-DEL(5Q) LOWER-RISK MYELODYSPLASTIC SYNDROMES RELAPSED/REFRACTORY TO ERYTHROPOIESIS STIMULATIN... by Valeria Santini, Uwe Platzbecker, Pierre Fenaux, Mikkael Sekeres, Michael Robert Savona, Yazan Madanat, María Díez Campelo, David Valcárcel, Thomas Illmer, Anna Jonášová, Petra Belohlavkova, Laurie Sherman, Tymara Berry, Souria Dougherty, Sheetal Shah, Qi Xia, Lixian Peng, Libo Sun, Ying Wan, Fei Huang, Annat Ikin, Shyamala Navada, Faye Feller, Amer M. Zeidan, Rami S. Komrokji

Get full text

P732: ANALYSIS OF PATIENT-REPORTED FATIGUE IN IMERGE PH3 TRIAL OF IMETELSTAT VS PLACEBO IN HEAVILY TRANSFUSED NON-DEL(5Q) LOWER-RISK MYELODYSPLASTIC SYNDROMES R/R TO ERYTHROPOIESIS... by Mikkael Sekeres, Valeria Santini, María Díez Campelo, Rami S. Komrokji, Pierre Fenaux, Michael Robert Savona, Yazan Madanat, David Valcárcel, Thomas Illmer, Anna Jonášová, Petra Belohlavkova, Antoine Regnault, Kristin Creel, Nishan Sengupta, Laurie Sherman, Tymara Berry, Souria Dougherty, Sheetal Shah, Libo Sun, Ying Wan, Fei Huang, Annat Ikin, Shyamala Navada, Faye Feller, Amer M. Zeidan, Uwe Platzbecker

Get full text

Relevance of infections on the outcomes of patients with myelodysplastic syndromes, chronic myelomonocytic leukemia, and acute myeloid leukemia treated with hypomethylating agents:... by Laura Vilorio-Marqués, Christelle Castañón Fernández, Elvira Mora, Lorena Gutiérrez, Beatriz Rey Bua, Maria José Jiménez Lorenzo, Marina Díaz Beya, Miriam Vara Pampliega, Antonieta Molero, Joaquín Sánchez-García, Marisa Calabuig, Maria Teresa Cedena, Tzu Chen-Liang, Johana Alejandra Díaz Santa, Irene Padilla, Francisca Hernández, Rosana Díez, Pedro Asensi, Blanca Xicoy, Guillermo Sanz, David Valcárcel, María Diez-Campelo, Teresa Bernal

Get full text

Uncovering perturbations in human hematopoiesis associated with healthy aging and myeloid malignancies at single-cell resolution by Marina Ainciburu, Teresa Ezponda, Nerea Berastegui, Ana Alfonso-Pierola, Amaia Vilas-Zornoza, Patxi San Martin-Uriz, Diego Alignani, Jose Lamo-Espinosa, Mikel San-Julian, Tamara Jiménez-Solas, Felix Lopez, Sandra Muntion, Fermin Sanchez-Guijo, Antonieta Molero, Julia Montoro, Guillermo Serrano, Aintzane Diaz-Mazkiaran, Miren Lasaga, David Gomez-Cabrero, Maria Diez-Campelo, David Valcarcel, Mikel Hernaez, Juan P Romero, Felipe Prosper

Get full text

S173: RETROSPECTIVE STUDY OF LENALIDOMIDE DISCONTINUATION IN PATIENTS WITH MYELODYSPLASTIC SYNDROME HARBORING DEL(5Q). A HARMONY ALLIANCE STUDY by Elena Crisà, María Díez Campelo, Ulrich Germing, Elvira Mora Castera, Francisca Hernandez Mohedo, Kündgen Andrea, Ebeling Freja, Mikko Myllymäki, Martin Jädersten, Eva Hellström Lindberg, Detlef Haase, Isabella Capodanno, Antonella Poloni, Carlo Finelli, Monica Crugnola, Claudio Fozza, Anna Calvisi, Chiara Frairia, Giuseppe Pietrantuono, Marco Cerrano, Rosanna Ciancia, Daniela Barraco, Wolf-Karsten Hofmann, Axel Ruefer, Cécile Bally, Pierre Fenaux, Guillermo Sanz Santillana, Valeria Santini

Get full text

Machine Learning Improves Risk Stratification in Myelodysplastic Neoplasms: An Analysis of the Spanish Group of Myelodysplastic Syndromes by Adrian Mosquera Orgueira, Manuel Mateo Perez Encinas, Nicolas A Diaz Varela, Elvira Mora, Marina Díaz-Beyá, María Julia Montoro, Helena Pomares, Fernando Ramos, Mar Tormo, Andres Jerez, Josep F Nomdedeu, Carlos De Miguel Sanchez, Arenillas Leonor, Paula Cárcel, Maria Teresa Cedena Romero, Blanca Xicoy, Eugenia Rivero, Rafael Andres del Orbe Barreto, Maria Diez-Campelo, Luis E. Benlloch, Davide Crucitti, David Valcárcel

Get full text

P703: THE AIPSS-MDS MACHINE LEARNING MODEL PREDICTS OVERALL SURVIVAL AND LEUKEMIC TRANSFORMATION IN CMML: AN ANALYSIS OF THE SPANISH REGISTRY OF MDS by Adrian Mosquera-Orgueira, Manuel Mateo Perez Encinas, Nicolas Diaz Varela, Yu-Hung Wang, Elvira Mora, Marina Diaz-Beya, Maria Julia Montoro, Helena Pomares Marin, Fernando Ramos Ortega, Mar Tormo, Andres Jerez, Josep Nomdedeu, Carlos de Migue Sanchez, Leonor Arenillas, Paula Carcel, Maria Teresa Cedena Romero, Blanca Xicoy Cirici, Eugenia Rivero Arango, Rafael Andrés Del Orbe Barreto, Luis Benlloch, Chien-Chin Lin, Hwei-Fang Tien, María Díez Campelo, Davide Crucitti, David Valcárcel

Get full text

The transcription factor DDIT3 is a potential driver of dyserythropoiesis in myelodysplastic syndromes by Nerea Berastegui, Marina Ainciburu, Juan P. Romero, Paula Garcia-Olloqui, Ana Alfonso-Pierola, Céline Philippe, Amaia Vilas-Zornoza, Patxi San Martin-Uriz, Raquel Ruiz-Hernández, Ander Abarrategi, Raquel Ordoñez, Diego Alignani, Sarai Sarvide, Laura Castro-Labrador, José M. Lamo-Espinosa, Mikel San-Julian, Tamara Jimenez, Félix López-Cadenas, Sandra Muntion, Fermin Sanchez-Guijo, Antonieta Molero, Maria Julia Montoro, Bárbara Tazón, Guillermo Serrano, Aintzane Diaz-Mazkiaran, Mikel Hernaez, Sofía Huerga, Findlay Bewicke-Copley, Ana Rio-Machin, Matthew T. Maurano, María Díez-Campelo, David Valcarcel, Kevin Rouault-Pierre, David Lara-Astiaso, Teresa Ezponda, Felipe Prosper

Get full text